5 abstracts found.



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Introduction: tumour:stroma interactions

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Targeting tumour angiogenesis by targeting Angiopoietin/Tie signalling: from vascular regression over vascular normalisation to stromal reprogramming therapies

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Hellmut G. Augustin1

1Vascular Oncology and Metastasis, German Cancer Research Center, Heidelberg (DKFZ-ZMBH Alliance); Vascular Biology and Tumour Angiogenesis, Medical Faculty Mannheim (CBTM), Heidelberg University; Germ, Germany, Germany


“Intravital imaging reveals how stroma dictates heterogeneous responses to targeted therapy”

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Erik Sahai1

1The Francis Crick Institute, London, UK


E-cadherin deficiency a novel determinant of ROS1 inhibitor sensitivity

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Ilirjana Bajrami1,Stephen Pettitt1,Rachel Brough1,Helen Pemberton1,Jessica Frankum1,James Campbell1,Alan Ashworth2,Christopher Lord1

1ICR, LONDON, UK,2UCSF, SAN FRANCISCO, USA


CTEN (C-terminal Tensin-like) regulates head and neck cancer invasion and survival

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Jason Fleming1,Veronika Jenei1,Karwan Moutasim1,Matthew Ward1,Emma King1,4,Sassan Hafizi2,Dae Kim3,Jeremy Blaydes1,Gareth Thomas1

1University of Southampton, Southampton, UK,2University of Portsmouth, Portsmouth, UK,3St. George’s University Hospitals, London, UK,4Poole Hospital NHS Foundation Trust, Poole, UK