6719 abstracts found.



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The incidence of non-ovarian cancers in women with elevated CA125 levels in General Practice

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Garth Funston1,Willie Hamilton2,Gary Abel2,Emma Crosbie3,Brian Rous4,Fiona Walter5

1Department of Public Health and Primary Care, University of Cambridge,2University of Exeter,3Gynaecological Oncology Research Group, Division of Cancer Sciences, University of Manchester,4National Cancer Registration and Analysis Service, Public Health England,5Department of Public Health and Primary Care, University of Cambridge, Cambridge

Non-invasive methylation test to detect cervical pre-cancer in self-collected vaginal and urine specimens

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Belinda Nedjai1,Caroline Reuter1,Toni Hollingworth1,Janet Austin1,Louise Cadman1,Jack Cuzick1,Attila Lorincz1

1Queen Mary University of London, London, UK

Prospective clinical validation of novel serum biomarker test for the identification of patients at risk of brain tumour.

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Paul Brennan1,Holly Butler2,Mark Hegarty3,Ben Smith2,David Palmer2,Michael Jenkinson4,Matt Baker5

1university of edinburgh,2University of Strathclyde,3Clin Spex Dx Ltd,4University of Liverpool,5university of Strathclyde

Difficulties In Providing Palliative Care In Rural India (West Bengal) – Experience Of An NGO

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Nabanita Mandal1,Aditya Manna2
1Narikeldaha Prayas,2MAS Clinic & Hospital

CT Scan to Screen for Occult Cancer in Unprovoked Venous Thromboembolism (VTE)

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CHUN WAI Wong1,Kelly Lim1,Rachel Garnett1,Harris Khan1,Faisal Solkar1,Shahab Abbas1
1ROYAL STOKE UNIVERSITY HOSPITAL

Decision regret in men living with and beyond non-metastatic prostate cancer in the UK: Results from the Life After Prostate Diagnosis study

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Sarah Wilding1,Amy Downing1,Peter Selby1,William Cross2,Penny Wright1,Eila K Watson3,Richard Wagland4,Paul Kind1,David W Donnelly5,Luke Hounsome6,Rebecca Mottram1,Majorie Allen1,Therese Kearney5,Hugh Butcher1,Anna Gavin5,Adam W Glaser1
1University of Leeds,2Leeds Teaching Hospitals,3Oxford Brookes University,4University of Southampton,5Queen's University Belfast,6Public Health England

Yeast orthologue mapping predicts genetic vulnerabilities in tumour cells

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Mark Wade1,Kaliya Georgieva2,Christopher Hindley1,Harpreet Saini1
1Astex Pharmaceuticals,2University of Bath

The impact of dietetic input in post radiotherapy head and neck cancer patients

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Robynne Cranston1,Nola Lynch1,Isobel Bowe1,Charles Kelly2,Shahid Iqbal2,Rachel A Pearson3
1Nutrition and Dietetics Department, Freeman Hospital, NHS Newcastle upon Tyne Hospitals, Newcastle upon Tyne, UK,2Northern Centre for Cancer Care, Freeman Hospital, Newcastle upon Tyne, UK,3 Northern Centre for Cancer Care, Freeman Hospital, Newcastle upon Tyne, UK, Newcastle University, Newcastle upon Tyne, UK

Evaluating kinome-wide resistance mechanisms to 3rd generation EGFR inhibitors

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Emma Fairweather1,Patrick Eyers1
1University of Liverpool

PanCO: An Open-Label, Single-Arm Pilot Study of Phosphorus-32 Microparticles in Unresectable Locally Advanced Pancreatic Adenocarcinoma with FOLFIRINOX or Gemcitabine + Nab-Paclitaxel Chemotherapies

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Paul Ross1,Natalie Phillips2,Zarni Win2,Christopher Wadsworth2,Thankamma Ajithkumar3,Luigi Aloj3,Edmund Godfrey3,Chinenye Iwuji4,Rakesh Ganatra4,Sudarshan Kadri4,Marion Harris5,Daniel Croagh5,Morteza Aghmesheh6,Adnan Nagrial7,Nam Nguyen8,Mehrdad Nikfarjam9,Alain Hendlisz10,Thomas Maher11,Anna Kraszewski11,Harpreet Wasan2
1Guy's & St Thomas' NHS Foundation Trust, London, UK,2Imperial College Healthcare NHS Trust, London, UK,3Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK,4University Hospitals of Leicester NHS Trust, Leicester, UK,5Monash Health, Melbourne, Australia,6Southern Medical Day Care Centre, Wollongong, Australia,7Westmead Hospital, Sydney, Australia,8Royal Adelaide Hospital, Adelaide, Australia,9Austin Health, Melbourne, Australia,10Institut Jules Bordet Université Libre de Bruxelles, Brussels, Belgium,11OncoSil Medical Ltd., Sydney, Australia

