915 abstracts found.



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Regulation of tumor stroma angiogenesis by fibroblast cell-derived tetrahydrobiopterin

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Liye Chen1, Jihui Wang2, Jiliang Li1, Russell Leek1, Helen Turley1, David Kerr1, Adrian Harris1, Shijie Cai1

1University of Oxford, UK, 2College of Biology & Food Engineering, Dalian Polytechnic University, China


Molecular basis for maize as a risk factor for oesophageal cancer in a South African population via a prostaglandin E2 positive feedback mechanism

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Ryan C. Pink1, Tracey A. Bailey1, Jehu E. Iputo2, Alastair M. Sammon3, Anthony C. Woodman1

1Cranfield Health, Cranfield University, Bedfordshire, UK, 2Dept of Physiology, Faculty of Health Sciences, Walter Sisulu University, Mthatha, South Africa, 3Dept of Surgery, Gloucestershire Royal Hospital, Gloucester, UK


Intravascular survival and proliferation determine brain metastasis formation

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W Shawn Carbonel, Olaf Ansorge, Ruth Muschel

University of Oxford, UK


The tumour suppressor protein LIMD1 specifically binds the HIF-prolyl hydroxylases and pVHL and represses HIF-1 mediated transcription

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Thomas M Webb1, Thilo Hagen1, Daniel E Foxler1, Maureen Mee1, Yunfeng Feng2, Gregory D Longmore2, Tyson V Sharp1

1University of Nottingham, UK, 2Washington University, St. Louis, USA


SAGE and MPSS profiling of stroma to identify regulators of prostate development and tumourigenesis

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Brigid Orr1, Griet Vanpoucke1, Oliver Grace1, Raymond Chan1, George Ashley1, Karin Williams2, Omar Franco2, Simon Hayward2, Richard Anderson1, Axel Thomson1

1Medical Research Council, Edinburgh, Lothian, UK, 2Vanderbilt University, Nashville, USA


Dietary flavonoids inhibit the anti-cancer effects of the proteasome inhibitor Bortezomib

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Feng-Ting Liu1, Samir G Agrawal1, Zanyar Movasaghi2, Peter B Wyatt3, Ihtesham U Rehman2, John G Gribben4, Adrian C Newland1, Li Jia1

1Institute of Cell and Molecular Science, Queen Mary University of London, London, UK, 2Department of Materials /IRC in Biomedical Materials, Queen Mary University of London, London, UK, 3School of Biological and Chemical Sciences, Queen Mary University of London, London, UK, 4Centre for Experimental Cancer Medicine, Institute of Cancer, Queen Mary University of London, London, UK


Wnt-11 promotes neuroendocrine-like differentiation, cell survival and migration in advanced prostate cancer

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Pinar Uysal-Onganer1, Soraya Diez1, Yoshiaki Kawano1, Siobhan Darrington1, Marjorie Walker1, Jonathan Waxman1, Robert Kypta2

1Imperial College London, London, UK, 2Centre for Cooperative Research in Biosciences, Bilbao, Spain


Inhibiting BCL-6

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Toni Hoffmann, Rob Ford, Paul Ko Ferrigno

Leeds Institute of Molecular Medicine, Leeds, West Yorkshire, UK


Identification of androgen receptor transcriptional complexes on distinct promoter targets

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Charlie Massie1, Falk Butter2, Andy Lynch1, Boris Adryan3, Nuno Barbosa-Morais1, Naomi Sharma1, Maxine Tran2, Matthias Mann1, David Neal1, Ian Mills1

1Cancer Research UK Cambridge Research Institute, University of Cambridge, UK, 2Max-Planck-Institute, Martinsried, Germany, 3Cambridge Systems Biology Centre, University of Cambridge, UK


CRT0066101, a small molecule inhibitor of protein kinase D, demonstrates in vitro and in vivo anticancer efficacy

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Stephen Jamieson, Azadeh Bagherzadeh, Mark Charles, Neil Jones, Florence Chan, Rachel Sutherland, Gregoire Pave, Julia Gilliatt, Kevin Stewart, Tim Hammonds, Caroline Foxton, Tony Raynham, Lloyd Kelland, Christopher Ireson

Cancer Research Technology Discovery Laboratories, University College London, London, UK


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