Isoindolinone inhibitors of the MDM2-p53 protein-protein interaction: structure-activity studies


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Anna Watson, Eric Valeur, Bernard Golding, Roger Griffin, Claire Hutton, Jungfeng Liu, Xiaohong Lu, John Lunec, David Newell, Ian Hardcastle

Northern Institute for Cancer Research, Newcastle upon Tyne, UK

Abstract

Isoindolinone inhibitors of the MDM2-p53 protein-protein interaction: structure-activity studies