6719 abstracts found.



Results filter

Using the Virtual Tumour to improve the efficacy of the Gemcitabine – Docetaxel combination treatment through delivery schedule optimisation

Year:

Session type:

Eric Fernandez1, David Orrell1, David Fell1, Christophe Chassagnole1
1Physiomics plc, Oxford, UK

Development of a mathematical model for drug delivery to tumours

Year:

Session type:

Christian Groh1, Matthew Hubbard2, Pam Jones3, Paul Loadman4, Nagarajan Periasamy4, Roger Phillips4, Brian Sleeman1, Stephen Smye5, Christopher Twelves3
1Department of Applied Mathematics, University of Leeds, Leeds, UK, 2School of Computing, University of Leeds, Leeds, UK, 3Leeds Institute of Molecular Medicine, Leeds, UK, 4Institute of Cancer Therapeutics, University of Bradford, Bradford, UK, 5Division of Medical Physics, Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, UK

Identifying novel regulatory relationships between the ovarian cancer candidate genes: EVI1; FOLR1 and SCNN1A

Year:

Session type:

Resha Alrabeh1, Kristy Shipman1, Nona Rama1, Hani Gabra1, Bob Brown1, Euan Stronach1, Roshan Agarwal1
1Imperial College, London, UK

A genome-wide siRNA screen approach to identify novel components of the ATM-ATMIN signalling pathway

Year:

Session type:

Tianyi Zhang1, Joanna Loizou1,2, Axel Behrens1
1London Research Institute, London, UK, 2Research Center for Molecular Medicine, Vienna, Austria

DNA polymerase eta is a predictive biomarker for oxaliplatin chemotherapy in patients with oesophageal cancer

Year:

Session type:

Nils H. Nicolay1, Richard Gillies1, Thomas MacGregor1, Rose Wharton1, Somnath Mukherjee2, Srinivasan Madhusudan2, Patrick G. Johnston3, Mark Middleton1, Thomas Helleday1, Ricky A. Sharma1
1University of Oxford, Oxford, UK, 2Nottingham City Hospital, Nottingham, UK, 3Queen's University Belfast, Belfast, UK

Using metastatic breast cancer cell conditioned media for identification of potential biomarkers for bone metastasis

Year:

Session type:

Jules Westbrook1, Steph Wallbank1, Alexandre Zougman1, David Cairns1, Penelope Ottewell2, Ingunn Holen2, Robert Coleman2, Peter Selby1, Rosamonde Banks1, Janet Brown1,2
1St James's University Hospital, Leeds, UK, 2University of Sheffield, Sheffield, UK

Exploiting the embryonic environment to reprogram neuroblastoma cells

Year:

Session type:

Rachel Carter1, Violaine See1, Mike White1, Heather P McDowell2, Barry L Pizer2, Louis Chesler3, Paul D Losty4, Edwin Jesudason4, Diana J Moss1
1Institute of Translational Medicine, University of Liverpool, Liverpool, UK, 2Alder Hey Children’s NHS Foundation Trust, Alder Hey Children’s Hospital, Liverpool, UK, 3Division of Paediatric Oncology, The Institute of Cancer Research, Sutton, UK, 4Academic Paediatric Surgery, Division of Child Health, Alder Hey Children's NHS Foundation Trust, University of Liverpool, Liverpool, UK

The use of FANCD2 mono-ubiquitination as a predictive marker for mitomycin C and ATM inhibitor sensitivity in cancer cells

Year:

Session type:

Andrew Thomason1, Bhavika Patel1, Pia Thommes1, Alan Lau1
1AstraZeneca R&D, Oncology Innovative Medicines, Alderley Park, Macclesfield, Cheshire, UK

5T4 oncofoetal glycoprotein expression correlates with differential biological responses to CXCL12 through reciprocal expression of CXCR4 or CXCR7

Year:

Session type:

Owen McGinn1, Peter Stern1
1Paterson Institute for Cancer Research, Immunology, Manchester, UK

Development of an in vitro endothelial cell tube formation assay to demonstrate the effects of siRNA and small molecules on disruption of established vessels.

