322 abstracts found.



Molecular Profiling of Circulating Tumour Cells (CTCs) in Non-small cell lung cancer within the TRACERx study of Intratumoural Heterogeneity and Evolution

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Sakshi Gulati1,Francesca Chemi2,Dominic G Rothwell2,Deborah Burt2,Barbara Mesquita2,Christopher Wirth2,Gareth Wilson3,Jackie Pierce2,Ged Brady2,Charles Swanton4,Caroline Dive5
1Postdoctoral Scientist,2Cancer Research UK Manchester Institute,3The Francis Crick Institute,London, UK,4The Francis Crick Institute,London, UK and and on behalf of TRACERx consortium and Cancer Research UK Manchester/UCL Lung Cancer Centre of Excellence,5Cancer Research UK Manchester Institute and on behalf of TRACERx consortium and Cancer Research UK Manchester/UCL Lung Cancer Centre of Excellence

Cell fate imbalance in the Oesophageal Epithelium: mutant cell competition

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Maria Alcolea1
1Wellcome Trust-MRC Cambridge Stem Cell Institute

Targeting flap endonuclease 1 (FEN1) for personalization of ovarian cancer therapy

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Reem Ali1,Dorjbal Dorjsuren2,David Maloney2,Ajit Jadhav2,Anton Simeonov2,David Wilson III3,Anna Grabowska1,Emad Rakha1,Srinivasan Madhusudan1
1Division of Cancer & Stem Cells, School of Medicine, University of Nottingham, UK,2NIH Chemical Genomics Center, National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, USA,3Laboratory of Molecular Gerontology, Biomedical Research Center, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224-6825, USA

Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing

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Jonas Demeulemeester1,Parveen Kumar2,Elen K. Møller3,Silje Nord3,David C. Wedge4,April Peterson5,Randi R. Mathiesen6,Renathe Fjelldal7,Masoud Zamani Esteki8,A. Jason Grundstad9,Elin Borgen7,Lars O. Baumbusch10,Anne-Lise Børresen-Dale3,Kevin P. White9,Bjørn Naume11,Vessela N. Kristensen3,Peter Van Loo1,Thierry Voet2
1The Francis Crick Institute, London, UK / Human Genome Laboratory, Department of Human Genetics, University of Leuven, Leuven, Belgium,2Laboratory of Reproductive Genomics, Department of Human Genetics, University of Leuven, Leuven, Belgium / Single-cell Genomics Centre, Wellcome Trust Sanger Institute, Hinxton, UK,3Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway / K.G. Jebsen Center for Breast Cancer Research, Institute for Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway,4Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK,5Institute for Genomics & Systems Biology and Department of Human Genetics, University of Chicago, Chicago, Illinois, USA / (Present address) Laboratory of Genetics, University of Wisconsin, Madison, Wisconsin, USA,6Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway / Division of Surgery and Cancer Medicine, Department of Oncology, Oslo University Hospital, Radiumhospitalet, Oslo, Norway / (Present address) Department of Oncology, Akershus University Hospital, Lørenskog, Norway,7Department of Pathology, Oslo University Hospital, Radiumhospitalet, Oslo, Norway,8Laboratory of Reproductive Genomics, Department of Human Genetics, University of Leuven, Leuven, Belgium,9Institute for Genomics & Systems Biology and Department of Human Genetics, University of Chicago, Chicago, Illinois, USA,10Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway / (Present address) Department of Pediatric Research, Women and Children's Division, Oslo University Hospital, Rikshospitalet, Oslo, Norway,11K.G. Jebsen Center for Breast Cancer Research, Institute for Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway / Division of Surgery and Cancer Medicine, Department of Oncology, Oslo University Hospital, Radiumhospitalet, Oslo, Norway

A Hypoxia Transcriptomic Signature Predicting Benefit from Hypoxia-modifying Treatment for High Risk Bladder Cancer Patients

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Lingjian Yang1,Amanda Williamson1,Joely Irlam1,Helen Denley2,Peter Hoskin3,Ananya Choudhury1,Catharine West1
1University of Manchester,2Manchester Royal Infirmary,3Mount Vernon Hospital

Variations in Ribonucleotide Reductase subunit expression induce gemcitabine resistance in a cell cycle dependent manner in Suit-2 pancreatic cancer cells

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Kulbir Mann1,Paula Ghaneh2,William Greenhalf2
1Royal Liverpool University Hospital,2University of Liverpool

Iterative Data Multiplexing Identifies Therapeutic Candidates for Oral Squamous Cell Carcinoma

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Emma Shanks1,Matthew Davidson1
1Beatson Institute for Cancer Research

Cancer microvesicles induce Tissue Factor-related procoagulant activity in endothelial cells in vitro.

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M. Adeola Adesanya1,Leigh Madden2,Anthony Maraveyas1
1Hull York Medical school,2School of Biological, Biomedical and Environmental Sciences

20-Hydroxyeicosatetraenoic acid and its cytochrome-P450 isoform expression are linked to tumor proliferation in bladder cancer cells (RT4)

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Yilun Zhang1,Victor Garcia2,Cheng-Chia Wu3,Michal Laniado Schwartzman4
1New York Medical College,2Dept of Pharmacology, Yale University, New Haven, CT,3Department of Medicine, Greenwich Hospital, Greenwich, CT,4Dept of Pharmacology, New York Medical College

In vivo Skin dose measurements using TLD for head and neck patients treated with IMRT and 3D-CRT

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Khaldoon Radaideh1
1Al Qassim University

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