6719 abstracts found.



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Isolation of an epigenetically defined cisplatin tolerant proliferative population from a chemosensitive ovarian cancer cell line

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Alun Passey1,Bob Brown1
1Imperial College London

Enhancement of apoptosis induction effect of docetaxel by suppressing FABP5 activity in prostate cancer cells

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Jiacheng Zhang1,Youqiang Ke1
1University of Liverpool

Outcomes and Prognostic Markers of Patients Admitted to Intensive Care: A Six-Year Analysis

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Kenrick Ng1,Sophie Joury1,Roopinder Gillmore1
1Royal Free Hospital, UK

Defining transcription stress and the effect it has on genome stability

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Diana Zatreanu1,Jesper Svejstrup1
1The Francis Crick Institute

Genetic dependency profiling of synovial sarcoma cell lines

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Samuel Jones1
1Institute of Cancer Research

Changes to the nuclear periphery in disease states

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Ashwini Arvind1
1Faculty of Medicine, Imperial College

A fingerprint of the metastatic niche

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Luigi Ombrato1,Ilaria Malanchi1
1The Francis Crick Institute

Increased vascular permeability contributes to disease progression and drug response in acute myeloid leukemia

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Diana Passaro1,Ander Abarrategi1,Alessandro Di Tullio2,Kevin Rouault-Pierre2,Katie Foster2,Francois Lassailly2,Dominique Bonnet1
1The Francis Crick Institute,2The Francis Crick

A Module-based Regulatory Program Analysis Identifies Association Between EXO1 and MAP Kinase Inactivation in Triple Negative Breast Cancers

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Jelmar Quist1,Hasan Mirza2,Maggie C Cheang3,Melinda Telli4,Andrew N J Tutt2,Anita Grigoriadis5
1Cancer Bioinformatics, Guy’s Hospital, King’s College London, UK,2Breast Cancer Now Research Unit, Guy’s Hospital, King’s College London, UK,3Clinical Trials and Statistics Unit (ICR-CTSU), The Institute of Cancer Research, Surrey, UK,4Department of Medicine, Stanford University School of Medicine, Stanford, California,5Cancer Bioinformatics, Guy’s Hospital, King’s College London, London, UK

Pilot study on GPs’ preference about out patient consultation letters on breast cancer patients.

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Charles Zammit1,Charles Zammit2
1Zammit C Consultancy Limited,2Zammit Consultancy

Reasons why patients accept or decline clinical trials within the gastrointestinal team

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Cyper Allan1,Sarah Brown1
1University of Sheffield

The experience of blood cancer patients on a period of Watch and Wait

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Lauren Dias1,Matt Kaiser1
1Bloodwise

Creation of a peer Mentorship scheme in the POPS trial

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Sophie Alexander1,Linda Wedlake2,Min Cheung3,Julia Murray4,Helen McNair1,David Dearnaley4
1The Royal Marsden NHS Foundation Trust,2NIHR BRC RM Clinical Trials Unit, Royal Marsden NHS Foundation Trust,3NIHR Biomedical Research Centre at The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, London.,4The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, London.

Aspirin Utilization, Compliance and Prevention Of Colorectal Cancer – A Single Centre Perspective.

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Gurpreet Singh Ranger1,Cindy Mckinley-Brown2
1Upper River Valley Hospital, Dalhousie and Memorial Universities,2Upper River Valley Hospital

Mobilising public support to improve development of, access to and kinder drugs for children with cancer – a grass root NGO/Parent led movement

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Angela Polanco1
1Bethany's wish

National regimen-specific consent forms for systemic anti-cancer therapy (SACT)

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Rena Chauhan1,Janine Mansi1,Dulcie Ireland2
1Guy's and St. Thomas' NHS Foundation Trust,2Cancer Research UK

Cancer experiences in people with an intellectual disability: A PhD thesis

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Samantha Flynn1,Nick Hulbert-Williams1,Lee Hulbert-Williams1,Ros Bramwell2
1Chester Research Unit for the Psychology of Health,2University of Chester

How can the EQUATOR Oncology Project help to improve the reporting of randomised controlled trials in oncology?

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Angela MacCarthy1,Shona Kirtley1,Doug Altman1
1University of Oxford

Weight gain in patients receiving adjuvant first line treatment for ovarian cancer

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Jessica Hale1,Tony Fordham2,Rosemary Lord1
1Clatterbridge Cancer Centre,2Liverpool Medical School

An Analysis Of Patient Participation In A Breast Radiotherapy Clinical Trial

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Nicola Rivington1
1Portsmouth Hospitals Trust

Assessing patient preferences and perspectives of precision cancer medicine: A systematic review.