Year:

Session type:

Cath Eberlein1, Hazel Weir1, Darren Cross1
1AstraZeneca, Chesire, UK

Enhanced anti-tumour activity of cisplatin with a novel drug delivery system

Year:

Session type:

Balaji Venugopal1, Nial Wheate2, Jane Plumb1
1Univeristy of Glasgow, Glasgow, UK, 2University of Strathclyde, Glasgow, UK

Mechanisms of DNA replication initiation

Year:

Session type:

Kin Fan On1, John Diffley1
1Clare Hall Laboratories, CR-UK London Research Institute, London, UK

Inhibition of the phosphatidylinositol-3 kinase pathway in melanoma cells in relation to senescence

Year:

Session type:

Milap G Rughani1, Heather M Shaw2, Colin R Goding2, Mark R Middleton1
1University of Oxford, Oxford, UK, 2Ludwig Institute for Cancer Research, Oxford, UK

Quantitative assessment of tumour infiltrating lymphocytes using GenieTM pattern recognition software for the separate analysis of tumour versus stroma in head and neck squamous cell carcinoma (HNSCC) improves biomarker reproducibility

Year:

Session type:

Xiu Huan Yap1, Helen Angell2, Neil Gray1, Christopher Womack1, Robert Wilkinson1, Marie Cumberbatch1
1Innovative Medicines Oncology, Macclesfield, UK, 2University of Nottingham, Nottingham, UK

Expression of interleukin-8, IL-8RA and IL-8RB in ovarian carcinoma and their effect on platinum resistance

Year:

Session type:

Euan Stronach1, Radhika Aiyappa1, Senthuran Jeyapalan1, Tankut Guney1, James Studd1, Hani Gabra1, Mona El-Bahrawy1
1Imperial College London, London, UK

Studies in ovarian cancer follow up

Year:

Session type:

Katie Griggs1, Ahmed Master1, Elis Williams1
1University of Leeds, Leeds, UK, 2Airedale General Hospital, West Yorkshire, UK, 3Bradford Royal Infirmary, Bradford, UK

Improved overall survival due to catumaxomab treatment: Follow-up results from a pivotal phase II/III study

Year:

Session type:

S. Parsons1, M.M. Essing2, C. Schmidt-Rimpler2
1Nottingham University Hospitals NHS Trust, Notingham, UK, 2Fresenius Biotech, Munich, Germany

Electronic patient-reported outcomes from cancer survivors (ePOCS): Preliminary results from feasibility testing of a scalable electronic system for collecting PROs and linking with cancer registry data

Year:

Session type:

Laura Ashley1, Helen Jones1, Galina Velikova1, David Forman2, Owen Johnson1, Alex Newsham1, Ada Keding1, James Thomas3, Penny Wright1
1University of Leeds, Leeds, UK, 2International Agency for Research on Cancer, Lyon, France, 3National Cancer Intelligence Network, Leeds, UK

Quartz: a software platform for the management, visualization and analysis of large scale, multimodal genomic and bioimage data.

Year:

Session type:

Alain Pitiot1, Francois Morvillier1
1Ilixa Limited, Nottingham, UK

The role for primary care in the management and follow-up of patients with lung cancer

Year:

Session type:

Christine Campbell1, Elvis Amoakwa2, Chantelle Anandan1, Gill Highet1, Scott Murray1, Richard Neal2, Peter Rose3, David Weller1
1University of Edinburgh, Edinburgh, UK, 2University of Cardiff, Wrexham, UK, 3University of Oxford, Oxford, UK

Chapped lips and cold sores during cytotoxic chemotherapy, and the perceived effectiveness of self medicated lip salves  

Year:

Session type:

Mea Holm1,3, Robert Thomas1,4, Madeleine Williams1,2
1The Primrose Research Unit, Bedford, UK, 2Cranfield University, Bedford, UK, 3Oxford University, Oxford, UK, 4Addenbrooke's Hospital Cambridge University, Cambridge, UK

Moving on: leaving the ‘security blanket’ of paediatric oncology care.  A qualitative exploration of the experience of transitioning from paediatric to adult cancer care

Year:

Session type:

Lisa McCann1, Yvonne Wengström2, Nora Kearney1
1University of Dundee, Dundee, UK, 2Karolinska Institutet, Huddinge, Stockholm, Sweden

The Mini-Mental Adjustment to Cancer Scale (Mini-MAC):  Re-analysis of its psychometric properties in a sample of 160 mixed cancer patients

Year:

Session type:

Nick Hulbert-Williams1, Lee Hulbert-Williams2, Val Morrison3, Richard Neal4, Clare Wilkinson4
1University of Chester, Chester, UK, 2University of Wolverhampton, Wolverhampton, UK, 3Bangor University, Bangor, UK, 4Cardiff University, North Wales Clinical School, Wrexham, UK

Exercise and dietary behaviours 3 months following cessation of a 12 week lifestyle intervention in men with prostate cancer on AST – preliminary results.

Year:

Session type:

Liam Bourke1, Robert Copeland2, John Saxton3, Derek Rosario4
1Barts and The London Shool of Medicine and Dentistry, Queen Mary University of London, London, UK, 2sheffield Hallam University, Sheffield, UK, 3University of East Anglia, Norwich, UK, 4University of Sheffield, Sheffield, -

Determinants of fatigue in men with prostate cancer undergoing androgen suppression therapy.

