Introduction: Clinical application of translational research in breast cancer


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John Yarnold1
1The Institute of Cancer Research, London, UK

Abstract

The session will take a step back from the direct clinical application of radiotherapy research and provide three internationally renowned speakers who will each address an area in which the biology of breast cancer is being explored and where there is optimism for translational research having a significant impact on clinical management.
Professor Adrian Harris will discuss changes in metabolic pathways in tumours, brought about by genetic lesions, and
the sort of approaches that are being investigated to exploit these changes for treatment. This will be followed Professor Doug Easton revealing how deep gene sequencing might come in the future, influencing how breast cancer is managed and how personalised medicine may become a reality. Finally Dr Nicolas Turner will present data, and his thoughts on its application to oncology in the emerging new targeted therapies for patients with advanced breast cancer.