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Ben Fulton1,Robert Jones1,James Paul1
1Glasgow CRUK Clinical Trials Unit

Outcome of Patients with Solid Tumours Admitted to Intensive Care

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Sarah Stewart1,Miriam Hopwood1,Rowan Miller1,Pericao Ana1,Kai-Keen Shiu1,David Walker1,Laura Sellers2
1University College Hospital,2University College `Hospital

What is the evidence for holistic cancer rehabilitation programmes?

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Laura Vail1,Joanne Fisher1,Andrea Marshall1,Gill Furze2,Morna Woods1,Annie Young1
1The University of Warwick,2Coventry University

The impact of tyrosine kinase inhibitors on the treatment of gastrointestinal stromal tumours (GISTs): The Velindre Cancer Centre experience

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Thomas Ashdown1,Carys Morgan2
1Cardiff University School of Medicine,2Velindre Cancer centre

Smoking After Cancer: A Qualitative Study Of The Challenges In Quitting Smoking After A Diagnosis Of, And Treatment For, Head And Neck Cancer

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Ameera Abdelrahim1,Claire Balmer1,Hisham Mehanna2,June Jones2,Janet Dunn1
1Warwick Clinical Trails Unit,2InHANSE

Quality of life outcomes in children and adolescents previously treated for medulloblastoma

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Joanna Stone1,Lynley Marshall1
1Royal Marsden NHS Trust

Managed local follow-up of long term lymphoma survivors – the ADAPT programme

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John Radford1,Valerie Goode2,Ellie White2,Rachel Monkhouse2,Richard Cowan3
1The University of Manchester and the Christie NHS Foundation Trust,2The Christie NHS Foundation Trust, Manchester,3The University of Manchester and the Christie NHS Foundation Trust, Manchester

Endoscopic management of gastrointestinal bleeding in cancer patients with severe thrombocytopenia

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Paul Hampel1,Guilherme Piovezani Ramos2,Moritz Binder2,Manuel Braga Neto2,Dharma Sunjaya2,Badr Al Bawardy2,Elizabeth Rajan2
1Mayo School of Graduate Medical Education,2Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA

Cetuximab related hypersensitivity reactions – worthy of the hype?

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Martin Forster1,Sanjena Mithra2,Tom Marler-Hausen2,Andrew Rogerson2,John Bridgewater3
1UCL / UCLH,2UCLH,3UCL

The implementation of focused performance benchmarking as a method of regional quality improvement in breast cancer care.

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Elizabeth Appleton1,Naik Jay2
1Leeds teaching hospitals,2Mid Yorks NHS Trust

Systemic Anti-Cancer Treatment for Solid Tumours: Why Door-To-Needle Time Is Important For Neutropenic Sepsis

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Hiu Kwan Carolyn Tang1,Doreen Yin Hui Lee2,Helen Mcmilan2,Louise Tweedie2,Karen Lewis2,Chris Jenkins2,Jane Hart2,Doug Hymers2,Sarah Hine2,Hilary Williams3
1Cardiff and Vale University health board,2Royal Gwent Hospital,3Velindre Cancer Centre

Girls’ knowledge about HPV vaccine and cervical cancer

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Corina Chivu1,Aileen Clarke1,Gillian Hundt1
1University of Warwick

How a collaboration between an Academic Maths Department and a local NHS Breast Cancer Service improve patient pathways.

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Pauline Leonard1,Christina Saville1,Honora Smith1,Katarzyna Bijak1,Azmina Verjee2,Navid Izady3
1University of Southampton,2Whittington Hospital,3CASS Business School

Evolution of a Breast Cancer Trials Team

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Murray Brunt1,Marion Evans1,Julie Storer1,Angela Ward1,Rowena Smith1,Alison Myatt1
1University Hospitals of North Midlands

Development of drug-resistant colorectal cancer cell lines to investigate mechanisms of resistance and identify predictive biomarkers of drug response.

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Mario Ortega1,Steven Shnyder1,Steve Shynyder1,Christopher Sutton1,Sadr Shaheed1
1Institute of Cancer Therapeutics (University of Bradford)

Impact Of A CUP Service At The Royal Derby Hospital- One Year On

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Suravi Chatterjee-Woolman1,Jessica Loveless1,Rebecca Warren2,Alison Raworth2,Catherine Shankland2
1University of Nottingham,2Royal Derby Hospital

A retrospective evaluation of the current pathways of assessment and management of patients with neutropenic sepsis at the Northumbria Specialist Emergency Care Hospital

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Caroline Dobeson1,Sobia Sharif2

1Northumbria Healthcare NHS Foundation Trust,2Northern Deanery (Northumbria Healthcare NHS Trust)


Diagnostic pathways for older people with suspected cancer: review of the Addenbrooke’s hospital rapid access geriatric assessment service (RADAR)

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Francesca Holt1,Mary Denholm1,Joanna Hampton1,Pippa Corrie1
1Cambridge University Hospital NHS Foundation Trust

Multidisciplinary Meetings: should all patients be discussed?

