Construction and characterisation of novel fusion toxin targeted to cancer (DT-SCF)


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Sirisha Potala, Rama Verma

Indian Institute of Technology Madras, Tamil Nadu, India

Abstract

Background
Fusion toxins, an emerging class of targeted therapies, exhibit remarkable tumour specificity thus promising a better alternative to current therapies in treatment of cancers. The aim of this study was to evaluate the cytotoxicity and specificity of a novel fusion toxin, diphtheria toxin-stem cell factor (DT-SCF).

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