Introduction: genome instability: bench to bedside


Targeting DNA repair for treatment of cancer has high future potential, extending also beyond inherited breast and ovarian cancers. This session focusses on novel translational strategies for targeting cancer more widely using DNA repair inhibitors with focus on real advances in patients and novel general approaches. The is important to clinicians seeking novel approaches for treatment of cancer and a scientists looking for new approaches for translating their work into real patient benefits. Learning objectives: 1. Endogenous DNA damage can be exploited in cancer 2. The synthetic lethal concept and going beyond inherited mutations