796 abstracts found.



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Low dose methotrexate and antibodies against cell surface markers cause lymphoblastic cell death by phagocytosis – phagoptosis

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Lucy Metayer1,G Amos A Burke2,Guy C Brown1

1University of Cambridge, Department of Biochemistry, Cambridge, UK,2University of Cambridge, Department of Paediatrics, Cambridge, UK


BACR Translational Award winner: Implementing personalised medicine in melanoma patients

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Immunotherapy of breast carcinomas using an anti Folate Receptor ? antibody: human monocytic cell-mediated killing triggered by IgG1 and IgE antibodies

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Matthew Fittall2,1,Anthony Cheung2,1,Gyula Petranyi1,Diana Rodriguez-Dominguez1,Heather Bax1,Panagiotis Karagiannis1,Kristina Ilieva2,1,Andrew Tutt2,Sophia Karagiannis1,2

1Skin Science, Division of Genetics and Molecular Medicine, Faculty of Life Sciences and Medicine, King’s College, London, UK,2Breakthrough Breast Cancer Unit, Division of Cancer Studies, Faculty of Life Sciences and Medicine, King’s College, London, UK


Deaths, DALY and Other related measures are high among Yemeni Breast cancer Women.

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Abeer Bawazir1,Amen Bawazir2

1Faculty of Dentistry, Aden University, Aden, Yemen,2College of Public Health and Health Informatics. KSAU-HS, Riyadh, Saudi Arabia


Co-occurring genetic alterations define major subsets of KRAS-mutant lung adenocarcinoma with unique biology, immune profiles and therapeutic vulnerabilities

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Ferdinandos Skoulidis1,Lauren Byers1,Lixia Diao1,Vassiliki Papadimitrakopoulou1,Julie Izzo1,Pan Tong1,Humam Kadara1,Jaime Rodriguez1,Edwin Parra1,Gordon Mills1,Padmanee Sharma1,Carmen Behrens1,John Minna2,Tim Heffernan1,Carlo Toniatti1,James Allison1,John Weinstein1,Jing Wang1,Ignacio Wistuba1,John Heymach1

1UT MD Anderson Cancer Center, Houston, USA,2UT Southwestern Medical Center, Dallas, USA,3Dana Farber Cancer Institute, Boston, USA,4Yale Cancer Center, New Haven, USA


OX40L gene polymorphism and breast cancer in a population in northern Iran

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Farhad Mashayekhi1,Rudabeh Vakilmonfared1,Hamid Saeidi saedi2

1University of Guilan, Rasht, Iran,2Guilan University of Medical Sciences, Rasht, Iran


The impact of E-selectin gene polymorphism on breast cancer

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Farhad Mashayekhi1,Golnaz Golnarnik1,Hamid Saeidi saedi2

1University of Guilan, Rasht, Iran,2Guilan University of Medical Sciences, Rasht, Iran


Genetic Testing for Hereditary and Early-Onset Colorectal Cancer Susceptibility in Sudanese Patients

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Omnia Elfateh Yousif1

1National Cancer Registry, Khartoum, Sudan


PSA response (PSAr) at 4 weeks associates with PSAr at 12 weeks and overall survival (OS) in chemotherapy naive metastatic castration resistant prostate cancer (mCRPC) patients treated with abiraterone acetate (AA)

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M Kolinsky1,P Rescigno1,D LorenteEstelles1,F Ferraldeschi1,D Bianchini1,S Sideris1,Z Zaferiou1,A Smith1,N Mehra1,E Grist1,A Jayaram1,R Perez Lopez1,J Mateo1,C Parker1,D Dearnaley1,E Hall1,N Tunariu1,G Attard1,J de Bono1

1Royal Marsden Hospital, Sutton, UK


Mutations in the transcriptional repressor REST predispose to Wilms tumour

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Shazia Mahamdallie1,Sandra Hanks1,Kristen Karlin2,3,Anna Zachariou1,Elizabeth Perdeaux1,Elise Ruark1,Chad Shaw3,Alexander Renwick3,Emma Ramsay1,Shawn Yost1,Anna Elliot1,The Wilms Tumor Susceptibility Collaboration (WTSC)1,Michael Capra4,Thomas McLean5,Anthony Renwick1,Sheila Seal1,Charles Stiller6,Neil Sebire7,Thomas Westbrook2,3,Nazneen Rahman1,8

1Division of Genetics & Epidemiology, Institute of Cancer Research, London, UK,2Verna & Marrs McLean Dept. of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, USA,3Dept of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA,4Our Lady’s Children’s Hospital, Dublin, UK,5Wake Forest University School of Medicine, Winston-Salem, USA,6Public Health England, Oxford, UK,7Dept of Histopathology and Paediatric Laboratory Medicine, Great Ormond Street Hospital, London, UK,8Cancer Genetics Unit, Royal Marsden Hospital NHS Foundation Trust, London, UK


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