6719 abstracts found.



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Identification of Texture Features from FDG PET images that are associated with Survival Outcomes in Non-small Cell Lung Cancer

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Mubarik Arshad1,Andrew Thornton2,Nicola Rodgers2,Andrew Scarsbrook3,Garry McDermott3,Gary Cook4,Sue Chua5,Richard O’Connor6,Tara Barwick7,Andrea Rockall7,Eric Aboagye7
1Imperial College London and Imperial College Healthcare NHS Trust,2Imperial College London Cancer Imaging Centre and Department of Nuclear Medicine,3Department of Nuclear Medicine, Level 1, Bexley Wing, St James’s University Hospital, Beckett Street, Leeds, LS9 7TF,4St. Thomas’ Hospital Department of Nuclear Medicine, Westminster Bridge Rd, London SE1 7EH.,5The Royal Marsden Hospital Department of Nuclear Medicine, Downs Rd, Sutton SM2 5PT,6Nottingham University Hospital Department of Nuclear Medicine, Queen's Medical Centre, Derby Rd, Nottingham NG7 2UH.,7Imperial College London Cancer Imaging Centre and Department of Nuclear Medicine, Hammersmith Hospital, Du Cane Road, London W12 0HS

Mass-spectrometry profiling of extracellular matrix identifies citrulline as marker of colorectal cancer liver metastasis

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Arseniy Yuzhalin1,Su Yin Lim2,Alex Gordon-Weeks2,Rebecca Konietzny3,Benedikt Kessler3,Ruth Muschel2
1,2Cancer Research UK/MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK,3TDI Mass Spectrometry Laboratory, Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK

Fingerprinting Heterogeneity of Glioma using PET-MR Information

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Fatemeh Nejat1
1Klinikum Grosshadern

A retrospective study of the toxicities of immunotherapies used in the treatment of disseminated malignant melanoma and an audit of their management

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Jonathan Heseltine1,Rosemary Lord1,Joe Sacco1,Ernie Marshall1,Joanne Upton1,Anna Olsson-Brown1
1Clatterbridge Cancer Centre

Liquid Biopsy in Metastatic Prostate Cancer

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Jenny Antonello1,Jakub Chudziak1,Shambhavi Srivastava1,Adnan Syed1,Deborah Burt1,Mahmood Ayub1,Alan Redfern1,Bedirhan Kilerci1,Esther Baena1,Dominic Rothwell1,Noel Clarke2,Caroline Dive2,Ged Brady2
1CRUK,2cruk

Programmed death-ligand 1 (PDL-1) and immune infiltrates are prognostic for better outcome and enriched in the ATM (ataxia telangiectasia mutated)-low segment of gastric cancer (GC)

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Elaine Kilgour1,Helen K. Angell2,Kyoung-Mee Kim3,Soomin Ahn3,Seung Tae Kim3,Alan Sharpe2,Julia Ogden2,Anna Davenport4,J. Carl Barrett5,Darren Hodgson6,Jeeyun Lee3
1AstraZeneca,2AstraZeneca, Cambridge UK,3Samsung Medical Center, Sungyunkwan University Korea,4University Hospital South Manchester UK,5AstraZeneca, Boston USA,6AstraZeneca, Macclesfield UK

Accelerative integromics: dynamic biomarker discovery using big data.

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Seedevi Senevirathne1,Darragh McArt2,Philip Dunne2,Gerald Li2,Peter Hamilton2,Suneil Suneil2,Manuel Salto-Tellez2,Simon McDade2
1Center for Cancer Research and Cell Biology, Queens University Belfast,2Centre for Cancer Research and Cell Biology, Queen's University Belfast

Delineating the role of chromosome 6 aberrations associated with the prognosis of primary uveal melanoma.

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Nawal Alshammari1,David Hammond1,Karen Sisley1
1University of Sheffield

Expression of Soluble c-Met in the serum and peritoneal fluid of the patients with different stages of Endometrial Cancer

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Farhad Mashayekhi1,Zivar Salehi1,Ebrahim Mirzajani2
1University of Guilan, Rasht, Iran,2Cellular and Molecular Research Center, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran.