Year:

Session type:

Liam Bourke1, Helen Doll2, John Saxton2, Derek Rosario3
1Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK, 2University of East Anglia, Norwich, UK, 3University of Sheffield, Sheffield, UK

Sub-optimal serum levels of omega 3 and vitamin D appear to be common amoung cancer survivors – a pilot study

Year:

Session type:

Robert Thomas1,2, James Thomas2
1The Primrose Unit, Bedford Hospital, Bedford, UK, 2Cancernet-UK, London, UK

Black and South Asian women’s experiences of breast cancer: A qualitative study

Year:

Session type:

Geeta Patel1, Diana Harcourt1, Nichola Rumsey1, Habib Naqvi2
1University of the West of England, Bristol, UK, 2Bristol PCT, Bristol, UK

The role of the Neuro-Oncology Specialist Nurse: Coordinating the care of all patients with suspected brain tumour: A Re-audit

Year:

Session type:

Christopher Taylor2, Vanessa McGowan1, Gillian Hendry1, Phillip Kane1
1James Cook University Hospital, Middlesbrough, UK, 2Newcastle University, Newcastle Upon Tyne, UK

Supporting patients with suspected brain tumours: a re-audit of the Neuro-Oncology Specialist Nurses role

Year:

Session type:

Christopher Taylor1, Vanessa McGowan2, Gillian Hendry2, Phillip Kane2
1Newcastle University, Newcastle Upon Tyne, UK, 2James Cook University Hospital, Middlesbrough, UK

What is the best way to measure endpoints in evaluations on end of life care(EoLC): method guidance from an International online Delphi

Year:

Session type:

Hamid Benalia1, Catherine Evans1, Irene J. Higginson1
1King's College London, Cicely Saunders Institute, Department of Palliative Care, Policy and Rehabilitation, London, UK

Ascites in ovarian cancer (EOC): safety of free drainage and feasibility of day case paracentesis?

Year:

Session type:

Victoria Harding1, Sarah Ngan1, Ho Kwong Li1, Hanine Medani1, Sarah Blagden1, Hani Gabra1, Roshan Agarwal1
1Imperial College, London, UK

Does media coverage of scientific progress in cancer prevention promote screening uptake? An analysis of 134,564 invitations to assess change in uptake of bowel cancer screening in the period before and after the national media coverage of the Flexible Sigmoidoscopy trial results

Year:

Session type:

Christian von Wagner1, Siu Hing Lo1, Gemma Vart1, Julia Snowball2, Stephen Halloran2, Jane Wardle1
1University College London, London, UK, 2Southern Bowel Screening Hub, Guildford, UK

Colonoscopy or CT colonography for colorectal cancer screening: public preferences elicited using structured group discussions

Year:

Session type:

Christian von Wagner1, Samuel Smith1, Alex Ghanouni1, Molly Magee1, Steve Halligan1, Jane Wardle1
1UCL, London, UK

A single centre experience of a new acute oncology assessment unit to pro-actively manage complications of cancer systemic therapy

Year:

Session type:

Sharmistha Ghosh1, Elizabeth Crowther1, Yvonne Noble2, Michael Flynn1, Hartmut Kristeleit1
1Guys and St Thomas' NHS Foundation Trust, London, UK, 2South East London Cancer Network, London, UK

Delayed presentation of cervical cancer in young women: Developing and testing an interview-based measure

Year:

Session type:

Anita W W Lim1, Lindsay JL Forbes1, Julietta Patnick2, Kankipati Raju3, Adam N Rosenthal4, Amanda J Ramirez1
1King's College London, London, UK, 2NHS Cancer Screening Programmes, Sheffield, UK, 3Guy’s and St Thomas’ Hospital NHS Foundation Trust, London, UK, 4Bart’s Cancer Institute, London, UK

Breast cancer prevention program in china: attitude, knowledge and participation behaviour of Chinese women

Year:

Session type:

Tumenjavkhlan Sosorburam1, Xiao Ming2
1Tongji Medical College, Wuhan, China, 2Wuhan University, Wuhan, China

Cancer Research UK Stratified Medicine Informatics – a multi-site solution for the capture, storage, access and analysis of routinely collected clinical and genetic data to improve clinical outcomes

Year:

Session type:

Monica Jones1
1Cancer Research UK, London, UK

QUEST Perspective Study (QPS) to measure the understanding by patients and healthcare professionals of surgical breast reconstruction clinical trials: QUEST A & B 

Year:

Session type:

Zoe Winters1, Judith Mills2, Marie Emson2, Judith Bliss2, Robert Horne3
1University of Bristol, School of Clinical Sciences, Bristol, UK, CTSU-ICRClinical Trials & Statistic Unit, 3Centre for Behavioural Medicine, The School of Pharmacy, University of London, London, UK

The impact on the carbon footprint of service redesign of colon and prostate cancer follow up clinics in the Grampian region

