915 abstracts found.



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The potential utility of circulating tumour cells (CTCs) as biomarkers in small cell lung cancer (SCLC)

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Jian-Mei Hou1, Alastair Greystoke1, Matthew Krebs1, Amanda Willianmson1, Lee Lancashire1, Linda Ashcroft2, Paul Lorigan2, Sarah Hughes1, Caroline Dive1, Fiona Blackhall2

1Paterson Institute for Cancer Research, Manchester, UK, 2Christie Hospital, Manchester, UK


UK health professionals’ attitudes and knowledge regarding human papilloma virus (HPV) vaccination

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Tom G Hopkins, Nick J Wood, Robert M West, Jonathan C Darling

University of Leeds, Leeds, UK


Effect of diet on APC mutation spectra in sporadic colorectal tumours from the EPIC-Norfolk Study

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Laura Gay1, Mark Arends2, Panagiota Mitrou3, Richard Ball4, Sheila Bingham1

1University of Cambridge Pathology Department, Cambridge, UK, 2World Cancer Research Fund International, London, UK, 3Norfolk and Norwich University Hospital Pathology Department, Norwich, UK


A phase I/II trial of radioimmunotherapy with 131Iodine labelled A5B7 anti-CEA antibody (131I-A5B7) in combination with Combretastatin-A4-Phosphate (CA4P) in advanced gastrointestinal carcinomas

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Andrew Gaya1, Gairin Dancey4, Mike Stratford3, Shokri Othman4, Marivic Ricamara4, Surinder Sharma4, jane Boxall1, Linda Poupard1, John Violet4, Alan Green4, Lisa Folkes4, Anwar Padhani2, Gordon Rustin1, Richard Begent4, Tim Meyer4

1Mount Vernon Hospital, Northwood, Middlesex, UK, 2Paul Strickland Scanner Centre, Northwood, Middlesex, UK, 3Gray Cancer Institute, Northwood, Middlesex, UK, 4Royal Free Hospital, London, UK


Immunological targeting of the cancer phosphoproteome

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Mark Cobbold2, Andrew Norris4, Fiyas Mohammed1, Joy M. Polefrome4, Jie Qian4, Andrea M. De Santis4, Angela L. Zarling3, Jefferey Shabanowitz4, Benjamin E. Willcox1, Michael E. Williams5, Donald F. Hunt4, Victor H. Engelhard3

1CR-UK Institute for Cancer Studies, University of Birmingham, Birmingham, UK, 2Department of Clinical Immunology, University of Birmingham, Birmingham, UK, 3Beirne Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA, 4Department of Chemistry, University of Virginia, Charlottesville, VA, USA, 5Division of Hematology/Oncology, University of Virginia School of Medicine, Charlottesville, VA, USA


Access to optimal cytotoxic therapy in patients with metastatic colorectal cancer (mCRC): results in unselected patients within the South East London Cancer Network (SELCN)

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Gurdip Azad1, Nicholas Maisey1, Rahela Osbourne2, Gareth Parker1

1Guy's and St Thomas' Hospital, London, UK, 2Queen Elizabeth Hospital, Woolwich, UK


Targeting the plekstrin homology domain

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Tom Elliott1, Joseph Nemeth1, Alexander Gray2, Pete Downes2, Stuart Conway1

1University of St Andrews, Fife, UK, 2University of Dundee, Dundee, UK


The role of wnt signalling in development of ulcerative colitis-associated colorectal carcinogenesis

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Germaine Caldwell, Carolyn Jones, Glenn Matthews, Dion Morton

University of Birmingham, UK


Novel cambinol analogues as sirtuin inhibitors: design, synthesis and biological evaluation

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Federico Medda1, Anna R. McCarthy1, Rupert Russell1, Joana Campbell2, Maureen Higgins2, Sonia Lain2, Nicholas J. Westwood1

1Centre for Biomolecular Sciences,University of St Andrews, St Andrews, Fife, UK, 2Departement of Surgery and Molecular Oncology, Medical School, University of Dundee, Dundee, UK


Generation of a fully human anti-CD20 antibody with improved effector function, through the combined use of Xenomouse and ribosome display technologies

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Ross Stewart1, George Thom1, John Lund1, Michaela Levens1, Gulin Guler-Gane1, Sarahya Raja2, Shenghua Wen2, Christophe Queva2, Naomi Laing2, Anne Van Abbema2, Ping Wang4, Carlos Chavez4, Larry L Green4, Xiaoadong Yang4, Mohammad Tabrizi3, Gadi Gazit-Bornstein2, David Blakey1, Carl Webster1

1MedImmune, Cambridge, UK, 2Astrazeneca, Waltham, MA, USA, 3MedImmune, Hayward, CA, USA, 4Amgen, Fremont, CA, USA


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