6719 abstracts found.



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Delivery of radiotherapy clinical trials: Recommendations for best practice across Clinical Trial Units (CTU) and the National Radiotherapy Trials Quality Assurance Group (RTTQA)

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Lisette Nixon1,Elizabeth Miles2,Natalie Abbott3,Sue Bell4,Clare Cruickshank5,Patty Diez6,Alexandra Smith4,Yat Tsang6,Emma Hall5,on behalf of CTRad7
1Cardiff University, Cardiff, UK,2Coordinator National Radiotherapy Trials QA (RTTQA) Group, London, UK, Mount Vernon Cancer Centre, Northwood, UK,3Velindre Cancer Centre, Cardiff, UK,4University of Leeds, Leeds, UK,5The Institute of Cancer Research, London, UK,6Mount Vernon Cancer Centre, Northwood, UK,7National Cancer Research Institute, London, UK

The association between palliative healthcare service provision and place of death: a population study of cancer patients

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Maria Kelly1,Katie O' Brien1,Ailish Hannigan2
1National Cancer Registry Ireland,2University of Limerick

Digital questionnaires to help determine a face-to-face review for ‘on treatment’ oncology clinics

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Mayuran Sivanandan1,Catherine Sharma1,Pippa Bullard1,Judith Christian1
1Nottingham University Hospitals NHS Trust

Survival and ‘Cure’ of Acute Myeloid Leukaemia (AML) in Children, Adolescents and Young Adults in England

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Mae-Yen Tan1,Aimilia Exarchakou2,Sara Benitez Majano2
1University of Glasgow,2London School of Hygiene & Tropical Medicine

PLGA-Disulfiram microparticles inhibit NF-κB and PD-L1 pathway and reverse chemoresistance induced by mesothelioma stem cells.

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Garima Tyagi1
1Wolverhampton university

Expression Levels of hsa-miR-590-3p in Hepatocellular Carcinoma and Osteosarcoma Cell Lines and its Downstream Target Genes

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Mennatallah Elfar1,Asma Amleh2
1Generations Labs,2The American University in Cairo

The risk of ischemic cerebrovascular disease in head and neck cancer patients after radiotherapy

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Suzy Kim1,Jin Yong Lee1,Young Ae Kim2,Young Ho Jung3
1SMG-SNU Boramae Medical Center, Seoul,23National Cancer Control Institute, National Cancer Center, Goyang,3Seoul National University Bundang Hospital, Seongnam

Investigating the importance of BCL-3/β-catenin signalling in colorectal tumorigenesis

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Penny Timms1,Danny Legge1,Tracey Collard1,Adam Chambers1,Ann Williams1
1University of Bristol

The Roles of Gelsolin in the Regulation of Wnt Signaling in Colorectal Cancer

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Mei Shan Ong1,Shuo Deng1,Tuan Zea Tan2,Shing Chuan Hooi1,Alan Prem Kumar3,Celestial T. Yap1
1National University of Singapore,2Cancer Science Institute,3National University of Singapore, Cancer Science Institute

The continual reassessment method for phase I clinical trial design: is it always more efficient than the 3+3?

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Samantha Hinsley1
1Clinical Trials Unit, Cancer Research UK, Glasgow, UK

Outcomes in patients age 70 and above treated with radical radiotherapy for Head & Neck Cancer

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Saurabh Borgaonkar1,Lisa Hay1,Claire Paterson1,Derek Grose1,Carolynn Lamb1,Stephano Schipani1,Christina Wilson1,Allan James1,Maureen Thomson1
1Beatson

GYS1 inhibition and synthetic lethality with mitochondrial inhibitors in breast cancer

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Ellen de Heer1,Christos E Zois1,Syed Haider2,Daniel Ebner1,Andrew Ratcliffe3,Adrian Harris1
1University of Oxford, Oxford, UK,2Institute of Cancer Research, London, UK,3Novintum Bioscience, London, UK

Metabolic syndrome and renal cell cancer risk in Chinese males: a population-based prospective study.

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Xin Li1,Gang Wang2,Xiaoshuang Feng1,Zhangyan Lyu1,Luopei Wei1,Yan Wen1,Shuohua Chen3,Shouling Wu3,Hongda Chen1,Ni Li1,Min Dai1,Jie He1
1National Cancer Center/ National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College,2Kailuan General Hospital,3Health Department of Kailuan (Group)

MDM2 antagonists synergize with Trametinib in well-differentiated/dedifferentiated liposarcomas.

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Shomereeta Roy1,Audrey Laroche1,Stephanie Verbeke1 Verbeke1,Antoine Italiano1
1INSTITUTE OF BERGONIE, BORDEAUX

Cancer Survivorship; Research is a long term commitment. Does current trial banding reflect this?

