796 abstracts found.



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Exosome switching: an mTORC1-dependent cellular stress response

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Sumeth Perera1,Shih-Jung Fan1,Ben Kroeger1,Kristie McCormick1,Siamak Redhai1,Aaron Leiblich1,Mark Wainwright1,Laura Corrigan1,Cameron Snell2,Helen Turley2,Helen Sheldon2,Katharine Carr1,Adrian Harris2,Clive Wilson1,Deborah Goberdhan1

1Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK,2The Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK


ESCAPE-ING trial: Effect of Sulforaphane on Prostate CAncer PrEvention-imagING evaluation

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Antonietta Melchini1,Vincent Gnanapragasam2,Tristan Barrett3,Omar Al Kadhi1,Maria Traka1,Richard Mithen1

1Food and Health Programme, Institute of Food Research,Norwich Research Park, Colney, Norwich, UK,2Academic Urology Group, Department of Surgery and Oncology, University of Cambridge, Cambridge, UK,3Department of Radiology, University of Cambridge School of Clinical Medicine, Box 111 Cambridge Biomedical Campus, Cambridge, UK


Prostate cancer tumours with germline BRCA2 mutations contain a higher burden of copy number alterations and c-MYC amplification

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Elena Castro2,1,Sarah Jugurnauth-Little1,Questa Karlsson1,Fatima Al-Shahrour2,Elena Piñeiro2,Daniel Leongamornlert1,Tokhir Dadaev1,Koveela Govindasami1,Michelle Guy1,Ros Eeles1,Zsofia Kote-Jarai1

1Institute of Cancer Research, Sutton, Surrey, UK,2Spanish National Cancer Research Centre, Madrid, Spain


Non-invasive exome analysis of circulating DNA

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Christopher G. Smith1,Andreas Mock1,James Hadfield1,Charles E. Massie1,Nitzan Rosenfeld1

1CRUK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, UK


Targeting mitotic vulnerability in ovarian cancer cells

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Charlotte Taylor1,Ahmed Ahmed1

1University of Oxford, Oxford, UK


Potent organo-osmium complex shifts metabolism in epithelial ovarian cancer cells

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Isolda Romero-Canelon1,Jessica M Hearn1,Alison F Munro2,Ying Fu1,3,Ana M Pizarro1,4,Matthew J Garnett5,Ultan McDermott5,Neil O Carragher2,Peter J Sadler1

1University of Warwick, Coventry, UK,2Edinburgh Cancer Research Centre, Edinburgh, UK,3Georgetown University Medical Centre, Washington, USA,4IMDEA Nanociencia, Madrid, Spain,5Wellcome Trust Sanger Institute, Cambridge, UK


Investigating the biology of high-risk medulloblastoma by targeted siRNA and whole genome CRISPR screening.

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Matthew Selby1,Peter Banks1,Ruth Cranston1,Martina Finetti1,Matthew Bashton1,Daniel Williamson1,Steven Clifford1

1Newcastle University, Newcastle Upon Tyne, UK


Residual toxicity following adjuvant chemotherapy in patients with colorectal cancer and need for specialised rehabilitation services

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Eniola Akinremi1,Victoria kunene2

1Prince Phillip hospital, Llanelli , Carmarthenshire , SA14 8QF, UK,2Queen Elizabeth hospital Birmingham, Birmingham, B15 2 Th, UK


RECQL4 helicase is a key prognostic, predictive and therapeutic target in breast cancer.

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Arvind Arora1,Devika Agarwal2,Huiming Lu3,Deborah L Croteau3,Roslin Russell4,Mohammed A Aleskandarany5,Tarek MA Abdel-Fatah1,Lisa L Wang6,Vilhelm A Bohr3,Srinivasan Madhusudan1

1Academic Unit of Oncology, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham, UK,2School of Science and Technology, Nottingham Trent University, Clifton campus, Nottingham, UK,3Laboratory of Molecular Gerontology, Biomedical Research Center, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA,4Cancer Research UK, Cambridge Research Institute, Cambridge, UK,5Department of Pathology, School of Medicine, University of Nottingham, Nottingham, UK,6Texas Children’s Cancer Center, Baylor College of Medicine, Houston,Texas, USA


Adjuvant radiation therapy of soft-tissue sarcoma achieves good results in elderly patients: The RMH experience, aged 80-94 years,1991-2014.

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Shane Zaidi1,Nidhin Raj1,Alison Dunlop1,Rolyn Alvarado1,Cerys Propert-Lewis1,Ian Judson1,Robin L Jones1,Charlotte Benson1,Sam Hackett1,Komel Khabra1,Omar Al-Muderis1,Christina Messiou1,Myles Smith1,Eleanor Moskovic1,Khin Thway1,Cyril Fisher1,Dirk Strauss1,Andrew Hayes1,Meirion Thomas1,Aisha Miah1

1The Royal Marsden NHS Foundation Trust, London, UK


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