826 abstracts found.



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Tetrahydrobiopterin synthesis in cancer-associated fibroblasts promotes tumour angiogenesis and progression

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Xin Zeng (1), Liye Chen (1), Michael Presz (1), Simon Briggs (1), Russell leek (1), Gillies McKenna (1), Adrian Harris (1), Shijie Cai (1)
University of Oxford, Oxford, United Kingdom (1)

Combination therapy with an Aurora B kinase inhibitor AZD1152 and AraC, shows enhanced tumouricidal activity in a preclinical model of acute myeloid leukaemia (AML)

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Rajesh Odedra (1), Robert W. Wilkinson (1), Sarah V. Holt (2), John R. Foster (1), Elizabeth Anderson (1)
AstraZeneca, Alderley Park, United Kingdom (1), Paterson Institute of Cancer Research, Manchester, United Kingdom (2)

Structural characterisation of human mitotic kinesin – KIF15

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Marta Kozlowska (1), Venkatasubramanian Ulaganathan (1), Frank Kozielski (1)
The Beatson Institute for Cancer Research, Glasgow, United Kingdom (1)

MGMT methylation is strongly associated with and may precede IDH1/IDH2 mutations in adult astrocytic and oligodendroglial tumours

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Shani Mulholland (1), Deborah S Malley (1), Rifat Hamoudi (1), Sylvia Kocialkowski (1), Danita Pearson (1), V.Peter Collins (1), Koichi Ichimura (1)
Division of Molecular Histopathology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom (1)

Gene expression profile induced by genotoxic and non-genotoxic carcinogens in the rat kidney cells

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Kate Bloch (1), Edward A Lock (1), Andrew Evans (1)
Liverpool John Moores University, Liverpool, United Kingdom (1)

The relationships between the systemic inflammatory response, plasma and red cell B vitamins concentrations and survival in patients with colorectal cancer

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Elaine Leung (1), Campbell Roxburgh (1), Dinesh Talwar (2), Dennis O'Reilly (2), Ruth McKee (1), Paul Horgan (1), Donald McMillan (1)
University Department of Surgery, Glasgow, United Kingdom (1), University Department of Biochemistry, Glasgow, United Kingdom (2)

Piwil2 expression selects for known stem-cell and cancer stem-cell markers in LNCaP prostate cancer cell line

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Deepali Pal (1), Craig Robson (1), Stuart Williamson (1), Karim Nayernia (2), Hamid Reza Soleimanpour-Lichaei (2), Rakesh Heer (1)
Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom (1), North East England Stem Cell Institute, Newcastle University, Newcastle upon Tyne, United Kingdom (2)

miR-224 is marker of poor prognosis in breast cancer.

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Sharon McGee (1), Laoighse Mulrane (1), Donal Brennan (1), Susan McDonnell (1), Karin Jirstrom (2), Darran O'Connor (1), William Gallagher (1)
University College Dublin, Dublin, Ireland (1), Lund University, Lund, Sweden (2)

3D tumour models for the assessment of tumour micro-environment targeted therapies

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David Onion (1), Richard Argent (1), Rajendra Kumari (1), Amy Axel (2), Brett Hall (2), Sue Watson (1)
Ex Vivo Cancer Pharmacology Centre of Excellence, Division Of Pre-Clinical Oncology, University of Nottingham, Nottingham, United Kingdom (1), OthoBiotech, Oncology Research & Development, Beerse, Belgium (2)

Cadmium inhibits gelatinolytic activities of MMP2 and MMP9: another possible mechanism of cadmium-induced carcinogenesis

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Livia Lacorte (1), Carolina Sarobo (1), Elaine Porto (1), Luis Justulin Jr (1), Flavia Delella (1), Sergio Felisbino (1)
Sao Paulo State University UNESP, Botucatu, SP, Brazil (1)

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