719 abstracts found.



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A novel NGS library preparation method for detection of mutations and gene-fusions in circulating cell-free DNA and RNA

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Guoliang Fu1,Sarah Scaife1,Winnie Wu2
1Genefirst ltd,2genefirst ltd

Branched chain amino acids regulate the sensitivity of breast and ovarian cancer cells to paclitaxel

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Alan Richardson1,Mohammed Abed1,Suad Ibrahim2
1Keele University,2keele university

Modern Cancer Analytics: a natural language application to a complex biological landscape

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Jessica Black1,Paul O'Reilly2,Manuel Salto-Tellez2,Darragh McArt2
1Bioinformatics and Integromics Laboratory, CCRCB,2CCRCB, Queen's University Belfast

Breast cancer liver metastases: systematic review and time to event metanalysis with comparison between available treatments

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Daniela Votano1,Zaed Hamady1,Hassan Malik2
1Southampton General Hospital,2University Hospital Aintree NHS Foundation Trust

Fulvestrant +/- Vandetanib in advanced aromatase inhibitor resistant breast cancer

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Joanna Smith1,Zoe Hudson2,Tracie-Ann Madden1,Angela Casbard1,Laura Butlin1,Terri Kitson1,Mark Beresford3,Peter Barrett-Lee4,Sacha Howell5,David Cameron6,Julia Gee2,Jacinta Abraham4,Kay Wilson4,Bethan Tranter4,Gareth Griffiths7,Lesley Radley8,Robert Jones4
1Centre for Trial Research, Cardiff University,2Cardiff University,3Royal United Hospital Bath,4Velindre Cancer Centre,5The University of Manchester,6The University of Edinburgh,7University of Southampton Clinical Trials Unit,8c/o Centre for Trial Research, Cardiff University

COPELIA: A Randomised Phase II Trial of Cediranib in Combination with Paclitaxel or Olaparib Versus Weekly Paclitaxel Chemotherapy as Second-Line Therapy for Advanced/Metastatic Endometrial Cancer

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Jennifer Swettenham1,Gordon Jayson2,Robert Morgan2,Dilly Goonetilleke3,Richard Edmondson3,Ann White4,Angela Casbard1,Tracie-Ann Madden1,Nisa Khan2,Charlotte Wilhelm-Benartzi1,Catherine Rogers2,Rebecca Kristeleit5,Andrew Clamp2
1Cardiff University,2The Christie NHS Foundation Trust,3University of Manchester,4,5University College London

Identification and characterisation of cyclic peptide inhibitors of Ras/PI3K and Ras/Raf protein complexes

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Mohamed Ismail1,Julian Downward1
1The Francis Crick Institute

Predicting oesophageal cancer progression using genomic information in pre-malignant oesophageal tissues

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Sarah Killcoyne1,Eleanor Gregson1,David Wedge2,Rachel de la Rue1,Ahmad Miremadi1,Matthew Eldridge3,Moritz Gerstung4,Rebecca Fitzgerald1
1University of Cambridge,2University of Oxford,3Cancer Research UK Cambridge Institute,4European Bioinformatics Institute

Factors associated with survival in lung cancer patients admitted to intensive care: an analysis of the West of Scotland Critical Care and Cancer Patient Database

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Christopher Grant1,Philip McLoone1,Billy Sloan1,Kathryn Puxty2,Tara Quasim2,David Morrison1
1University of Glasgow,2Glasgow Royal Infirmary

Differences in endometrial cancer molecular portraits based on ethnicity in The Cancer Genome Atlas

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David Guttery1,Kevin Blighe1,Konstantinos Polymeros2,Paul Symonds1,Salvador Macip1,Esther Moss1
1University of Leicester,2Univerisyt of Leicester

Development of animal model to reduce anti-angiogenesis resistance in Glioblastoma

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Sreynet Srun1
1graduate school of cancer science and policy, national cancer center, south korea

IMvigor211: A global, open-label, phase III randomised study examining atezolizumab vs chemotherapy for platinum-treated advanced urothelial carcinoma

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Syed Hussain1,Thomas Powles2,Yohann Loriot3,Ignacio Durán4,Alain Ravaud5,Margitta M. Retz6,Nicholas J. Vogelzang7,Sanjeev Mariathasan8,Na Cui8,Christina L. Derleth8,Michiel S. van der Heijden9
1,2Barts Cancer Institute ECMC, Barts Health and the Royal Free NHS Trust, Queen Mary University of London,3Département de Médecine Oncologique, Université Paris-Saclay and Gustave Roussy,4Department of Medical Oncology, Hospital Universitario Virgen del Rocío and Institute of Biomedicine of Seville,5Hôpital Saint-André CHU and Department of Medical Oncology, Bordeaux University Hospital,6Department of Urology, Klinikum Rechts der Isar, Technical University Munich,7US Oncology Research, Comprehensive Cancer Centers of Nevada,8Genentech, Inc.,9Department of Medical Oncology, Netherlands Cancer Institute

