Epidemiology of bladder cancer in Setif, Algeria


Year:

Session type:

Z. Zaidi1, A. Saada2, A. Dib2, D. Abdellouche3, A. DjemaDjazia4, M. Abdoun1, S. Laouamri1, A. Mahnane1, M. Hamdi Cherif1
1Cancer Registry of Setif- University Hospital of Setif, Setif, Algeria,2Department of Urology - University Hospital of Setif, Setif, Algeria,3Anatomopathology department - University Hospital of Setif, Setif, Algeria,4Constantine Anti-cancer center- University Hospital of Constantine, Constantine, Algeria

Background

Bladder cancer is the ninth most common cancer among men worldwide. It accounts for an estimated 330,000 cases and 130,000 deaths in the word.

With 141 new cases in Setif in 2005, bladder cancer is ranked fifth among men in the cancer registry of Setif and represents 5.9% of all cancers.

Our study aimed for adjusting bladder cancer incidence trends over the longest period available 1986-2005 in Setif for the effect of age, sex, and period of diagnosis and the geographical distribution. These data are compared with standardized rates of Cancer Registries in five continents.

Method

Incidence datas were collected in the period 1986-2005 from the population-based cancer registry of Setif, the software used is the Can Reg 4 from the International Agency for Research on Cancer IARC, France. Cancer morphology and topography are coded in accordance of the international classification of diseases for oncology manual (ICD-O, the third edition).

Results

At these two decades, age-adjusted incidence rate increased quickly from 2.2 per 100,000 men in 1986-1989 to 8.7 per 100,000 men 2001-2005.

Incidence was highest among men 70-74 age group (54%). The median age at diagnosis was 65-69 age group. Urologic cancers represent 16,7 % of all cancers.

Conclusion

The most important risk factor for bladder cancer is cigarette smoking which is thought to account for approximately 66% of new cases in men and 30% of cases in women in industrialized populations.

Like the lung cancer, this evolution was due to demographic changes and an increase in the risk factors of cancer during this period 1986-2005.

In Setif, Algeria, an increase in tobacco consumption with an increasing prevalence from 7.7% in 1978 to 28.6% in 2005 is paralleled by an increase in the incidence of bladder cancer. Tobacco control is the main tool in the fight against lung cancer.