915 abstracts found.



Results filter

CRT0066101, a small molecule inhibitor of protein kinase D, demonstrates in vitro and in vivo anticancer efficacy

Year:

Session type:

Stephen Jamieson, Azadeh Bagherzadeh, Mark Charles, Neil Jones, Florence Chan, Rachel Sutherland, Gregoire Pave, Julia Gilliatt, Kevin Stewart, Tim Hammonds, Caroline Foxton, Tony Raynham, Lloyd Kelland, Christopher Ireson

Cancer Research Technology Discovery Laboratories, University College London, London, UK


Intravascular survival and proliferation determine brain metastasis formation

Year:

Session type:

W Shawn Carbonel, Olaf Ansorge, Ruth Muschel

University of Oxford, UK


Identification and characterisation of small molecule inhibitors of the atypical protein kinase C family (aPKC)

Year:

Session type:

Christelle Soudy1, Frederic Elustondo1, Christian Dillon1, Alex Boakes1, Carine Rosse2, Mark Linch2, Sven Kjaer2, Brenda Kostelecky2, Sarah Kaye1, Caroline Barton1, Aurore Lejeune1, Neil McDonald2, Peter Parker2, Caroline Foxton1, Tim Hammonds1, Lloyd Kelland1, Jon Roffey1

1Cancer Research Technology Discovery Laboratories, University College London, London, UK, 2London Research Institute, London, UK


The tumour suppressor protein LIMD1 specifically binds the HIF-prolyl hydroxylases and pVHL and represses HIF-1 mediated transcription

Year:

Session type:

Thomas M Webb1, Thilo Hagen1, Daniel E Foxler1, Maureen Mee1, Yunfeng Feng2, Gregory D Longmore2, Tyson V Sharp1

1University of Nottingham, UK, 2Washington University, St. Louis, USA


The αvβ6 integrin – a novel target for antibody conjugated magnetic fluid hyperthermia in squamous cell carcinoma

Year:

Session type:

Daniel Marsh1, Heide Kogelberg1, Kim Vigor1, Paul Southern2, Berend Tolner1, Jag Chana3, Quentin Pankhurst2, Kerry Chester1

1Cancer Institute, UCL, London, UK, 2London Centre of Nanotechnology, London, UK, 3Royal Free Hospital, London, UK


SAGE and MPSS profiling of stroma to identify regulators of prostate development and tumourigenesis

Year:

Session type:

Brigid Orr1, Griet Vanpoucke1, Oliver Grace1, Raymond Chan1, George Ashley1, Karin Williams2, Omar Franco2, Simon Hayward2, Richard Anderson1, Axel Thomson1

1Medical Research Council, Edinburgh, Lothian, UK, 2Vanderbilt University, Nashville, USA


An in vitro study of the pro‑apoptotic properties of green tea polyphenols in neoplastic cell lines

Year:

Session type:

Lakshman Nalluri1, David Jamieson3, Trevor Jackson3, Lisa Lee-Jones2

1Northumbria University, Newcastle-upon-Tyne, UK, 2Manchester Metropolitan University, Manchester, UK, 3Newcastle University, Newcastle-upon-Tyne, UK


Wnt-11 promotes neuroendocrine-like differentiation, cell survival and migration in advanced prostate cancer

Year:

Session type:

Pinar Uysal-Onganer1, Soraya Diez1, Yoshiaki Kawano1, Siobhan Darrington1, Marjorie Walker1, Jonathan Waxman1, Robert Kypta2

1Imperial College London, London, UK, 2Centre for Cooperative Research in Biosciences, Bilbao, Spain


Second-line treatment of ovarian carcinoma with pegylated liposomal doxorubicin (Caelyx®)

Year:

Session type:

Richard Turkington, Paula Scullin, Joanne Millar

Northern Ireland Cancer Centre, Belfast, Northern Ireland, UK


Identification of androgen receptor transcriptional complexes on distinct promoter targets

Year:

Session type:

Charlie Massie1, Falk Butter2, Andy Lynch1, Boris Adryan3, Nuno Barbosa-Morais1, Naomi Sharma1, Maxine Tran2, Matthias Mann1, David Neal1, Ian Mills1

1Cancer Research UK Cambridge Research Institute, University of Cambridge, UK, 2Max-Planck-Institute, Martinsried, Germany, 3Cambridge Systems Biology Centre, University of Cambridge, UK


Page 2 of 92« First...2...25...Last »