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Nicola Rivington1,Ann O'Callaghan1
1Portsmouth Hospitals Trust

Evaluating the impact of patient and public involvement (PPI) in the Life After Prostate Cancer Diagnosis (LAPCD) study

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Jo Brett1,Hugh Butcher2,John Keenan3,Darryl Catton2,Zoe Davey1,Fiona Matley1,Eila Watson1,Penny Wright4,Adam Glaser4,Anna Gavin5
1Oxford Brookes University,2Patient Representative,3Patietn Representative,4University of Leeds,5Queens University Belfast

Retrospective analysis of the prevalence of family history of psoriasis in patients who develop rheumatological immune-related adverse events (irAEs)

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Ionut-Gabriel Funingana1,Christine Parkinson1,Sarah Welsh1,Deniz Tafrali2,Pippa Corrie1,Anshuman Malaviya1
1Cambridge University Hospitals NHS Foundation Trust,2Medical University of Graz

Role of RTK/MAPK/ERK signaling in TGF-β and Activin mediated actions

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Srishti Gautam1
1Indian Institute of Science

Development of a proteomics-based predictor for targeted use of IAP antagonists in colorectal cancer

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Christopher McCann1
1Queen's University Belfast

Novel inherited mutations in genes that associated with breast cancer in Saudi population

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Yousef M Hawsawi1,Edward Cupler21,Abdelrazak Meliti1,Hosam Alardati1
1King Faisal Specialist Hospital and Research Centre-Jeddah

Sulforaphane induces pyroptotic cell death via caspase signaling pathway in Hepatocellular Carcinoma (HCC): an alternative immuno-therapeutic approach

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Kanipandian Nagarajan1,Deyu Li2,Dongxiao Li3
1Henan Provincial People’s Hospital/Henan University, Zhengzhou, China,2Henan Provincial People's Hospital, Zhengzhou, China,3Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

“I felt that I had some people who cared about me.” The impact of real-time remote patient monitoring on clinical practice: experiences of patients and clinicians participating in the eSMART study

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Lisa McCann1,Liane Lewis1,Olubukola Oduntan1,Morven Miller1,Grigorios Kotronoulas2,Eileen Furlong3,Patricia Fox3,Andrew Darley3,Alison Buick3,Aidrian Flowerday4,Emma Ream5,Jo Armes5,Elizabeth Patiraki6,Stylianos Katsaragakis6,Alexander Gaiger7,Geir Berg8,Paul McCrone9,Christine Miaskowski10,Peter Donnan11,Roma Maguire1
1University of Strathclyde,2University of Glasgow,3University College Dublin,4Docobo,5University of Surrey,6University of Athens,7Medical University Vienna,8Sykehuset-Innlandet Hospital Trust,9King's College London,10University of california,11University of Dundee

Novel indoline derivatives induce cell death and cell cycle arrest via the deregulation of oncogenic target genes

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Kumar Subramanian1,Jeyalakshmi Kandhavelu1,Aliyu Musa2,Hande Yapislar3,Meenakshisundaram Kandhavelu2,Paul Ruff1,Clement Penny1
1University of the Witwatersrand,2BioMediTech, Tampere University and Tays Cancer Center,3Acibadem University

Overcoming sorafenib resistance in hepatocellular carcinoma by fasting

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Jelena Krstic1,Isabel Reinisch1,Maria Depaoli1,Natascha Berger2,Christoph Noessing3,Markus Galhuber1,Ines Anders4,Martina Auer1,Elisabeth Moyschewitz1,Beate Rinner5,Martin Pichler6,Roland Malli1,Andreas Prokesch1
1Medical University of Graz, Graz, Austria, Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Graz, Austria,2Department of Obstretics and Gynaecology, Medical University of Graz, Graz, Austria,3Cancer Research UK Beatson Institute, London, UK,4Medical University of Graz, Graz, Austria, Core Facility Alternative Biomodels and Preclinical Imaging, Graz, Austria,5Division of Biomedical Research, Medical University of Graz, Graz, Austria,6Division of Oncology, Medical University of Graz, Graz, Austria

Modulation of tumor microenvironment by targeting cancer associated fibroblasts in dendritic cell based immunotherapy

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Sheefa Mirza1,Clement Penny1,Nayan Jain2,Rakesh Rawal2
1University of Witwatersrand,2Gujarat University

Integrating Germline and Somatic Genetic Test Result Data into the English National Cancer Registration and Analysis Service

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Fiona McRonald1,Brian Shand1,Sophia Richardson1,Katrina Lavelle1,Sally Vernon1,Caroline Brook1,Francesco Santaniello1,Joanna Pethick1,Margreet Luchtenborg1,Steven Hardy1,Jem Rashbass1
1National Disease Registration, Public Health England, London, UK

Dietary changes and nutritional support after a pelvic cancer diagnosis: a cross-sectional study.