Soluble CD44 in the serum and peritoneal fluid of the patients with Endometrial Cancer

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Zivar Salehi1,Sohail Mashayekhi2,Ebrahim Mirzajani3
1University of Guilan,2Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran.,3Cellular and Molecular Research Center, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran.

HER2 testing in gastric adenocarcinoma

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Owen Cain1,Owen Cain1,Claire Swift1,Tina Mullis1,Frances Hughes1,Matthew Smith1,Brendan O'Sullivan1,Philippe Taniere1
1Queen Elizabeth Hospital Birmingham

Hypofractionated dose painting IMRT for intermediate to high risk localised prostate cancer: boosting to 68 Gy in 20 fractions

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Joachim Chan1,Thelma Rowntree1,Laura Howard1,John NH Brunt1,Isabel Syndikus1
1Clatterbridge Cancer Centre NHS Foundation Trust

A systematic review and meta-analysis on the role of music in reducing anxiety and discomfort during flexible sigmoidoscopy

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Arun P Shanmuganandan1,Muhammed Siddiqui1,Nicholas Farkas1,Rhys Thomas1,Said Mohamed1,Al Mutaz Abulafi1,Robert Swift1
1Croydon University Hospital NHS Trust

The impact of ApE1 gene polymorphism on endometrial cancer in Iranian population

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Farhad Mashayekhi1,Zivar Salehi1,Ebrahim Mirzajani2
1University of Guilan, Rasht, Iran,2Cellular and Molecular Research Center, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran.

Acceleration of Gene Expression Connectivity Mapping using GPUs within the QUADraTic System

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Jessica Black1,Darragh McArt2,Hans Vandierendonck3,Paul O'Reilly2,Eamonn McKernan3,Manuel Salto-Tellez2
1Bioinformatics and Integromics Laboratory, CCRCB,2Centre for Cancer Research and Cell Biology, Queen's University Belfast,3School of Electronics, Electrical Engineering and Computer Science (EEECS), Queen's University Belfast

Can we use N-acetyl-L-aspartyl-L-glutamate peptidase-like 2 to target drugs to cancer cells?

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Hayley Luxton1,Ben Simpson1,Michael Brown2,Jonathan Kay1,Suraj Menon3,Noel Clarke4,Hayley Whitaker1
1University College London,2The University of Manchester,3University of Cambridge,4University of Manchester

Profiling circulating microRNAs in early screen detected breast cancer

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Daniel Fernandez Garcia1,David S. Guttery1,Karen Page1,Allison Hills2,Laura Woodley2,Justin Stebbing2,R. Charles Coombes2,Jacqueline A. Shaw1
1University of Leicester,2Imperial College

Biomarker based identification of aggressive prostate cancer in blood and urine samples

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Lina Maria Carmona Echeverria1,Thomas Johnson2,Matthew Eldridge3,Sarah Vowler3,Anne George2,Marie Corcoran2,Johannah Burge2,Sara Stearn2,David Neal2,Hayley Pye4,Susan Heavey4,Hayley Whitaker4
1University College London,2Uro-oncology Group, Cambridge University,3Bioinformatics Core Facility, CRUK Cambridge Institute,4Division of urgery and Interventional Science, University College London

30-day mortality after systemic anti-cancer treatment for breast and lung cancer in England – which factors affect the risk? – the first national population based study

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Emma Saxon1,Michael Wallington2,Matthew Wickenden1,David Dodwell2,Martine Bomb2,Rebecca Smittenaar3,Sean McPhail2,Jem Rashbass2
1Cancer Research UK,2Public Health England,3Cancer Rsearch UK

Using mp-MRI guided prostate needle biopsy samples to improve prostate cancer diagnosis.

