868 abstracts found.



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Construction and characterisation of novel fusion toxin targeted to cancer (DT-SCF)

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Sirisha Potala, Rama Verma

Indian Institute of Technology Madras, Tamil Nadu, India


Efficacy and toxicities of a reduced dose sunitinib regimen in metastatic renal cell carcinoma

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Wei Seong Ooi1, Ko Ko Lin Thaw1, Valerie Khoo1, Vanessa Khoo1, Ravindran Kanesvaran1, Alexandre Chan3, Miah Hiang Tay1, Chee Keong Toh1, Min-Han Tan1

1National Cancer Centre Singapore, Singapore, 2National Cancer Centre Singapore, Singapore


Biological properties of the novel Chk1 inhibitor SAR-020106

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Paul Eve1, Mike Walton1, Angela Hayes1, Melanie Valenti1, Alexis De Haven Brandon1, Kathy Boxall1, Wynne Aherne1, Sue Eccles1, Gary Box1, Florence Raynaud1, David Williams2, Ian Collins1, John Reader2, Michelle Garrett1

1The Institute of Cancer Research, Surrey, UK, 2Sareum Ltd, Cambridge, UK


Combined targeting of Aurora B (AZD1152) and MEK1/2 (AZD6244) kinases leads to enhancement of anti-tumour effects in vivo

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Rajesh Odedra1, Simon P Heaton2, Armelle Logie1, Elizabeth Anderson1, Paul D Smith1, Robert W Wilkinson1

1AstraZeneca Pharmaceuticals, Macclesfield, UK, 2The Institute of Cancer Research, Sutton, UK


Phase I evaluation of radioimmunotherapy with 131I-CHT25 in patients with refractory IL2-receptor-expressing lymphomas

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Richard Begent2, Christopher McNamara2, Philip Ross1, James Ritchie1

1Cancer Research UK, London, UK, 2Royal Free Hospital, London, UK


Aspirin, non-steroidal anti-inflammatory drug and paracetamol use is associated with an increased risk of prostate cancer in a large, population-based, case-control study

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Ali Murad1, Liz Down1, George Davey Smith1, Jenny Donovan1, Janet Athene Lane1, Freddie Hamdy2, David Neal3, Richard Martin1

1University of Bristol, UK, 2John Radcliffe Hospital, Oxford, UK, 3University of Cambridge, UK


Radiotherapy-related heart damage in breast cancer patients is predicted by cutaneous telangiectasiae

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Chris Talbot1, George Tanteles1, Irene Peat1, Ahmed Osman1, Gerry McCann2, Steve Chan3, Julian Barwell1, R. Paul Symonds1

1University of Leicester, UK, 2University Hospitals of Leicester, Glenfield Hospital, UK, 3Nottingham University Hospitals NHS Trust, UK


Lifestyle intervention improves functional capacity in men on androgen deprivation therapy for prostate cancer

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Liam Bourke1, Helen Crank1, Amanda Daley3, Derek Rosario2, John Saxton1

1Sheffield Hallam University, UK, 2University of Sheffield, UK, 3University of Birmingham, UK


A study of the relationship between drug efficacy/toxicity and platinum-DNA adduct formation in pre- and post-infusion lymphocyte samples from patients receiving platinum-based chemotherapy

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A L Thomas1, A Zayed2, J P Wood1, H Reid2, GDD Jones1, B L Sharp2

1University of Leicester, UK, 2Loughborough University, UK


Plasma phytanic acid concentration and risk of prostate cancer

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Alison Price, Naomi Allen, Timothy Key

University of Oxford, UK


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