Abstract

This session is aimed at translational and basic scientists together with clinical, medical and surgical oncologists. A multidisciplinary approach is essential to decipher and manage intratumour heterogeneity solid and haematological malignancies, a disease with excessive genomic instability and mutational diversity. Speakers will review the genetic diversity within individual cancer subtypes and novel scientific, medical and informatics approaches to monitor genomic changes over space and time. The impact of our improving knowledge on clinical trial design and deciphering drug resistance mechanisms will be a central focus of this session.