269 abstracts found.



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A National Platform for Molecular Diagnostics: Results from Phase I of the Cancer Research UK Stratified Medicine Programme

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Colin R Lindsay1,Emily Shaw1,James D Brenton2,Rachel Butler3,Jim Davies4,David Gonzalez de Castro5,Mike Griffiths6,Andrew Hanby7,Steve Harris4,David J Harrison8,Stephen R D Johnston9,Malcolm Mason10,Dion Morton11,Andrew G Nicholson12,Karin Oien13,Doris Rassl14,Jane Rogan15,Ian Walker1,Peter W M Johnson1

1Cancer Research UK, London, UK,2Cancer Research UK Cambridge Institute, Cambridge, UK,3Institute of Medical Genetics, Cardiff, UK,4University of Oxford, Oxford, UK,5The Centre for Molecular Pathology, Surrey, UK,6West Midlands Regional Genetics Laboratory, Birmingham, UK,7Leeds Institute of Cancer and Pathology, Leeds, UK,8University of St. Andrews, St. Andrews, UK,9The Royal Marsden NHS Foundation Trust, London, UK,10Cardiff University, Cardiff, UK,11The Queen Elizabeth Hospital, Birmingham, UK,12Royal Brompton and Harefield Hospitals NHS Foundation Trust, London, UK,13NHS Greater Glasgow and Clyde, Glasgow, UK,14Papworth Hospital NHS Foundation Trust, Cambridge, UK,15Manchester Cancer Research Centre, Manchester, UK


Signatures of ionising radiation in second malignancies

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Sam Behjati1,Gunes Gundem1,David Wedge1,Patrick Tarpey1,Nicole Roberts1,Andrea Richardson2,Ultan McDermott1,Steven Bova3,Adrienne Flanagan4,Michael Stratton1,Peter Campbell1

1Wellcome Trust Sanger Institute, Hinxton, UK,2Harvard Medical School, Boston, UK,3University of Tampere and Fimlab Laboratories, Tampere, Finland,4University College London, London, UK


Real-Time Diagnosis of Ovarian Cancer with the Surgical Intelligent Knife (iKnife)

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David Phelps1,Julia Balog1,2,Mona El-Bahrawy1,Abigail Speller1,Zoltan Takats1,Robert Brown1,Sadaf Ghaem-Maghami1

1Imperial College, London, UK,2Waters Corporation, Budapest, Hungary


Public understanding of the purpose of cancer screening: a population-based survey

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Jo Waller1,Yasemin Hirst1,Jane Wardle1,Christian von Wagner1

1UCL, London, UK


Variations in GPs’ Decisions to Investigate Suspected Lung Cancer: A Factorial Experiment Using Multimedia Vignettes

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Jessica Sheringham1,Rachel Sequeira1,Jonathan Myles2,Willie Hamilton3,Joe McDonnell4,Judith Offman2,Stephen Duffy2,Rosalind Raine0

1UCL, London, UK,2QMUL, London, UK,3University of Exeter, Exeter, UK,4London Borough of Waltham Forest, London, UK


Children’s Cancer and Leukaemia Group (CCLG) McElwain Award winner – Adamantinomatous craniopharyngioma contains senescent cells with tumour-inducing potential

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Mario Jose Gonzalez-Meljem1,Gabriela Carreno1,John Apps1,Scott Haston1,Christina Stache1,Tomas Stanley Jacques2,5,Colin Goding3,Jesus Gil4,Cynthia Lilian Andoniadou1,Juan Pedro Martinez-Barbera1

1University College London, London, UK,2University of Oxford, Oxford, UK,3Imperial College London, London, UK,4King’s College London, London, UK,5Great Ormond Street Hospital, London, UK


Multiregion copy number analysis reveals Wilms’ tumour genetic heterogeneity

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George Cresswell1,Borbala Mifsud1,John Apps2,3,Richard Williams2,3,Oystein Olsen3,Kathy Pritchard-Jones2,3,William Mifsud2,3,Nicholas M. Luscombe1

1The Francis Crick Institute, London, UK,2UCL Institute of Child Health, London, UK,3Great Ormond Street Hospital, London, UK


Young patients with HER2+ breast cancer rarely have a germline mutation in a known cancer predisposition gene

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Diana Eccles1,Li Na2,Tom Maishman1,Ellen Copson1,Ian Campbell2

1University of Southampton, Southampton, UK,2Peter Macallum Cancer Centre, Melbourne, Australia


Longitudinal single cell clonal analysis reveals evolutionary stasis and predetermined malignant potential in non-dysplastic Barrett’s Oesophagus

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Pierre Martinez1,Margriet R. Timmer2,Chiu T. Lau2,Sybren L. Meijer2,Fiebo J.W. ten Kate2,Rosalie C. Mallant-Hent3,9,Anton H.J. Naber4,9,Arnoud H.A.M. van Oijen5,9,Lubbertus C. Baak6,9,Pieter Scholten7,9,Clarisse J.M. Böhmer8,9,Paul Fockens2,Jacques J.G.H.M. Bergman2,9,Carlo C. Maley10,11,Trevor A. Graham1,Kausilia K. Krishnadath2,9

1Barts Cancer Institute – Queen Mary University of London, London, UK,2Academic Medical Center – University of Amsterdam, Amsterdam, The Netherlands,3Department of Gastroenterology and Hepatology, Flevoziekenhuis, Almere, The Netherlands,4Department of Gastroenterology and Hepatology, Tergooiziekenhuizen, Hilversum, The Netherlands,5Department of Gastroenterology and Hepatology, Medisch Centrum Alkmaar, Alkmaar, The Netherlands,6Department of Gastroenterology and Hepatology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands,7Department of Gastroenterology and Hepatology, Sint Lucas Andreas Ziekenhuis, Amsterdam, The Netherlands,8Department of Gastroenterology and Hepatology, Spaarne Ziekenhuis, Hoofddorp, The Netherlands,9Gastroenterological Association, Amsterdam, The Netherlands,10Center for Evolution and Cancer, University of California at San Francisco, San Francisco, CA, USA,11Biodesign Institute, School of Life Sciences, Arizona State University, Tempe, AZ, USA


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