Year:

Session type:

Leslie Samuel1, Robert Samuel2, Graham Macdonald1, Lynn Adams3
1Anchor Unit, Aberdeen Royal Infirmary, Aberdeen, Scotland, UK, 2Medical Faculty Office, Edinburgh University, Edinburgh, Scotland, UK, 3North of Scotland Cancer Network, Aberdeen Royal Infirmary, Aberdeen, Scotland, UK

Subnanosized lanthanide complexe reagents for MRI temperature monitoring and cancer diagnosis

Year:

Session type:

Sergey Babailov1, Vasiliy Kokovkin1, Pavel Stabnikov1
1Nikolayev Institute of Inorganic Chemistry SB RAS, Novosibirsk, Russia

A service evaluation of an early phase cancer clinical trials unit using a patient satisfaction questionnaire

Year:

Session type:

Teresa Lockett1, Sandie Wellman1, Verna Lavender2
1University Department of Oncology, Oxford, UK, 2Oxford Brookes University, Oxford, UK

Supporting the clinical research workforce in a local cancer research network: the role of the training & education lead

Year:

Session type:

Sean Chinnathumby1, Susan Palmer1, Ricky Sharma1
1Thames Valley Cancer Research Network, Oxford, UK

Electronic data capture – friend or foe of clinical research

Year:

Session type:

Deborah Beirne1,2, Catherine Fernandez1, Jenny Boards1,2, Tracey Rose1
1Leeds Teaching Hospitals NHS Trust, Leeds, UK, 2University of Leeds, Leeds, UK

Differing methods of delivering chemotherapy and managing toxicities across the UK: summary paper from the Association of Cancer Physicians New Consultants Group workshop

Year:

Session type:

Sally Clive1, Richard Baird2, Ashita Waterston3, Suzanne Darby4, Thomas Newsom-Davis5, Daniel Swinson6
1Edinburgh Cancer Centre, Edinburgh, UK, 2Royal Marsden Hospital, London, UK, 3Beatson Cancer Centre, Glasgow, UK, 4Weston Park Hospital, Sheffield, UK, 5Imperial College, London, UK, 6St James Hospital, Leeds, UK

[18F]-fluoromisonidazole (FMISO) PET-CT in the assessment of tumour perfusion and hypoxia with anti-angiogenic therapy in patients with metastatic renal cell carcinoma (mRCC)

Year:

Session type:

GDS Anandappa1, YT Hong1, J Westbrook1, V Barnes1, L Gray1, S Pinnock1, A Jonson1, R Smith1, FI Aigbirhio1, L Cookson3, DB Richards3, KM Fife1, AS Shaw1, W Lee2, HK Cheow1, NJ Bird1, TD Fryer1, DI Jodrell1, TGQ Eisen1
1NIHR Cambridge Biomedical Research Centre, Cambridge, UK, 2University of Pennsylvania School of Medicine, Philadelphia, USA, 3GlaxoSmithKline, Cambridge, UK

Clinical prediction of relapse and death in early breast cancer: Measuring the accuracy of a breast multidisciplinary team against the computer based prognostic model, Adjuvant! Online

Year:

Session type:

Janine Graham1, Albiruni RA Razak2, Louise Li1, Kate Sumpter1, Mark Verrill1
1Freeman Hospital, Newcastle upon Tyne, UK, 2Princess Margaret Hospital, Toronto, Ontario, Canada

Developing and testing a novel, evidence-based and user-tested toolkit for assessing and improving teamworking in cancer multidisciplinary teams

Year:

Session type:

Cath Taylor1, Katrina Brown2, Nick Sevdalis2, James Green3
1King's College London - Florence Nightingale School of Nursing and Midwifery, London, UK, 2Imperial College London, Centre for Patient Safety and Service Quality, London, UK, 3Whipps Cross University Hospital, London, UK

Water proton resonance frequency measured by magnetic resonance spectroscopy: a novel probe of tumour temperature and water exchange effects applied to childhood brain tumours

Year:

Session type:

Nigel Davies1,2, Maryam Saghafi2, Martin Wilson2,3, Theodoros Arvanitis2,3, Andrew Peet2,3
1University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK, 2University of Birmingham, Birmingham, UK, 3Birmingham Children’s Hospital NHS Foundation Trust, Birmingham, UK

Guidelines for the prevention and management of skin toxicities in patients receiving EGFR (epidermal growth factor) inhibitors

Year:

Session type:

Janet Davies1
1Clatterbridge Centre for Oncology, Wirral, UK, 2Liverpool Experimental Cancer Medicines Centre, Liverpool, UK

Evaluation of the key worker role in cancer services

Year:

Session type:

Karen Smith1, Jonathan Ling1, Ann Crosland1
1University of Sunderland, Sunderland, UK