405 abstracts found.



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Inhibition of the pro-tumorigenic effects of TGFbeta in tumor therapy

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Carl-Henrik Heldin1
1Uppsala University

Deregulated TGF-β signalling in cancer

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Caroline Hill1
1The Francis Crick Institute

Role of TGF-beta in glioblastoma

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Joan Seoane1
1Vall d'Hebron University Hospital

Role of the gut microbiome in causing, detecting and treating coloretal cancer.

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Paul O'Toole1
1School of Microbiology and APC Microbiome Inst

Impact of patient’s gut microbiome on clinical reponse to cancer immunotherapy

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Robert Jenq1
1University of Texas MD Anderson Cancer Center

The burden of cancer due to inequalities and its likely causes – Introduction

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Yoryos Lyratzopoulos1
1University College London

Learning from research on cancer disparities in the US

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Nancy Keating1
1Harvard Medical School

Social inequalities in cancer screening participation

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Jo Waller1
1University College London

The role of individual and system factors on inequalities in cancer care and outcomes

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Bernard Rachet1
1London School of Hygiene and Tropical Medicine

Tumour microenvironment and radiation – friend or foe?

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Kaye Williams1
1University of Manchester

DNA damage repair inhibitors and radiation- are normal tissues spared?

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Susan Short1
1University of Leeds

The challenges of rare cancer: Time for change

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Richard Adams1
1Cardiff University

Designing trials in smaller populations

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Matthew Sydes1
1MRC Clinical Trials Unit at UCL

Core Outcomes Sets for trials and Core Information Sets for consultations: keeping them patient centred

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Jane Blazeby1,Angus McNair1
1University of Bristol

Best practices for integration of Patient-Reported Outcomes (PROs) into trials

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Derek Kyte1
1University of Birmingham

Discovery of potent, selective and orally bioavailable CDK8/CDK19 kinase modulators

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Aurélie Mallinger,1 Kai Schiemann,2 Christian Rink,1 Frank Stieber,2 Simon Crumpler,1 Mark Stubbs,1 Olajumoke Adeniji-Popoola,1 Oliver Poeschke,2 Michael Busch,2 Paul Czodrowski,2 Djordje Musil,2 Daniel Schwarz,2 Maria-Jesus Ortiz-Ruiz,1 Richard Schneider,2 Melanie Valenti,1 Alexis de Haven Brandon,1 Rosemary Burke,1 Paul Workman,1 Trevor Dale,3 Dirk Wienke,2 Paul Clarke,1 Christina Esdar,2 Florence Raynaud,1 Suzanne Eccles,1 Felix Rohdich2 and Julian Blagg1

1The Institute of Cancer Research, London 2Merck KGaA, Darmstadt, Germany 3School of Bioscience, Cardiff University


Focal Adhesion Kinase – a new target in cancer immunotherapy

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Alan Serrels1

1MRC Centre for Inflammation Research, Queen’s Medical Research Institute, University of Edinburgh


R-spondin gain-of-function in colorectal cancer – a comparison between mature tumours and precursor polyps

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Sam Kleeman1,Roland Arnold1,on behalf of S-CORT Consortium2,Tim Maughan3,Simon Leedham1
1Wellcome Trust Centre for Human Genetics,2S-CORT Consortium,3CRUK/MRC Oxford Institute for Radiation Oncology

Web-based system to monitor cancer patients’ physical symptoms during active treatment-engaging patients and clinicians

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Galina Velikova1
1University of Leeds

Patient-reported outcomes for adverse event and symptom monitoring in oncology

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Ethan Basch1
1University of North Carolina at Chapel Hill

Challenges and opportunities for quality of life and symptom assessment in cancer clinical trials

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Melanie Calvert1
1University of Birmingham

EORTC Perspectives on QOL in clinical trials

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Andrew Bottomley1
1EORTC

Advances in the measurement of patient-reported outcomes

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John Ware1
1University of Massachusetts Medical School

