578 abstracts found.



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Interaction between MUC1 and Galectin-3 promotes EGFR dimerization, activation and signalling in epithelial cancer cells

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Piyush Tushar1,Lu-Gang Yu2
1University of Liverpool,2Gastroenterology Unit, University of Liverpool

Overexpression of ABCB1 (MDR1) confers a common resistance mechanism to paclitaxel and selected PARP inhibitors in matched drug-sensitive and drug-resistant ovarian cancer cell lines

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Aparajitha Vaidyanathan1,Lynne Sawers1,Anne-Louise Gannon1,Probir Chakravarty2,Alison Scott1,Susan Bray1,Michelle Ferguson3,Gillian Smith1
1University of Dundee,2Bioinformatics and Biostatistics Service, Cancer Research UK,3NHS Tayside

AXL Mediates Resistance to AKT inhibition in Oesophageal Adenocarcinoma.

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Lauren Cairns1,Richard Turkington1,Leanne Stevenson1,Rosalie Douglas1,Nuala McCabe1,Richard Kennedy2,Timothy Harrison1
1Centre for Cancer Research and Cell Biology,2Centre for Cancer Research and Cell Biology

Organotypic cultures: a platform for assessing novel oncolytic therapy in solid tumours

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Marcos Kostalas1,Nicola Annels2,Guy Simpson2,Helen Saxby1,Nariman Karanjia1,Tim Worthington1,Rajesh Kumar1,Angela Riga1,Hardev Pandha2
1Royal Surrey County Hospital, Guildford,2University of Surrey

The Role of Vasculogenic Mimicry in Small Cell Lung Cancer

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Stuart Williamson1,Francesca Trapani2,Benjamin Abbott2,Robert Metcalf3,Melanie Galvin2,Fiona Blackhall3,Kristopher Frese2,Kathryn Simpson2,Caroline Dive2
1CRUK-Manchester Institute,2CRUK Manchester Institute,3The Christie NHS Foundation Trust

Circulating cell-free DNA analysis in limited and extensive stage small cell lung cancer

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Sumitra Mohan1,Mahmood Ayub1,Hui Sun Leong1,Sudhakar Sahoo1,Nigel Smith1,Barbara Mesquita1,Mathew Carter1,Lynsey Priest1,Crispin Miller1,Corinne Faivre-Finn2,Fiona Blackhall2,Dominic Rothwell1,Caroline Dive1,Ged Brady1
1Cancer Research UK Manchester Institute,2Christie NHS Foundation Trust, Institute of Cancer Sciences, The University of Manchester

Identification of MCAM (CD146) as galectin-3 binding ligand responsible for galectin-3-mediated endothelial secretion of metastasis-promoting cytokines.

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Florent Colomb1,Deborah Simpson1,Paulina Sindrewicz1,Jonathan Rhodes1,Rob Beynon1,Lu-Gang Yu1
1University of Liverpool

Molecular analysis of circulating free nucleic acids and CTC genomes in patients with pancreatic adenocarcinoma

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Mahmood Ayub1,Sakshi Gulati1,Sumitra Mohan1,Dominic Rothwell1,Hui Sun Leong1,Jakub Chudziak1,Sudhakar Sahoo1,Nigel Smith1,Barbara Mesquita1,Jenny Antonello1,Kyaw Aung2,Angela Lamarca3,Alison Backen3,Mairead McNamara3,Crispin Miller1,Juan Valle3,Caroline Dive1,Ged Brady1
1CRUK Manchester Institute,2Unniversity of Toronto,3Christie NHS Foundation Trust, Manchester

The role of aspartate metabolism in hypoxic breast cancer cells

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Fiona Grimm1,Dimitrios Anastasiou1
1The Francis Crick Institute

The circulating galactoside-binding proteins endothelial secretion of cytokines in cancer

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Weikun Wang1,Jonathan Rhodes1,Lu-gang Yu1
1University of Liverpool

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