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Georgios Saltaouras1,Helen Lightowler2,Shelly Coe2,Amanda Horne3,Sara Matthews3,Loryn Caulfield3,Eila Watson4
1Oxford Institute of Nursing, Midwifery and Allied Health Research, Oxford Brookes University,2Department of Sport, Health Sciences and Social Work, Oxford Brookes University, Oxford, UK,3Department of Oncology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK,4Oxford Institute of Nursing, Midwifery and Allied Health Research, Oxford Brookes University, Oxford, UK

Mapping Cellular Subpopulations within Triple Negative Breast Tumors Provides a Tool for Cancer Sensitization to Radiotherapy

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Ariel M. Rubinstein1,Heba Alkhatib1,Swetha Vasudevan1,Shira Stefansky1,Tamar Peretz-Yablonsky2,Avital Granit2,Amichai Meirovich2,Nataly Kravchenko-Balasha1
1Hebrew University of Jerusalem,2Hadassah Medical Center

Treatment and survival in non-metastatic muscle invasive bladder cancer: analysis of a national patient cohort.

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Joseph John1,Mohini Varughese2,Nicola Cooper3,Kwok Wong3,Luke Hounsome3,Sarah Treece4,Susan Harden5
1Taunton and Somerset NHS Foundation Trust, Taunton, UK,2Taunton and Somerset NHS Foundation Trust,3National Cancer Registration and Analysis Service, Public Health England,4North West Anglia NHS Foundation Trust,5Cambridge University Hospitals NHS Foundation Trust

Acupuncture for the treatment of paraneoplastic night sweats.

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Visweswaran Ramasamy1
1John Taylor hospice

Assessment of the role of the preoperative neutrophil-lymphocyte ratio as a prognostic biomarker in nonmetastatic rectal cancer

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Manar Almusarhed1,Osamah Al-Asadi1,Azhar Rizvi1,Anil Hermanad1,Qamar Zaman1,Somnath Mukherjee1,Hany Eldeeb1
1Milton Keynes Universiy Hospital

Elevated Parkinson’s-like tumour signalling from very early-stage colorectal cancer is associated with disease relapse

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Aoife McCooey1,Keara Redmond1,Emma Kerr1,Daniel Longley1,Philip Dunne1,S-cort Consortium2
1Queen's University Belfast,2S:CORT Consortium

Biweekly cetuximab in combination with capecitabine and oxaliplatin (XELOX) or irinotecan (XELIRI) in patients with metastatic colorectal cancer

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Jamal Zekri1,Ehab Mosaad2,Refaei Belal Ibrahim3,Kamel Mohamed Kamal4,Adnan Hussain5,Mohammed Abbas Baghdadi6
1College of Medicine, Al-Faisal University, King Faisal Specialist Hospital (Jeddah),2Medical oncology department, National Cancer Institute, Cairo University,3Department of clinical oncology and nuclear medicine. Faculty of medicine Al Azhar University,4Cairo University,5King Faisal Specialist Hospital and Research Center- Jeddah,6Research Centre, King Faisal Specialist Hospital & Research Centre, Jeddah

Explaining socio-economic differences in bladder cancer survival

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Beth Russell1,Mieke Van Hemelrijck1,Truls Gårdmark2,Lars Holmberg1,Pardeep Kumar3,Andrea Bellavia4,Christel Häggström5
1King's College London, London, UK,2Karolinska Institute, Stockholm, Sweden,3Royal Marsden NHS Foundation Trust, London, UK,4Havard T.H Chan School of Public Health, Boston, US,5Uppsala University, Uppsala, Sweden

Adolescent cancer risk exposures predict intermediate cancer risk exposures at age 24 years: A longitudinal analysis using ALSPAC data

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Caroline Wright1,Richard Martin1,Rona Campbell1,Ruth Kipping1,Matthew Hickman1,Jon Heron1
1University of Bristol

Lung cancer survival in seven high-income countries 2010-2014: assessing the impact of stage at diagnosis by sex (the ICBP SURVMARK-2 project)

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Marzieh Araghi1,Miranda Fidler-Benaoudia2,Melina Arnold3,Eileen Morgan3,Mark Rutherford4,Freddie Bray3,Isabelle Soerjomataram3
1University College London,2Cancer Control Alberta,3International Agency for Research on Cancer (IARC/WHO),4University of Leicester

Identification of novel HNF1B mRNA splicing variants and their qualitative and semi-quantitative profile in selected healthy and tumor tissues

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Jan Hojny1,Nikola Hajkova1,Michaela Bartu1,Pavel Dundr1,Ivana Ticha1
1Institute of Pathology, First Faculty of Medicine, Charles University and General University Hospital in Prague