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Jonathan Olivier1,Jonathan Kay1,Alex Freeman1,Hashim Ahmed1,Caroline Moore1,Mark Emberton1,Hayley Whitaker1
1University College London

Evolution of gastro-oesophageal cancers and selection of therapy resistant subclones through metastatic dissemination

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Matthew Davies1
1Institute of Cancer Research

Novel diagnostic and prognostic prostate cancer biomarkers buffer the translational burden of neoplastic transformation

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Jonathan Kay Kay1,Lars Egevad2,Anne Warren3,Amanda Seipel2,Charlie Massie4,Fredrik Wiklund2,Benjamin Thomas5,Steve Hawkins6,Hayley Luxton1,Ian Mills7,Peter Wiklund2,Benjamin Simpson1,Jodi Miller5,Suraj Menon5,Gabrielle Fisher2,Susan Heavy8,Hayley Pye1,Jack Cuzick9,David Neal10,Hayley Whitaker1
1University college london,2Karolinska Institute,3Cambridge University,4University of Cambridge,5CRUK cambridge,6CRUK,7Centre for Molecular Medicine Norway,8university college london,9CRUK Queen Mary University of London,10Oxford university

INNOVATE: A prospective cohort study combining serum and urinary biomarkers with novel diffusion-weighted MR imaging for the prediction and characterisation of prostate cancer.

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Hayley Whitaker1,Hayley Pye2,Lina Carmona2,Susan Heavey2,Alex Freeman2,Manuel Rodriguez-Justo2,Daniel Alexander2,Eleftheria Panagiotaki2,Edward Johnston3,Teresita Beeston3,Hashim Ahmed2,Tony Ng4,Shonit Punwani3
1University College London,2UCL,3UCLH,4CRUK

Expression of PD-L1 in non-small cell lung cancer: a series of 1,107 cases

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Matthew Evans1,Brendan O'Sullivan1,Alison Teague1,Frances Hughes1,Claire Swift1,Matthew Smith1,Daniel Kearns1,Philippe Taniere1
1Queen Elizabeth Hospital Birmingham

Assessing mechanisms of tumour evolution using alignment-free methods

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Aideen Roddy1,Anna Jurek2,Alex Stupnikov3,Paul O'Reilly3,Phillip Dunne3,David Gonzales de Castro3,Kevin Prise3,Manuel Salto-Tellez3,Darragh McArt3
1Queen's University Belfast,2School of Electronics, Electrical Engineering and Computer Science, Queen's University Belfast,3Centre for Cancer Research and Cell Biology, Queens University Belfast

A novel cell surface pancreatic and cholangiocarcinoma biomarker that promotes resistance to Gemcitabine

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Jonathan Kay1,Frances Richards2,Laura Bucklow2,Rebecca Brais3,Aarthi Gopinathan2,Hayley Luxton4,Eva Papachristou2,Clive D'Santos2,Duncan Jodrell2,Hayley Whitaker1
1University College London,2CRUK Cambridge Institute,3Addenbrooke's Hospital,4University College london

Changing referral patterns and colorectal cancer (CRC) detection rates over 10 years in a UK specialist centre.

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Elena Velten1,Angus McNair1
1Gloucestershire NHS Trust

miRNA SIGNATURES AND CONTRIBUTION TO FAMILIAL COLORECTAL CANCER: AN IN SILICO APPROACH

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Omnia Yousif1,Suleiman Suleiman2,Muntaser Ibrahim3
1Institute of Endemic Diseases,2Suba University Hospital,3Department of Molecular Biology, Institute of Endemic Diseases, University of Khartoum

Preclinical Assessment of Response to Cetuximab and Combination Treatment with [18F]ICMT-11 and [18F]FLT PET Imaging

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Kathrin Heinzmann1,Quang-De Nguyen1,Diana Brickute1,Chris Barnes1,Steve Stribbling1,Eric Aboagye1
1Imperial College London

Performance review of TEMS(Transanal Endoscopic MicroSurgery)/TAMIS(TransAnal Minimally Invasive Surgery) for excision of rectal lesions in a District General Hospital

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Arun P Shanmuganandan1,Bernadette Pereira1,Nicholas Farkas1,Muhammed Siddiqui1,Said Mohamed1,Robert Swift1,Al mutaz Abulafi1
1Croydon University Hospital NHS Trust

Long term follow up: what are the implications on Research Delivery Staff?

