Construction and characterisation of novel fusion toxin targeted to cancer (DT-SCF)


Session type:

Sirisha Potala, Rama Verma

Indian Institute of Technology Madras, Tamil Nadu, India


Fusion toxins, an emerging class of targeted therapies, exhibit remarkable tumour specificity thus promising a better alternative to current therapies in treatment of cancers. The aim of this study was to evaluate the cytotoxicity and specificity of a novel fusion toxin, diphtheria toxin-stem cell factor (DT-SCF).