Refractory breathlessness: Mechanisms and management


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Miriam Johnson1
1Hull York Medical School, York, UK

Abstract

Chronic daily breathlessness, persistent despite optimal cancer treatment, is difficult for the patient, carer and clinician, resulting in a sense of therapeutic helplessness. However, there is a growing evidence base in our understanding of the impact and meaning of breathlessness for patients and carers, and for the effectiveness of pharmacological and non-pharmacological interventions.

This session will present key aspects of patient experience and the state of the art evidence base for pharmacological interventions (opioids, oxygen) and for complex non-pharmacological interventions. It will also highlight the importance of concurrent basic science research to elucidate mechanisms, thus identify further therapeutic targets.