777 abstracts found.



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Parallel functional genetic and compound screens identify WEE1 inhibition as a therapeutic strategy for cancers with defects in Fanconi Anaemia and HR pathways

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Marieke Aarts1, Ilirjana Bajrami1, Richard Elliott1, Christopher Lord1, Alan Ashworth1, Nicholas Turner1,2
1Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London, UK, 2Royal Marsden Hospital, London, UK

Cdc42 is required for melanoblast population of the developing mouse embryo

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Emma Woodham1, Ang Li1, Ben Tyrrell1, Heather Spence1, Cord Brakebusch2, Laura Machesky1
1Beatson Institute for Cancer Research, Glasgow, UK, 2Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark

Targeting DNA damage repair pathways to modulate pancreatic ductal adenocarcinoma response to DNA damaging agents

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Elaina Maginn1, Camila Sousa1, Hani Gabra1, Harpreet Wasan1, Euan Stronach1
1Imperial College London, London, UK

Delineating the apoptotic response underlying DNA-PKcs inhibitor-mediated restoration of cisplatin sensitivity

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Elaina Maginn1, Edward Curry1, Yan Dai1, Hani Gabra1, Harpreet Wasan1, Euan Stronach1
1Imperial College London, London, UK

“We are leading the group and the process”– The views and experiences of a patient and carer group involved in a research grant allocation

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Ian Lewis1, Anita Howman1, Sioned Pearce1
1Tenovus, Cardiff, UK

Differences in test characteristics between the first two rounds of the English Bowel Cancer Screening Programme

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Ben Kearns1, Sophie Whyte1, James Chilcott1
1University of Sheffield, Sheffield, UK

Impact of co-expression of HER family members on prognosis and survival of patients with metastatic colon cancer

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Said Abdullah Khelwatty1, Sharadah Essapen1,2, Izhar Bagwan3, Margaret Green3, Alan Seddon1, Helmout Modjtahedi1
1School of Life Sciences, Kingston University London, Kingston, UK, 2St. Lukes Cancer Centre, Royal Surrey County Hospital, Guildford, UK, 3Department of Histopathology, Royal Surrey County Hospital, Guildford, UK

Bringing Quality to Life: A Shared Vision – The Quality Improvement Group in Oncology and Haematology Clinical Trials (OHCT) at Guys and St Thomas’ Foundation Trust

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Natasha Baldwin1, Claire Brady-Martin1, Fidelma Cahill1, Nicholas Gomm1, Kylie Gyertson1, Jatinder Bisla1, Dawn Nunney1, Vasanthi Prathapan1, Oliver Pressey1, Antonio Querol-Rubiera1, Thomas Spencer1, Sharon Whelan1, Amy Winser1, Piranavan Sucindran1
1Guys and St Thomas' Foundation Trust, London, UK

HER-2 positive breast cancer detected through the NHS Breast Screening Programme – A description of the clinical features and the variation in management across the UK

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Emma Dugdale1, Mark Teo1, Shan Cheung2, olive Kearins2, Tim Perren1, David Dodwell1
1St James's Institute of Oncology, Leeds, UK, 2West Midlands Cancer Intelligence Unit, Birmingham, UK

How can we make screening logs better?

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Robin Carpenter1, Wendy Wood1
1University of Southampton Clinical Trials Unit, Southampton, UK

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