Outcomes of everolimus + exemestane in ER+, HER2 neg, heavily pre-treated metastatic breast cancer: a real life multicentre experience

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Parth Desai1,Martin Hogg1
1Rosemere Cancer Foundation

Predictors of patient-related delay of oral cancer diagnosis in Bangladesh

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Md Zahid Ullah1,Jennifer NW Lim2,Marie-Ann Ha1,Bas Bueno-de-Mesquita3
1Anglia Ruskin University,2University of Wolverhampton,3Imperial College London

Anti-metastatic effects of adrenergic analogues on the triple-negative breast cancer cell line, MDA-MB-231

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Alice Lee1,Mustafa Djamgoz1
1Imperial College London

PET-CT in gynaecology malignancy exenterations: a 5 year experience

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Jeffrey Lim1,Sebastian Smolarek2,Nagindra Das3,Kerryn Lutchman-Singh3
1Great Western Hospitals NHS Foundation Trust,2Plymouth Hospitals NHS Trust,3Abertawe Bro Morgannwg University Health Board

Epigenetic sensitisation of NSCLC Cells to Common Chemotherapy Agents

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Ghaliah Alnefaie1,Israa Al-Humairi1,Jason Parsons1,John Field1,Lakis Liloglou1
1University of Liverpool

Dietary Polyphenols Influence Antimetabolite Agents: Methotrexate, 6-Mercaptopurine and 5-Fluorouracil in Leukemia Cell Lines

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Amani Mahbub1,Dr Nicola Jordan-Mahy2,Dr Neil Cross2,Prof Christine Le Maitre2,Dr Sarah Haywood2
1Umm Al Qura University,2Biomolecular Sciences Research Centre, Sheffield Hallam University

Mammographic density in women with a previous breast cancer: case control study

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Shuk Yee Choo1,Elaine Harkness2,Soujanya Gadde3,Yit Y Lim4,Anthony J Maxwell5,D Gareth Evans6,Anthony Howell6,Susan Astley5

1University of Manchester Medical School,2Centre for Imaging Sciences, Institute of Population Health, University of Manchester. Nightingale Centre and Genesis Prevention Centre, University Hospital of South Manchester, Manchester. The University of Manchester, Manchester Academic Health Science Centre, University Hospital of South Manchester NHS Foundation Trust, Manchester,3Nightingale Centre and Genesis Prevention Centre, University Hospital of South Manchester, Manchester.,4Centre for Imaging Sciences, Institute of Population Health, University of Manchester. Nightingale Centre and Genesis Prevention Centre, University Hospital of South Manchester, Manchester.,5Centre for Imaging Sciences, Institute of Population Health, University of Manchester. Nightingale Centre and Genesis Prevention Centre, University Hospital of South Manchester, Manchester. The University of Manchester, Manchester Academic Health Science Centre, University Hospital of South Manchester NHS Foundation Trust, Manchester. Manchester Breast Centre, Manchester Cancer Research Centre, University of Manchester, Christie Hospital, Withington, Manchester.,6Nightingale Centre and Genesis Prevention Centre, University Hospital of South Manchester, Manchester. The University of Manchester, Manchester Academic Health Science Centre, University Hospital of South Manchester NHS Foundation Trust, Manchester. Manchester Breast Centre, Manchester Cancer Research Centre, University of Manchester, Christie Hospital, Withington, Manchester.


Acceptability of Remote physiological monitoring (RPM) in cancer patients receiving anti-cancer systemic treatment (SACT): Single centre Pilot study

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Victoria Kunene1,Shaikh Muhammad Rana1,Aisha Farooqi1
1Queen Elizabeth hospital Birmingham

Digital communication use in Oncology Patients: Exploring current access and acceptibility of potential future interfaces

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Shahla Siddique1,Sally Appleyard1,Duncan Gilbert2
1Brighton & Sussex Medical Schools,2Brighton & Sussex University Hospitals

Patient stratification into robust cancer-cell intrinsic subtypes from colorectal cancer biopsies may inform prospective clinical trials

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Matt Alderdice1,Amy McCorry1,Claudio Isella2,Darragh McArt1,Susan Richman3,Dion Morton3,Philip Quirke3,Ultan McDermott3,Ian Tomlinson3,Graeme Murray3,Manuel Salto-Tellez1,Simon Gollins3,Richard Wilson1,Richard Adams3,Tim Maughan3,Enzo Medico2,Andrea Bertotti2,Mark Lawler1,Philip Dunne1
1Centre for Cancer Research and Cell Biology, Queen's University Belfast,2Università degli Studi di Torino,3Stratification in COloRecTal Cancer (S:CORT) Consortium

