¹University of Edinburgh, Edinburgh, UK, ²Wyeth Research, Collegeville, USA

¹The University of Manchester, Manchester, UK, ²GlaxoSmithKline, London, UK

Imperial College, London, UK

¹Cancer Laboratory, Queen Alexandra Hospital, Portsmouth 1Cancer Laboratory, Queen Alexandra Hospital, Portsmouth PO6 3LY, UK, ²Moorfields Eye Hospital and Institute of Opthalmology (UCL), London EC1V 9EL, UK

¹Academic Unit of Oncology, School of Molecular Medical Sciences, University of Nottingham, Nottingham, UK, ²Division of Pathology, School of Molecular Medical Sciences, University of Nottingham, Nottingham, UK, ³Department of Pathology, Nottingham University Hospitals, Nottingham, UK, ⁴Division of Gastrointestinal Surgery, University of Nottingham, Nottingham, UK, ⁵Department of Surgery, Nottingham University Hospitals, Nottingham, UK

AstraZeneca, Loughborough, Leicestershire, UK

¹Cancer Research UK Clinical Trials Unit, Birmingham, UK, ²Medical Research Council Clinical Trials Unit, London, UK, ³Cookridge Hospital, Leeds, UK, ⁴New Cross Hospital, Wolverhampton, UK

¹Centre for Cancer and Inflammation, Institute of Cancer, Barts and The London School of Medicine and Dentistry, London, UK, ²Chemokine Therapeutics Corp, Vancouver, Canada

University of Manchester, Manchester, UK

¹Cancer Research UK Angiogenesis Group, The Institute for Biomedical Research, University of Birmingham Medical School, Edgbaston, Birmingham B15 2TT, UK, ²Angiogenesis Laboratory, Cancer Research UK, Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK, ³Cancer Research UK, The London Research Institute, Lincoln’s Inn Fields, London WC2A 3PX, UK

¹Centre for Cancer and Inflammation, Institute of Cancer and the Cancer Research UK Clinical Centre, Barts and The London School of Medicine and Dentistry, London, UK, ²Sir William Dunn School of Pathology, University of Oxford, Oxford, UK

University of Manchester, Manchester, UK

University of Edinburgh, Edinburgh, UK

¹Radiation Oncology and Biology Institute, Oxford, UK, ²Gray Cancer Institute, Northwood, UK, ³Health Protection Agency, Centre for Radiation, Chemical and Environmental Hazards, Chilton, UK, ⁴Royal Marsden Hospital and Institute of Cancer Research, Sutton, UK

¹MRC Human Reproductive Sciences Unit, Edinburgh, UK, ²Edinburgh Breakthrough Research Unit, Edinburgh, UK

University of Oxford, Oxford, UK

Newcastle University, Newcastle upon Tyne, UK

Open University, Milton Keynes, UK

¹Max-Planck Institute for Molecular Genetics, Berlin, Germany, ²Institute of Biochemistry and Center for Molecular Biosciences, Innsbruck, Austria, ³Ninewells Hospital, Department of Neuroscience and Pathology, Dundee, UK

University of York, York, UK

¹Università degli Studi di Milano, Milan, Italy, ²Istituto Nazionale Tumori, Milan, Italy, ³Istituto Mario Negri, Milan, Italy, ⁴Göteborg University, Göteborg, Sweden

University of Oxford, Oxford, UK

Queen's University Belfast, Belfast, UK

Oxford University, Oxford, UK

Imperial College London, Div. Investigative Sciences, London, UK

Université de Sherbrooke, Quebec, Canada

¹Imperial College London, London, UK, ²Cancer Research UK - London research Institute, London, UK

University of Birmingham, Birmingham, UK

University of Birmingham, Medical School, Institute for Biomedical Research, Division of Immunity and Infection, Birmingham, West Midlands, UK

¹Ludwig Institute for Cancer Research, London, UK, ²Almac Diagnostics, Northern Ireland, UK, ³The Breakthrough Breast Cancer Research Centre, London, UK, ⁴Institute of Neurology, London, UK

University of Leicester, Leicester, UK

University of Sheffield, Sheffield, South Yorkshire, UK

Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan

CCRCB Quenns University, Belfast, Northern Ireland, UK

Gray Institute for Radiation Oncology and Biology, University of Oxford, Oxford, UK

¹University of Birmingham, Birmingham, UK, ²Birmingham City Hospital, Birmingham, UK

Cancer Research UK, Cambridge, UK

¹MRC Dunn Human Nutrition Unit, Cambridge, UK, ²University of Oslo, Oslo, Norway

Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, UK

Department of Diagnostic Sciences and Special Therapy, University of Padova, Padova, Italy

¹Cancer Research UK, London, UK, ²The Scripps Research Institute, La Jolla, CA, USA

Centre for Tumour Biology, Cancer Research-UK Clinical Centre, Bart's and The London, London, UK

¹University of Birmingham, Birmingham, UK, ²The Beatson Institute for Cancer Research, Glasgow, UK

Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK

¹Tumour Targeting Group, University of Sheffield Medical School, Sheffield, South Yorkshire, UK, ²Dept Oral and Maxillofacial Surgery, School of Clinical Dentistry, Sheffield, South Yorkshire, UK

Queen Mary's School of Medicine and Dentistry, Centre for Cancer and Inflammation, London, UK

Cancer Research UK, London Research Institute, London, UK

University of Guilan, Rasht, Iran

¹Cancer Research UK Renal Molecular Oncology Group, University of Birmingham, Birmingham, UK, ²Paterson Institute for Cancer Research, University of Manchester, Manchester, UK, ³Yokohama City University School of Medicine, Yokohama, Japan

Cancer Epidemiology Unit, University of Oxford, Oxford, UK