WNT signalling and the Mediator complex associated kinases CDK8/19

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Julian Blagg1
1The Institute of Cancer Research

Fixation and spread of somatic clones in adult human colon

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Anna Nicholson1
1Cancer Research UK

Different smoking cessation options and their effectiveness, including Stop Smoking Services and e-cigarettes

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Leonie Brose1
1King's College London

Epidemiological research showing that tobacco use is the largest preventable cause of cancer – including types of cancer beyond just lung cancer

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Kamran Siddiqi1
1University of York

From CRISPR-Cas9 drop-out screens to novel therapeutic approaches in acute myeloid leukaemia

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George Vassiliou1
1Wellcome Trust Sanger Institute

Modelling cancer in human stem cell organoid cultures

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Jarno Drost1
1Princess Máxima Centre for Paediatric Oncology

Heterocellular interaction in the tumour microenvironment

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Claus Jorgensen1
1CRUK Manchester Institute

Antigen discovery in long term pancreatic cancer survivors

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Vinod Balachandran1
1Memorial Sloan-Kettering Cancer Center

Functional Magnetic Resonance Imaging (MRI) for assessing response to Radiotherapy

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Nandita deSouza1
1The Institute of Cancer Research

1.5T MRI-linac: bringing sight to the radiotherapy treatment

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Bas Raaymakers1
1UMC Utrecht

Care of dying people: Why, how and what?

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Bee Wee1
1University of Oxford

Innovations in AYA Care from North America

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Rebecca Johnson1
1Mary Bridge Hospital, Tacoma, Washington

Understanding the barriers to recruitment of teenagers and young adults with cancer to research

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Rachel M Taylor1,Charlotte Kenten1,Ana Martins1,Lorna Fern2,Faith Gibson3,Sarah Lea2,Nothando Ngwenya1,Jeremy S Whelan1
1University College London Hospitals NHS Trust,2,3University of Surrey

CART cell immunotherapy for lymphoma

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Karl Peggs1
1UCL Cancer Institute

Introducing targeted therapies into lymphoma management

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Graham Collins1
1Oxford University Hospitals NHS Foundation Trust

Targeting stem cells in colorectal cancer

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Felipe de Sousa e Melo1
1Roche

Mechanical guidance of collective cell invasion

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Xavier Trepat1
1Institute for Bioengineering of Catalonia

Carcinoma-associated fibroblasts exert mechanical forces on the basement membrane to help cancer cell invasion

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Danijela Matic Vignjevic1
1Institut Curie

Vitamin D and colon cancer survival: What can we learn from MPE studies?

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Helen Coleman1
1Queen's University Belfast

Molecular pathological epidemiology of colorectal cancer in the Netherlands Cohort Study and Rainbow-TMA

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Piet van den Brandt1
1Maastricht University

Emerging topics in MPE: Integration of immunology and microbiology

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Shuji Ogino1
1Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Harvard T.H. Chan School of Public Health

The developmental transcription factor ELF3 is critical for lung tumourigenesis

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Katey Enfield1,Erin Marshall1,Kevin Ng1,Christine Anderson1,Aly Karsan1,Igor Jurisica2,Wan Lam1
1British Columbia Cancer Research Centre,2Princess Margaret Cancer Centre

The use of tool compounds to validate and invalidate oncology targets

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Nicola Wallis1
1Astex Therapeutics

The clinical applications of multi-parametric MRI for radiotherapy planning and treatment

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Roberto Alonzi1
1Mount Vernon Cancer Centre

Stromal/leukocyte crosstalk in immunity and tumour progression

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Sophie Acton1
1University College London

Developing immune stratification for cancer: targeting the tumour microenvironment

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Gareth Thomas1
1University of Southampton

Integration of validated protein biomarkers within Molecular Pathology Diagnostic Service: the challenges

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Phillippe Taniere1
1University Hospital Birmingham