Association of circulating markers of immortality and cellular senescence with survival in advanced gastro-oesophageal adenocarcinoma patients

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Alan Bilsland1,Sofie Degerman2,Mattius Landfors2,Jennifer Walker3,Carol McCormick3,Eilidh McCulloch3,Liz-Anne Lewsley3,Antonia MacMillan4,Martin MacLeod5,Jamie Stobo3,James Paul3,Göran Roos2,T.R. Jeffry Evans3,Fiona Thomson3,W. Nicol Keith3
1University of glasgow,2Umea University,3university of glasgow,4University of Glasgow,5Beatson West of Scotland Cancer Centre

Assessing an anti-Pro-static antibody as a potential candidate for an antibody-drug conjugate to target aggressive prostate cancer

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Aimy Nguyen Chi1
1Swansea University Medical School

Is 3 months more cost-effective than 6 months in Colorectal Cancer? Evidence from the Short Course Oncology Therapy study

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José Robles-Zurita1,Kathleen Boyd1,Andrew Briggs1,Jim Paul2,Tim Iveson3,Andrea Harkin1,Karen Allan2,John McQueen2,Claire Scudder4,Mark Saunders5,Rachel Kerr6,Andrew Haydon7
1University of Glasgow,2Cancer Research UK Clinical Trials Unit,3Southampton University Hospitals NHS Trust,4OCTO, University of Oxford,5The Christie Hospital, Manchester,6University of Oxford,7The Alfred Hospital

ICON7: ovarian cancer, platinum second-line chemotherapy and overall survival

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Adrian Cook1,Andrew Embleton1,Gordon Jayson2,Richard Kaplan1,Amit Oza3,Max Parmar1,Jacobus Pfisterer4,Eric Pujade-Lauraine5,Timothy Perren6
1University College London,2University of Manchester,3Princess Margaret Cancer Centre,4AGO Study Group,5Université Paris Descartes,6St James University Hospital

National Cancer Research Institute Teenage, Young Adult and Germ Cell Health Services Research Subgroup: Historical achievements and emerging strategy

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Lorna Fern1,Rachel Dommett2,Rebecca Ling3,Lisa McCann4,Sue Morgan5,Stark Dan6,Rachel Taylor7,Anne-Sophie Darlington8,Max Williamson9,Lara Veitch10
1,2University Hospitals Bristol,3Institute of Cancer Research,4University of Strathcylde,5Leeds General Infirmary,6University of Leeds and Leeds Teaching Hospitals NHS Trust,7University College London Hospitals,8University of Southampton,9University College London,10Kings College London

Breast Reconstruction in a Regional Breast Cancer Network: Ten years on.

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Mark Tatterton1
1Royal Bournemouth Hospital

Outcomes for patients not suitable for radical surgery following neo-adjuvant chemotherapy in Upper Gastrointestinal cancers.

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Eleanor Smith1,Aung Tin1,David Wilson2,Nick Wadd1
1James Cook University Hospital,2James Cook University Hospital Trust

The Rockwood Geriatric Clinical Frailty Scale is a more discriminatory tool for assessing older cancer patients compared with standard oncology performance status scales.

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Mary Denholm1,Pippa Corrie2,Wendi Qian3,Joanna Hampton4
1Cambridge University Hospitals NHS Foundation Trust,2Department of Oncology, Cambridge University Hospitals NHS Foundation Trust,3Cambridge Cancer Trials Centre, Cambridge Clinical Trials Unit,4Department of Medicine for the Elderly, Cambridge University Hospitals NHS Foundation Trust

Health professionals’ views on multi-disciplinary head and neck cancer clinics: benefits for patients, professionals and the NHS

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Sally Appleyard1,Eleanor Crossley2,Andrew Pelser3,Richard Simcock2
1Brighton & Sussex Medical Schools,2Brighton & Sussex University Hospitals,3Brighton & Sussex Hospitals

Health economic benefits of blood-based microRNA testing in testicular germ cell tumours

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Henry Aubrey1,Chantelle Bell2,Dan Charytonowicz2,Maeline Ferret2,Keith Tsui2,Nick Coleman2,Matthew Murray2,Rachel Atfield3,Ed Wilson2
1,2The University of Cambridge,3Cambridge Enterpirse

The Implementation of a Regional Adjuvant Zoledronate Service (AZS) for Early Breast Cancer: A Review of the First 10 Months.

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Joanna Connor1,Joanne Cliff1,Aimee Davies1,Helen Innes1
1Clatterbridge Cancer Centre

Capacity and Resource Planning for Oesophago-Gastric Cancer Services: The Importance of a Comprehensive Approach.