PRIMUS 002: An umbrella phase II study examining two neo-adjuvant regimens (FOLFOX-A and AG) in resectable and borderline resectable Pancreatic Ductal AdenoCarcinoma (PDAC)

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Derek Grose1,Colin McKay2,Nigel Jamieson3,Janet Graham1,David McIntosh1,Fraser Duthie3,Ganesh Radhakrishna4,Dave Colville1,Aileen Dufton1,Peter Houston1,Maria Hawkins5,Rebecca Goody6,Reena Ravikumar7,James Paul8,Jamie Stobo8,Susie Cooke3,Sarah Bradley8,Judith Dixon-Hughes3,Andrew Biankin3,David Chang3
1Beatson West of Scotland Cancer Centre,2West of Scotland Pancreatic Unit, Glasgow Royal,3University of Glasgow,4University of Manchester, Division of Cancer Sciences,5CRUK MRC Oxford Institute for Radiation Oncology,6Leeds Teaching Hospitals NHS Trust,7King’s College Hospital, London,8CRUK Clinical Trials Unit, Institute of Cancer Sciences, University of Glasgow

A predictive model to estimate the probability of EGFR mutation(s) in New Zealand patients with non-squamous NSCLC

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Phyu Aye1,Sandar Tin Tin1,Mark McKeage1,Prashannata Khwaounjoo1,Arier Lee1,Alana Cavadino1,Mark Elwood1
1The University of Auckland

MAESTRO/PERSEUS: A phase II molecular stratification/treatment platform in Metastatic Castration Resistant Prostate Cancer (mCRPC) – PERSEUS1 (pembrolizumab; NCT03506997)

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Pasquale Rescigno1,Stephanie Burnett1,Nuria Porta1,Ajit Sarvadikar1,Penelope Flohr1,Ines Figueiredo1,Diletta Bianchini2,Suzanne Carreira1,Ruth Riisnaes1,Susana Miranda1,Mateus Crespo1,Bora Gurel1,Maryou B. Lambros1,Claudia Bertan1,Matthew Clarke1,George Seed1,Ana Ferreira1,Ana Rita da Silva Pereira1,Emma Hall1,Johann de Bono2
1The Institute of Cancer Research,2The Institute of Cancer Research & The Royal Marsden NHS Foundation Trust

Exploring estrogen receptor(ER)+ve breast cancer survivors’ and health care professionals’ views and experiences of weight management(physical activity and nutrition) before, during and post treatment

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Katie Pickering1,Sarah Wane2,Helen Crank1,Annie Anderson3,Janet Brown4,Henry Cain5,Rob Copeland1,Kate Kendell5,Daniela Lee5,Peter McMeekin2,Richard McNally6,Laura Thomas7,Caroline Wilson8,John Saxton2
1Sheffield Hallam University,2Northumbria University,3University of Dundee,4University of Sheffield,5Newcastle Upon Tyne NHS Trust,6Newcastle University,7Liverpool John Moores University,8University of Sheffield and Sheffield Teaching Hospitals NHS Foundation Trust

Immune-related hypophysitis: a tertiary referral centre experience

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Ionut-Gabriel Funingana1,Sarah Welsh1,Benjamin Devoy1,Christine Parkinson1,Krishna Chatterjee1,Pippa Corrie1
1Cambridge University Hospitals NHS Foundation Trust

Accurate targeted long-read DNA methylation sequencing with TAPS.

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Yibin Liu1,Yibin Liu1,Jingfei Cheng1,Paulina Siejka-Zielinska1,Chunxiao Song1
1University of Oxford

Assessment and monitoring of cardiotoxicity in Breast Cancer patients treated with  HER2-directed Agents (Trastuzumab, Pertuzumab, and Ado-trastuzumab emtansine (T-DM1)

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Sudha Karanam1,Mariam Jafri1,Daniel Rea1,Nyein Su Tun1
1University Hospital Birmingham NHS Trust

Investigating the interaction between phosphodiesterase 4D7 (PDE4D7) and DHX9 in the progression of prostate cancer

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Tara Busiau1,Jane Finlay1,Joanne Edwards1,Ralf Hoffman2,George Baillie1
1University of Glasgow,2Philips Diagnostics

The road to personalised anticancer therapy: utilizing the LAT1 transporter as a selective mode of iron deprivation

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Gina Abdelaal1,Kyriakou Sotirus1,David Tetard1,Stephany Veuger1
1Northumbria University

Outcomes following critical illness among cancer patients: A population-based observational study using a matched comparison group.