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Nancy Hopewell1,Teresa Lockett1,Karthik Ramasamy1,Penny Williams2
1CRN: Thames Valley & South Midlands,2CRN: North East North Cumbria

Where next for cancer services in Northern Ireland, Scotland and Wales? An evaluation of priorities to improve patient care

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Emlyn Samuel1,Leo Ewbank1,David Morrison2
1Cancer Research UK,2University of Glasgow

Defining the Surgical Contribution to Cancer Research in the UK

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Richard Shaw1,Shamaila Anwar1,Jonathan Gower1,Nigel Bundred1,Matthew Seymour1
1NIHR Clinical Research Network: Cancer

EGFR mutation testing on cell free circulating tumour DNA: the Birmingham Molecular Pathology Diagnostic Service

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Claire Swift1,Matthew Smith1,Amina Mulla1,Frances Hughes1,Brendan O'Sullivan1,Gary Middleton1,Philippe Taniere1
1Queen Elizabeth Hospital Birmingham

The molecular epidemiology of KRAS and NRAS mutations in 2,761 colorectal adenocarcinomas

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Matthew Evans1,Brendan O'Sullivan1,Frances Hughes1,Claire Swift1,Reena Dessi1,Tina Mullis1,Matthew Smith1,Philippe Taniere1
1Queen Elizabeth Hospital Birmingham

Exploring Clinical Decision Making in the Treatment of Cancer in Older Patients

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Helen Beck1,Emlyn Samuel1,Kerry Allen2
1Cancer Research UK,2University of Birmingham

Optimising oncology outcomes with a mobile app for breast cancer patients: A qualitative evaluation

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Anne Bruinvels1,David Bruinvels1
1Px HealthCare

Audit of BRCA1 and BRCA2 gene mutation detection rate in women with triple negative breast cancer diagnosed under 60 years

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Cecilia Compton1,Rose Sarah1,Izatt Louise1,Ruddy Deborah1,Shaw Adam1,Tripathi Vishakha1,Walsh Cheryl1,Nayanta Sodha1,Anushka Srinivas2,Anju Kulkarni1
1Guy's Hospital,2King's College London Medical School

Defining patient-centred real-life clinical pathways during chemotherapy

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Elaine Dunwoodie1,Karl Baker2,Angelina Kurniati3,Owen Johnson3,Jane Wolstenholme4,Jose Leal4,Christopher Price5,Chris Twelves6,Geoff Hall6
1University of Leeds,2X-lab Ltd,3School of Computing, University of Leeds,4Health Economics Research Centre, University of Oxford,5Nuffield Department of Primary Care Health Sciences, University of Oxford,6Leeds Institute of Cancer & Pathology, University of Leeds

Research Opportunities for Teenage and Young Adult Cancer Patients

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Amos Burke1,Shamaila Anwar1,Jonathan Gower1,Matthew Seymour1
1NIHR Clinical Research Network

Frequency and nature of presenting abdominal symptoms in cancer patients before diagnosis: evidence to inform the design and evaluation of generic symptom awareness campaigns

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Minjoung Monica Koo1,Christian von Wagner1,Gary Abel2,Sean McPhail3,Greg Rubin4,Georgios Lyratzopoulos1
1UCL,2University of Exeter,3NCRAS, Public Health England,4University of Durham

Typical and atypical symptoms in women with breast cancer: Evidence of variation in diagnostic intervals from a national audit of cancer diagnosis

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Minjoung Monica Koo1,Christian von Wagner1,Gary Abel2,Sean McPhail3,Greg Rubin4,Georgios Lyratzopoulos1
1UCL,2University of Exeter,3NCRAS, Public Health England,4University of Durham

A multicentre survey of teenage and young adult cancer patients: fatigue is prevalent, poorly managed and perpetuates long term

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Anna Spathis1,Helen Hatcher1,Sara Booth2,Faith Gibson3,Patrick Stone4,Laura Abbas1,James Brimicombe2,Pia Thiemann2,Martin McCabe5,Rachel Campsey6,Louise Hooker7,Wendy Moss1,Jane Robson1,Stephen Barclay2
1Cambridge University Hospitals NHS Foundation Trust,2University of Cambridge,3Great Ormond Street Hospital,4University College London,5University of Manchester,6Christie NHS Foundation Trust,7University Hospital Southampton NHS Foundation Trust