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Rohan Pinto1,Ross McAllister1,Bilal Alkhaffaf1
1Central Manchester University Hospitals NHS Foundation Trust

Geographical recruitment to cancer clinical trials in NHS Grampian

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Kirsty Shearer1
1Scottish Cancer Research Network

telemedicine in a clinical research facility to provide patients consistent, efficient and local service

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Navdeep Kaur Brar1,Mark Grey2,Stephanie Cornthwaite1
1lancashire teaching hospitals NHS trust,2Blackpool Teaching Hospitals NHS trust

Evaluation of a novel programme supporting community delivery of denosumab to patients with metastatic bone disease

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Jack Broadfoot1,Chloe Holden1,Caroline Archer1
1Portsmouth Hospitals NHS Trust

FACTORS THAT INFLUENCE DELAYS IN HEALTH CARE SEEKING, DIAGNOSIS AND TREATMENT FOR BREAST CANCER PATIENTS IN UGANDA

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Allen NAAMALA MAYANJA1,Warren Phips2,Fred Matovu3,Fred Machyo Okuku4
1UGANDA CANCER INSTITUTE,2Hutchinson Cancer Research centre- Uganda,3Makerere University,4Uganda Cancer Institute

The knowledge of nurses collecting samples for clinical trials: evaluation and education

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Emma Johnson1,Sandra Wellman2,Sarah Blagden2
1University of Oxford,2Oxford University Hospitals NHS Trust

A central review of monitoring reports to measure the performance and monitoring workload of a cancer study site

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Neha Vaid1,Anne Butterfield1,Linda Ward2,Sandie Wellman1
1Oxford University Hospitals NHS Trust,2Oxford University

What predicts patient non-attendance at urgent referral appointments for suspected cancer?

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Rebecca Sheridan1,Steven Oliver2,Lisa Dyson3,Victoria Allgar2,Karl Atkin3,Trish Green4,Geoff Hall5,Una Macleod6,Philip Melling7,Martin Waugh7,Peter Knapp2
1University of York,2Department of Health Sciences, University of York and the Hull York Medical School,3Department of Health Sciences, University of York,4Centre for Health and Population Sciences, Hull York Medical School,5Leeds Teaching Hospitals NHS Trust and the University of Leeds,6Hull York Medical School,7Leeds Teaching Hospitals NHS Trust

Salvage surgery for local regrowth following external beam radiotherapy followed by contact X-ray brachytherapy and ‘Watch & wait’ for rectal cancer.Do we compromise the chance of cure?

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Arthur Sun Myint1,Fraser Smith2,Helen Wong1,Karen Whitmarsh1,Raj Sripadam1,Chris Rao3,Kate Perkins1,Mark Pritchard4
1Clatterbridge Cancer Centre,2Royal Liverpool and Broadgreen University Hospital,3Department of Surgery, University Hospital, Lewisham, London, UK,47.Institute of Translational Medicine, University of Liverpool, UK

Breast Cancer cause specific five year survival data for Patients treated in Liverpool Royal Hospital

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Salma Mohamed1,Chris Holcombe2
1Royal Liverpool University Hosptial,2Royal liverpool University Hospital

A Protocol for an Evaluation Study of Patient Follow-Up and Cancer Clinical Trial Complexity: the EFACCT study.

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Helene Markham-Jones1,Prof. Christopher Bridle1,Prof. Tanweer Ahmed2
1University of Lincoln,2United Lincolnshire Hospitals Trust

Suspected Neutropenic Sepsis Admission at Royal Derby Hospital: A Retrospective Audit

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Aurelien Hostalery1,Anna Stubbs1
1University of Nottingham

Supporting trainee oncologists with the emotional demands of caring for cancer patients

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Mareike Thompson1,Sara Lightowlers1,Susannah Hunt1
1Addenbrooke's Hospital, Cambridge

Radium-223 – An overview of nurse-led service in Beatson West of Scotland Cancer Centre

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Gail Buchanan1,Norma Sidek2
1Beatson West of Scotland Cancer Centre,2Beatson West of Scootland Cancer Centre

Electronic data capture of QoL PROMS: an exploratory study in patients commencing palliative treatment for Prostate Cancer.

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Sally Appleyard1,Duncan Gilbert2
1Brighton & Sussex Medical Schools,2Brighton & Sussex University Hospitals

Evaluating the impact of a straight to test pathway for patients with oesophageal gastric cancer in the East Midlands

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James Jones1,James Catton2,Paul Leader3,Lesley Brewer4,Dominick Shaw1
1East Midlands Academic Health Science Network,2Nottingham University Hospital Trust,3Derby Teaching Hospitals NHS Foundation Trust,4East Midlands Clinical Networks

Informed consent for research mandated image guided biopsies – are patients provided with adequate information?

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Theresa Taylor Emberton1
1The Christie Hospital