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Mae-Yen Tan1,Philip McLoone1,Billy Sloan1,Tara Quasim1,Kathryn Puxty1,David Morrison1
1University of Glasgow

Exploiting the metabolic vulnerabilities imposed by glucocorticoids for glioblastoma treatment

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Maria Francesca Allega1,Victor Villar Cortes2,David Sumpton2,Gillian Mackay2,Saverio Tardito2
1Beatson Institute for Cancer Research,2Cancer Research UK Beatson Institute

A potent synergy between FOXG1 overexpression and Wnt signaling drives cell cycle re-entry in quiescent glioblastoma stem cells

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Faye Robertson1,Eoghan O'Duibhir1,Harry Bulstrode2,Steve Pollard1
1University of Edinburgh, Edinburgh, UK,2University of Cambridge, Cambridge, UK

Resveratrol’s effects on a BRAF mutant mouse model of colorectal carcinogenesis

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Grandezza Aburido1,Hong Cai1,Raj Singh1,Don Jones1,Rob Britton1,Karen Brown1
1University of Leicester

Top Ten Research Priorities in Cancer Early Detection: a priority setting partnership between patients and healthcare professionals

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Ellena Badrick1,Andrew Renehan1,Gen Buckley2,Lindsey Brown2,Katharine Cresswell,3,Phil Crosbie1,Clare Dickinson4,Patricia Elis5,Peter Hall6,James Leighton7,David Makin2,Lee Malcomson4,Richard Martin8,Rebecca Morris1,Helena O’Flynn9,Emma Thorpe4,Emma Crosbie1
1University of Manchester,2Public Contributor,3Manchester Foundation Trust,4Christie Hospital,5James Lind Alliance,6University of Edinburgh,7Greater Manchester Cancer,8University of Bristol,9NHS

Real world treatment sequencing patterns in secondary breast cancer (SBC): Pathway visualisation using national datasets.

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Ashley Horne1,Maria McMenemy2,Holly Ennis3,Lauren Murdoch3,Grace Ding1,Olga Oikonomidou1,Caroline Michie1,Larry Haywood1,David Cameron1,Christina Lilley1,Peter Hall4,Alison Stillie1,Aisling Hennessy1,Frances Yuille1
1Edinburgh Cancer Centre, Western General Hospital, Edinburgh, UK,2Lothian Analytical Services, NHS Lothian, Edinburgh, UK,3Edinburgh Clinical Trials Unit, University of Edinburgh, Edinburgh, UK,4Edinburgh Cancer Research Centre, University of Edinburgh, Edinburgh, UK

Best supportive care (BSC) with or without low-dose chemotherapy (chemo) in frail elderly patients with advanced gastroesophageal cancer (aGOAC): The uncertain randomization of the GO2 phase III trial

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Daniel Swinson1,Peter Hall2,Mohan Hingorani3,Zuzani Stokes4,Jo Dent5,Kamalnayan Guptal6,Anirban Chatterjee7,Konstantinos Kamposioras8,Simon Aird Grumett9,Mohammad Khan10,Helen Marshall11,Ruddock Sharon11,Cairns David11,Christine Allmark12,Eszter Katona11,Helen C Howard11,Galina Velikova13,Simon Lord14,Matthew T Seymour15
1St James's University Hospital, Leeds, UK,2University of Edinburgh, Edinburgh.,3St James's University Hospital, Leeds.,4Lincolnshire Hospitals, Lincoln,5Calderdale and Huddersfield Royal Infirmary,6Worcester, United Kingdom,7Shrewsbury & Telford Hospitals, Shrewsbury,8Christie Hospital, Manchester,9Royal Wolverhampton Hospitals, Wolverhampton,10Scarborough Hospital, Scarborough,11CTRU, University of Leeds, Leeds,12NCRI Consumer Forum, London,13University of Leeds, Leeds,14University of Oxford, Oxford,15National Institute for Health Research Clinical Research Network, Leeds, United Kingdom

“I thought there would have been pain” A qualitative investigation of patients’ experiences of the route to, and diagnosis of, head and neck cancer.