Pilot randomised trial of online self-monitoring of symptoms during pelvic radiotherapy eRAPID approach (electronic patient self-Reporting of Adverse-events: Patient Information and aDvice)

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Galina Velikova1,Patricia Holch2,Kate Absolom1,Katrina Walker1,Rose Peacock1,Simon Pini1,Susan Davidson3,Jacki Routledge3,Ann M Henry1,Kevin Franks1,Claire Hulme1,Carolyn Morris4,Lucy McParland1,Julia Brown1
1University of Leeds,2Leeds Beckett University,3The Christie Hospital Manchester,4NCRI Consumer Forum

Comprehensive evaluation of mutation spectra detected in primary cutaneous melanomas including the identification of novel loss-of-function mutants

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Nikola Hájková1
1Institute of Pathology, First Faculty of Medicine, Charles University and General University Hospital in Prague

Factor XIIIA variants ³⁴Leu and ⁶⁵⁰Ile demonstrate functional differences for ECM proteins

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Elmena Elfaki1,Aruna Asipu1,Timothy J. Perren2,Alexander F. Markham1,Rashida Anwar1
1University of Leeds,2University of Leeds / Leeds Teaching Hospitals Trust

EXACT: A multicomponent, feasibility, exercise trial for men with metastatic castrate-resistant prostate cancer.

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Gillian Prue1,Malcolm Brown1,Marie Murphy2,Helen McAneney1,Joe O'Sullivan1,Suneil Jain1
1Queen's University Belfast,2Ulster University

High plasmatic IL-8 and low nitrites levels are independent predictors of poor prognosis in nasopharyngeal carcinoma patients

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Ahmed Amine Zergoun1,Taha Merghoub2,Chafia Touil-Boukoffa3,Mehdi Bourouba3
1University of M'hamed Bougara, Boumerdes,2MSKCC,3USTHB

Barriers and opportunities to cancer research in Wales: health professionals’ perspective

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Ishrat Islam1,Eleanor Webber2,Rachel Savery2,Annmarie Nelson1,Ian Lewis1,Anthony Byrne1
1Cardiff University,2Wales Cancer Research Centre

Smoking status before and after colorectal cancer diagnosis and mortality in Korean men

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Doeun Jang1,Sunho Choe1,Ji Won Park1,Seung-Yong Jeong1,Aesun Shin1
1Seoul National University College of Medicine

Estimating the gap in the provision of specialist cancer nurses in England

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Rachel White1,Jacqueline Goodchild1
1Macmillan Cancer Support

Friendship in the stable phase of cancer

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Hilde Buiting1,Michelle van Eijk2,Daniel de Vries3
1Netherlands Cancer Institute,2University of Amsterdam / Netherlands Cancer Institute,3university of Amsterdam

Microgel Matrices for Human Cancer Organoid Production

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Jessica Pinheiro de Lucena-Thomas1,Kim Luetchford2,Marianne Ellis2,Paul De Bank1
1University of Bath,2Cellesce Ltd

Inhibition of prostate cancer cell growth, motility and ability to alter monocyte/macrophage lineage commitment by a novel TRAF6 inhibitor

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Denise Giovana Carrasco Gonzalez1,Ryan T. Bishop2,Antonio Maurizi3,Silvia Marino4,Anna Sparatore5,Mattia Capulli3,Aymen I. Idris1
1University of Sheffield,2Moffitt Cancer Centre,3University of L’Aquila,4Indiana University,5University of Milano

Serum hormones and prostate cancer incidence and mortality in UK Biobank

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Ruth Travis1,Eleanor Watts1,Georgina Fensom1,Aurora Perez-Cornago1,Anika Knuppel1,Naomi Allen1,Marc Gunter2,Richard Martin3,Karl Smith Byrne2,Neil Murphy2,Kostas Tsilidis4,Tim Key1
1University of Oxford,2International Agency for Research on Cancer,3University of Bristol,4University of Ioannina

The landscape of hepatocellular carcinoma in the UK in the past 20 years: the HCCUK/NCRAS partnership.

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Anya Burton1,Robert Driver2,Vinay Kumar3,Katherine Cullen4,Rhys Pockett4,Deborah Fitzsimmons4,Graeme Alexander5,Tim Cross6,Ian Rowe7,Aileen Marshall8
1Public Health England, London, UK,2University of Leeds, Leeds, UK,3University of Liverpool, Liverpool, UK,4Swansea Centre for Health Economics, Swansea, UK,5University College London, London, UK,6Royal Liverpool and Broadgreen Hospitals, Liverpool, UK,7St James University Hospital Leeds, Leeds, UK,8Royal Free Hospital, London, UK