COAST (Cisplatin Ototoxicity Attenuated by Aspirin Trial): A phase II double blind, randomised controlled trial to establish if aspirin reduces cisplatin induced hearing loss

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Emma King1,Simon Crabb1,Karen Martin1,Julia Abab1,Ian Ratcliffe1,Roger Thornton1,Ben Lineton1,Mary Ellis1,Ron Moody2,Louise Stanton1,Tom Geldart3,Mike Bayne4,Joe Davies5,Carolynn Lamb6,Sanjay Popat7,Christopher Nutting7,John Chester8,Andrew Hartley9,Gareth Thomas1,Christian Ottensmeier1,Robert Huddart10,Keith Pugh11
1University of Southampton,2Patient representative,3Royal Bournemouth Hospital Trust,4Poole Hospital NHS Foundation Trust,5Poole Hospital NHS Foundation Tru,6University of Glasgow,7Royal Marsden Hospital,8University of Cardiff,9University of Birmingham,10Royal marsden hospital,11Southampton Clinical Trials Unit

Quantifying long-term morbidity following cervical cancer treatment: A retrospective comparison of the Royal College of Radiologist’s (RCR) Morbidity Audit and routine population-based cancer datasets

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Katie Spencer1,Amy Downing2,Jane Maher3,Louise Whitehouse2,James Thomas4,Eva Morris2
1University of Leeds/Leeds Teaching Hospitals NHS Trust,2University of Leeds,3Macmillan Cancer Support/Mount Vernon Cancer Centre,4NHS England

A Dietary and Physical Activity Interventions for Colorectal Cancer Survivors: A Randomized Controlled Trial

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Judy Ho1,Daniel Fong2,Chun-fan Lee3,Duncan Macfarlane3,Ester Cerin4,Antoinette Lee5,Leung Sharron6,Wynnie Chan7,Ivy Leung8,Sharon Lam1,Aliki Taylor9,Weijie Gong10,Kar-keung Cheng9
1Department of Surgery, The University of Hong Kong,2School of Nursing, The University of Hong Kong,3School of Public Health, The University of Hong Kong,4Institute of Health and Ageing, Australian Catholic University,5Department of Psychiatry, The University of Hong Kong,6School of Nursing, Hong Kong Baptist Hospital,7School of Professional and Continuing Education, The University of Hong Kong,8Department of Dietetics, Queen Elizabeth Hospital,9Department of Public Health, Epidemiology and Biostatistics, University of Birmingham,10

The current evidence base for the feasibility of 48-hour Continuous Subcutaneous Infusions (CSCIs): a systematically-structured review.

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James Baker1,Andrew Dickman2,Stephen Mason2,John Ellershaw2
1Royal Liverpool and Broadgreen University Hospitals NHS Trust,2Marie Curie Palliative Care Institute Liverpool

Follow up after cancer treatment: Improving access to supported self-management through testing of a GP led Active Inclusion Pathway

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Lucy Johnston1,Dr Sineaid Bradshaw2,Rossi Durie3,Karen Campbell1
1Edinburgh Napier University,2Wester Hailes Health Centre, Wester Hailes Healthy Living Centre,3Westerhaven Macmillan Cancer Information and Support Centre

Decision-making of Treatment in Advanced Lung Cancer; the PACT Study: An Intervention to Support Advanced Lung Cancer Patients and Their Clinicians When Considering Systemic Anti-Cancer Therapy

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Despina Anagnostou1,Catherine Sampson1,Stephanie Sivell1,Simon Noble1,Anthony Byrne1,Annmarie Nelson1
1Cardiff University

Serious Illness Care Programme UK: Assessing the ‘face validity’ and acceptability of the Serious Illness Conversation Guide (SICG) for use within the UK health care setting.

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Tamsin McGlinchey1,Stephen Mason1,Alison Coackley2,Maria Maguire2,Francine Maloney3,Justine Sanders3,Joanna Paladino3,Susan Block3,Peter Kirkbride2,John E Ellershaw1
1Marie Curie Palliative Care Institute Liverpool, University of Liverpool,2Clatterbridge Cancer Centre NHS Foundation Trust,3Ariadne Labs