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Jennifer Deane1,Joanne Patterson1,Linda Sharp1
1Newcastle University

Assessing Food Related Anxiety in patients with Lung Cancer

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Iain Phillips1,Hannah Appleton2,Zari Bhatti2,Angus Lawson2,Adam Tobias2,Juliet Tyndall2,Lucas Watson2,Colin Barrie3
1Royal Surrey County Hospital,2University of Edinburgh,3Edinburgh Cancer Centre, Western General Hospital, Edinburgh

Invasion by gut bacteria promotes growth in early and late stage colorectal tumour cells

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James Robson1,David Qualtrough1,Robin Thorn1
1University of the West of England

Longitudinal Changes in Fasting Blood Glucose and Cancer Risk in Chinese Population Without Diabetes

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Xiaoshuang Feng1,Gang Wang2,Zhangyan Lyu1,Shuohua Chen3,Luopei Wei1,Xin Li1,Yan Wen1,Yuheng Chen1,Shuanghua Xie1,Hong Cui1,Hongda Chen1,Jiang Li1,Chunqing Lin1,Jiansong Ren1,Jufang Shi1,Shouling Wu4,Min Dai1,Ni Li1,Jie He1
1National Cancer Center / National Clinical Research Center for Cancer / Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College,2Kailuan general hospital,3Health department of Kailuan Group,4Health Department of Kailuan Group

Invasive breast cancer over four decades reveals persisting poor metastatic outcomes in treatment resistant subgroup – the “ATRESS” phenomenon

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Patriek Jurrius1,Thomas Green1,Hans Garmo1,Matthew Young2,Massimilano Cariati1,Cheryl Gillett1,Anca Mera1,Mark Harries2,Anita Grigoriadis1,Sarah Pinder1,Lars Holmberg1,Arnie Purushotham1
1King's College London,2Guy’s and St Thomas NHS Foundation Trust

PARP inhibition causes replication stress in preclinical models of high risk neuroblastoma and synergises with inhibition of ATR

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Harriet Southgate1,Nicola J Curtin1,Deborah A Tweddle1
1Newcastle University, Newcastle, UK

Is pelvic examination a key part of a patient’s gynaecological cancer diagnostic journey? A qualitative study of GPs and specialists.

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Pauline Williams1,Maggie Cruickshank1,Christine Bond1,Christ Burton2,Peter Murchie1
1University of Aberdeen,2University of Sheffield

Survival outcomes in oropharyngeal cancer: a decision tree analysis

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Francesca De Felice1,Laia Humbert-Vidan2,Mary Lei2,Andrew King2,Teresa Guerrero Urbano2
1Guy's and St Thomas' NHS Foundation Trust, London, Sapienza University of Rome, Rome, Italy,2Guy’s and St Thomas’ NHS Foundation Trust, London, UK

Embracing the Digital Age in Oncology Outpatients. A Qualitative Study

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Pippa Bullard1,Catherine Sharma1,Claire Diver2
1Nottingham University NHS Trust,2University of Nottingham

Endocrinopathies in patients undergoing treatment with Immune Checkpoint Inhibitors at Royal Cornwall Hospital.

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Dhruv Abhi1
1Royal Cornwall Hospitals NHS Trust

A novel capillary nano-immunoassay towards rapid, quantitative measurement of cell cycle biomarkers in clinical trials

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Eleanor Tiplady1,Krishna Yalla1,Eilidh McCulloch1,Alan Bilsland1,Kathrin Heinzmann2,Fiona Thomson1
1University of Glasgow,2Cancer Research UK

Correlation of Cancer Stem Cell Markers ITGA6 and ALDH1 with Mammosphere Formation in Breast Cancer

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Kristin Manor1,Simon Timbrell2,Robert Clarke3,Nigel Bundred2
1University of Manchester,2University Hospital of South Manchester,3Manchester Breast Centre, Division of Cancer Sciences, University of Manchester

#BCSM and #breastcancer: Contemporary cancer-specific online social media communities

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James Platt1,Richard Brady2
1Newcastle upon Tyne Hospitals NHS Foundation Trust,2Newcastle Centre for Bowel Disease Research Group, Newcastle Upon Tyne Hospitals NHS Foundation Trust and Newcastle University, UK

Service evaluation of a weight management after cancer treatment programme

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Stuart Spear1,Rachel Bracegirdle1,Nicola Peat1
1Guy's and St Thomas' NHS Foundation Trust

The use of c-reactive protein in acute oncology admissions

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Kirsty Cavanagh1,Mark Baxter2,Ellie Dow3,Judith A Strachan4,Gillian Smith5,Michelle Ferguson6
1School of Medicine, University of Dundee, Ninewells Hospital & Medical School,2Division of Molecular & Clinical Medicine, School of Medicine, University of Dundee, Ninewells Hospital & Medical School,3Department of Clinical Biochemistry, Ninewells Hospital & Medical School,4Department of Blood Sciences, Ninewells Hospital & Medical School,5Division of Cellular Medicine, School of Medicine, University of Dundee, Ninewells Hospital & Medical School,6Tayside Cancer Centre, Ninewells Hospital & Medical School

Implications of physical activity on CPET in a prostate cancer sample – feasibility trial

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Luke Robles1,Lucy Hackshaw-McGeagh1,Claire M Perks1,Hilary Taylor1,Stephen Tolchard2,Edward Rowe3,Jonathon Aning3,Raj Persad3,Anthony Koupparis3,J Athene Lane1,Richard M Martin1
1University of Bristol,2North Bristol NHS Trust,3Bristol Urological Institute

Orbital Tumor Board: lifesaver or timewaster?

