5 abstracts found.



Results filter

BACR/AstraZeneca Young Scientist Frank Rose Award: Polyubiquitylaton drives replisome disassembly at the termination of eukaryotic DNA replication

Year:

Session type: ,

Agnieszka Gambus1

1University of Birmingham, UK


Introduction: genome instability: bench to bedside

Year:

Session type: ,


Targeting DNA repair in cancer treatment

Year:

Session type: ,

Thomas Helleday1

1Karolinska Institute, Stockholm, Sweden


Therapeutic Implications of DNA repair defects in Metastatic Prostate Cancer

Year:

Session type: ,

Johann de Bono1,2

1The Institute of Cancer Research, London, UK,2Royal Marsden, London, UK


Exploiting synthetic lethality to kill H3K36me3-deficient cancers by WEE1 inhibition

Year:

Session type: ,

Theme:

Sophia X Pfister1,Enni Markkanen1,Yanyan Jiang1,Sovan Sarkar1,Mick Woodcock1,Chen-Chun Pai1,Lykourgos-Panagiotis Zalmas1,Giulia Orlando1,Neele Drobnitzky1,Grigory Dianov1,Songmin Ying3,Nicholas B La Thangue2,Vincenzo DÂ’Angiolella1,Anderson Ryan1,Timothy C Humphrey1

1CRUK MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, OX3 7DQ, UK, Oxford, UK,2Laboratory of Cancer Biology, Department of Oncology, University of Oxford, Oxford, OX3 7DQ, UK, Oxford, UK,33Department of Respiratory and Critical Care Medicine of the Second Affiliated Hospital, and Department of Pharmacology, Zhejiang University School of Medicine, Hangzhou 310058, China., Hangzhou, China