915 abstracts found.



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UK health professionals’ attitudes and knowledge regarding human papilloma virus (HPV) vaccination

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Tom G Hopkins, Nick J Wood, Robert M West, Jonathan C Darling

University of Leeds, Leeds, UK


Effect of diet on APC mutation spectra in sporadic colorectal tumours from the EPIC-Norfolk Study

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Laura Gay1, Mark Arends2, Panagiota Mitrou3, Richard Ball4, Sheila Bingham1

1University of Cambridge Pathology Department, Cambridge, UK, 2World Cancer Research Fund International, London, UK, 3Norfolk and Norwich University Hospital Pathology Department, Norwich, UK


A phase I/II trial of radioimmunotherapy with 131Iodine labelled A5B7 anti-CEA antibody (131I-A5B7) in combination with Combretastatin-A4-Phosphate (CA4P) in advanced gastrointestinal carcinomas

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Andrew Gaya1, Gairin Dancey4, Mike Stratford3, Shokri Othman4, Marivic Ricamara4, Surinder Sharma4, jane Boxall1, Linda Poupard1, John Violet4, Alan Green4, Lisa Folkes4, Anwar Padhani2, Gordon Rustin1, Richard Begent4, Tim Meyer4

1Mount Vernon Hospital, Northwood, Middlesex, UK, 2Paul Strickland Scanner Centre, Northwood, Middlesex, UK, 3Gray Cancer Institute, Northwood, Middlesex, UK, 4Royal Free Hospital, London, UK


Febrile neutropaenia in patients receiving TAC chemotherapy for breast cancer

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Jessica Scaife, Rebecca Matthews, Peter Jenkins

Gloucestershire Oncology Centre, Cheltenham General Hospital, Cheltenham, Gloucestershire, UK


Targeting the plekstrin homology domain

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Tom Elliott1, Joseph Nemeth1, Alexander Gray2, Pete Downes2, Stuart Conway1

1University of St Andrews, Fife, UK, 2University of Dundee, Dundee, UK


The role of wnt signalling in development of ulcerative colitis-associated colorectal carcinogenesis

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Germaine Caldwell, Carolyn Jones, Glenn Matthews, Dion Morton

University of Birmingham, UK


Novel cambinol analogues as sirtuin inhibitors: design, synthesis and biological evaluation

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Federico Medda1, Anna R. McCarthy1, Rupert Russell1, Joana Campbell2, Maureen Higgins2, Sonia Lain2, Nicholas J. Westwood1

1Centre for Biomolecular Sciences,University of St Andrews, St Andrews, Fife, UK, 2Departement of Surgery and Molecular Oncology, Medical School, University of Dundee, Dundee, UK


Generation of a fully human anti-CD20 antibody with improved effector function, through the combined use of Xenomouse and ribosome display technologies

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Ross Stewart1, George Thom1, John Lund1, Michaela Levens1, Gulin Guler-Gane1, Sarahya Raja2, Shenghua Wen2, Christophe Queva2, Naomi Laing2, Anne Van Abbema2, Ping Wang4, Carlos Chavez4, Larry L Green4, Xiaoadong Yang4, Mohammad Tabrizi3, Gadi Gazit-Bornstein2, David Blakey1, Carl Webster1

1MedImmune, Cambridge, UK, 2Astrazeneca, Waltham, MA, USA, 3MedImmune, Hayward, CA, USA, 4Amgen, Fremont, CA, USA


A rapid and sensitive assay to detect RET M918T mutations in tumor samples from patients with sporadic medullary thyroid cancer

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James Sherwood, Gillian Ellison, John C Smith, Alan Wookey, Anderson Ryan

AstraZeneca, Alderley Park, UK


The removal of multiplicative, systematic bias allows integration of breast cancer gene expression datasets – improving meta-analysis and prediction of prognosis

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Andrew Sims1, Graeme Smethurst2, Yvonne Hey2, Michal Okoniewski2, Stuart Pepper2, Anthony Howell3, Crispin Miller2, Robert Clarke2

1University of Edinburgh, UK, 2University of Manchester, UK, 3Christie Hospital, Manchester, UK


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