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Ayesha Butt1
1Aga Khan University Hospital

Cancer comorbidities and hospital admission: A Scottish Routes from Diagnosis analysis

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Emily Moore1,Cheryl Denny2,Kelly Sheil-Davis3,Clare Le Blanc3
1Information Services Division, NHS National Services Scotland, Edinburgh, UK,2Information Services Division,3MacMillan Cancer Support

A novel ProTide, NUC-7738, induces AMPK activation and cell death in both cell lines and ex vivo tissues of human renal cell carcinoma

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Mary Kudsy1,Mustafa Elshani1,Sarah Puthur1,Wen Chen1,In Hwa Um1,Grant D. Stewart2,Maeve Rahilly3,Alex Chapman3,Michelle Myers4,David J. Harrison1
1University of St Andrews,2University of Cambridge,3Victoria Hospital, NHS Fife,4Nucana

Understanding international variation in access to PET-CT for oncology diagnostics: An International Cancer Benchmarking Partnership (ICBP) study.

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Charlotte Lynch1,Irene Reguilon2,Deanna Langer3,Damon Lane4,Wai-Lup Wong5,Fergus McKiddie6,Andrew Ross7,Lorraine Shack8,Thida Win5,Christopher Marshall9,Mona-Elizabeth Revheim10,Bolette Danckert11,Sabina Dizdarevic5,Canice McGivern12,Anne Hazlett12,Cheryl Louzado13,Mark MacMillan8,Sam Harrison1
1Cancer Research UK, London, UK,2eConsult, London, UK,3Cancer Care Ontario, London, UK,4Pacific Radiology, New Zealand,5NHS England, London, UK,6NHS Grampian, Aberdeen, UK,7Canadian Association of Nuclear Medicine, Ottawa, Canada,8Alberta Health Services, Edmonton, Canada,9Wales Research and Diagnostic PETIC, Cardiff, UK,10Oslo University Hospital, Oslo, Norway,11Aarhus University, Aarhus, Denmark,12Belfast Health and Social Care Trust, Belfast, UK,13Canadian Partnership Against Cancer, Toronto, Canada

Delivery of radiotherapy clinical trials: Recommendations for best practice across Clinical Trial Units (CTU) and the National Radiotherapy Trials Quality Assurance Group (RTTQA)

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Lisette Nixon1,Elizabeth Miles2,Natalie Abbott3,Sue Bell4,Clare Cruickshank5,Patty Diez6,Alexandra Smith4,Yat Tsang6,Emma Hall5,on behalf of CTRad7
1Cardiff University, Cardiff, UK,2Coordinator National Radiotherapy Trials QA (RTTQA) Group, London, UK, Mount Vernon Cancer Centre, Northwood, UK,3Velindre Cancer Centre, Cardiff, UK,4University of Leeds, Leeds, UK,5The Institute of Cancer Research, London, UK,6Mount Vernon Cancer Centre, Northwood, UK,7National Cancer Research Institute, London, UK

Antiproliferation and anti-invasion of 1’-Acetoxychavicol acetate on hormonal-resistant breast cancer cells

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Nalinee Pradubyat1,Wannarasmi Ketchart2,Carlo Palmieri3,Athina Giannoudis4
1University of Liverpool,2Faculty of Medicine, Chulalongkorn University,3Institute of Translational Medicine, University of Liverpool, Clatterbridge Cancer Centre, UK,4Institute of Translational Medicine, University of Liverpool

An Analysis of Prognostic Biomarkers of the Systemic Inflammatory Response in Cancers of Unknown Primary

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Rebekah Patton1,Rebekah Patton1,Gillian Knowles1,Rachel Haigh1,Lucy Dobbs2,Barry Laird1,Colin Barrie1,Sally Clive1
1NHS Lothian, Edinburgh, UK,2University of Edinburgh, Edinburgh, UK

Exposure to ionizing radiation elicits significant lung tissue perturbations and creates a tumour-supportive microenvironment

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Emma Nolan1,Ilaria Malanchi1
1Francis Crick Institute