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Sadaf Jafferbhoy1,Ammara Hasan1,Robert Kirby1,Sankaran Narayanan1,Soni Soumian1
1University Hospital of North Midlands

General Practitioners’ views on the provision of oral anti-cancer medicines

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Farida Butt1
1Kingston University

Breast One-stop Clinic: Concordance between Primary and Secondary Care

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Sadaf Jafferbhoy1,Sarah Yuzari2,Robert Kirby2,Soni Soumian2
1University Hospital of North Midlands,2University Hospital of North Staffordshire

First impressions count: Initial clinical and radiological features independently predict for overall survival in older patients with Glioblastoma

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Cressida Lorimer1,Catherine Hanna2,Anthony Chalmers2,Frank Saran3,Juliet Brock4
1Brighton and Sussex Medical School,2Beatson West of Scotland Cancer Centre,3The Royal Marsden Hospital,4Sussex Cancer Centre

Dose escalation of axitinib on disease progression as a strategy in the treatment of metastatic renal cell carcinoma

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Gary Doherty1,Deirdre Lynskey2,Athena Matakidou2,Kate Fife2,Tim Eisen2
1University of Cambridge,2Cambridge University Hospitals NHS Foundation Trust

Treatment with neoadjuvant BRAF/MEK inhibitors yields high response rates in patients with high-risk resectable melanoma

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Jennifer Wargo1,Courtney Hudgens1,Michael Tetzlaff1,Rodabe Amaria1,Alex Reuben1,Peter Prieto1,Elizabeth Burton1,Vancheswaran Gopalakrishnan1,Hong Jiang1,Christine Spencer1
1The University of Texas MD Anderson Cancer Center

Chk1 inhibition activates replication stress and catastrophe in an unperturbed S-phase

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Andrew Massey1,Joanne Wayne1,Teresa Brooks1
1Vernalis Research

MicroRNA regulation of DNA damage response to radiotherapy

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Nina Raulf1,Yae-Eun Suh1,Eleanor Fewings1,Joop Gaeken1,Katherine Lawler1,Mahvash Tavassoli1
1King's College London

Co-delivery of Doxorubicin and Radionuclide therapy using EGF-tagged drug carriers for the treatment of EGFR-positive cancer cells

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Jyothi Menon1,Joshua Owen1,Robert Carlisle1,Katherine Vallis1
1University of Oxford

Role of miR-9 and its target CXCR4 in head and neck cancers

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Hersi Mohamed Hersi1,Nina Raulf1,Katherine Lawler1,Joop Gaken1,Mahvash Tavassoli1
1King's College London

Targeting KRAS dependent tumors with AZD4785, a high-affinity therapeutic antisense oligonucleotide inhibitor of KRAS

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Sarah Ross1,Alexey Revenko2,Lyndsey Hanson3,Rebecca Ellston3,Anna Staniszewska3,Nicola Whalley3,Sanjay Pandey4,Mitchell Revill3,Claire Rooney3,Linda Buckett3,Stephanie Klein3,Kevin Hudson3,Michael Zinda3,David Blakey3,Brett Monia2,Lyne Paul3,Robert Macleod2
1AstraZeneca,,2Ionis Pharmaceuticals,3AstraZeneca,4Ionis

AR targeted therapy in ovarian cancer: first results with abiraterone in the phase II Cancer of the Ovary Abiraterone (CORAL) Trial (CRUKE/12/052)

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Susana Banerjee1,Lucy S Kilburn2,Rebecca Bowen3,Holly Tovey2,Marcia Hall4,Stan Kaye1,Gordon Rustin4,Martin Gore1,Jennifer McLachlan1,Ayoma Attygalle1,Nina Tunariu1,Joao Paulo Lima1,Peter Chatfield2,Sue Martin2,Elizabeth Folkerd2,Margaret Hills1,Sophie Perry2,Gerhardt Attard2,Mitch Dowsett1,Judith M Bliss2
1Royal Marsden NHS Foundation Trust,2The Institute of Cancer Research,3Royal United Hospitals Bath NHS Foundation Trust,4Mount Vernon Cancer Centre