153 abstracts found.



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Multiregion copy number analysis reveals Wilms’ tumour genetic heterogeneity

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George Cresswell1,Borbala Mifsud1,John Apps2,3,Richard Williams2,3,Oystein Olsen3,Kathy Pritchard-Jones2,3,William Mifsud2,3,Nicholas M. Luscombe1

1The Francis Crick Institute, London, UK,2UCL Institute of Child Health, London, UK,3Great Ormond Street Hospital, London, UK


Young patients with HER2+ breast cancer rarely have a germline mutation in a known cancer predisposition gene

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Diana Eccles1,Li Na2,Tom Maishman1,Ellen Copson1,Ian Campbell2

1University of Southampton, Southampton, UK,2Peter Macallum Cancer Centre, Melbourne, Australia


Longitudinal single cell clonal analysis reveals evolutionary stasis and predetermined malignant potential in non-dysplastic Barrett’s Oesophagus

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Pierre Martinez1,Margriet R. Timmer2,Chiu T. Lau2,Sybren L. Meijer2,Fiebo J.W. ten Kate2,Rosalie C. Mallant-Hent3,9,Anton H.J. Naber4,9,Arnoud H.A.M. van Oijen5,9,Lubbertus C. Baak6,9,Pieter Scholten7,9,Clarisse J.M. Böhmer8,9,Paul Fockens2,Jacques J.G.H.M. Bergman2,9,Carlo C. Maley10,11,Trevor A. Graham1,Kausilia K. Krishnadath2,9

1Barts Cancer Institute – Queen Mary University of London, London, UK,2Academic Medical Center – University of Amsterdam, Amsterdam, The Netherlands,3Department of Gastroenterology and Hepatology, Flevoziekenhuis, Almere, The Netherlands,4Department of Gastroenterology and Hepatology, Tergooiziekenhuizen, Hilversum, The Netherlands,5Department of Gastroenterology and Hepatology, Medisch Centrum Alkmaar, Alkmaar, The Netherlands,6Department of Gastroenterology and Hepatology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands,7Department of Gastroenterology and Hepatology, Sint Lucas Andreas Ziekenhuis, Amsterdam, The Netherlands,8Department of Gastroenterology and Hepatology, Spaarne Ziekenhuis, Hoofddorp, The Netherlands,9Gastroenterological Association, Amsterdam, The Netherlands,10Center for Evolution and Cancer, University of California at San Francisco, San Francisco, CA, USA,11Biodesign Institute, School of Life Sciences, Arizona State University, Tempe, AZ, USA