215 abstracts found.



Characterizing ERG-Mediated Transcriptional Reprogramming of Prostatic Epithelial Cells towards a Cancer Stem Cell Phenotype

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Manju Sharma1,Yubin Guo2,Robert Bell2,Michael Cox2
1Vancouver Prostate centre,2Vancouver Prostate Centre

Heterogeneous addiction to TGFβ signalling in life threatening cSCC’s arising in RDEB patients

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Jasbani Dayal1,Andrew South2,Julio Salas-Alanis3,John McGrath4,Irene Leigh5,Karen Blyth6,Susan Mason6,Jemima Mellerio7,Christina Gruber8,Gareth Inman6
1Ninewells Hospital Medical School,2Thomas Jefferson University,3Universidad de Monterrey,4King's College London,5Queen Mary University of London,6The Beatson Institute for Cancer Research,7St John's Institute of Dermatology,8Paracelsus Medical University Salzburg

Epithelial-to-mesenchymal transition signature assessment in colorectal cancer quantifies tumour stromal content rather than true transition

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Amy McCorry1,Maurice Loughrey2,Mark Lawler1,Philip Dunne1
1Queen's University Belfast,2Belfast Health and Social Care Trust

Functional dissection of the role of Myc in Pancreatic tumorigenesis

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Nathiya Muthalagu1,Jennifer Morton1,Owen Sansom1,Daniel Murphy2
1Beatson Institute for cancer research,2University of Glasgow, Beatson Institute for cancer research

Identifying breast-to-brain metastasis-associated gene mutations by whole exome sequencing

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Mark Morris1,Ivonne Olivares2,Timothy Dawson3,Kate Ashton3,Charles Davis3,Michael Jenkinson4,Andrew Brodbelt5,Angel Armesilla2,Tracy Warr2
1University of Wolverhamnpton,2University of Wolverhampton,3Royal Preston Hospital,4The Walton centre,5The Walton Centre

Kinome screening identifies fibroblast PIK3Cδ to be involved in triple-negative breast cancer (TNBC) invasion

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Georgios Giamas1,Teresa Gagliano1,Viviana Vella1,Giulia Bresciani1,Kamila Bienkowska1,Frances Pearl1
1University of Sussex

Phenotypic subtypes associated with distinct therapeutic targets: Towards personalized medicine for patients with colorectal cancer

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Antonia Roseweir1,James Park1,Meera Patel1,Arfon Powell2,Paul Horgan1,Donald McMillan1,Joanne Edwards1
1University of Glasgow,2Cardiff University

Sperm associated antigen 5 (SPAG5) predicts resistance to endocrine therapy and sensitivity to chemotherapy in oestrogen receptor positive (ER+) breast cancer (BC): A tool for BC precision medicine

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Tarek Abdel-Fatah1,Graham Ball2,Amy McCart Reid3,Peter Simpson4,Sunil Lakhani4,Lorinc Pongor5,Balazs Gyorffy5,Paul Moseley1,Andrew Green6,Carlos Caldas7,Rebekah Webb1,Ian Ellis6,Stephen Chan1
1Clinical Oncology Department, University of Nottingham Hospitals NHS Trust,2John van Geest Cancer Research Centre, Nottingham Trent University, UK,3The University of Queensland, UQ Centre for Clinical Research, Herston, 4029, QLD, Australia,4The University of Queensland, School of Medicine, Herston, 4006, QLD, Australia,5MTA TTK Lendület Cancer Biomarker Research Group, Semmelweis University 2nd Department of Pediatrics, Budapest, Magyar, Hungary,6Histopathology department, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, UK,7University of Cambridge, and 5Cancer Research UK, Cambridge Research Institute, UK

Roles of VRK3 in regulation of PARP1 stability and PARP inhibitor sensitivity

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Han Seong Hyun1
1Pohang University of Science and Technology

SMC1A: a novel candidate DNA damage biomarker in hair follicles

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Surbhi Kaul1,Alan Bilsland2,Chantevy Pou2,Joanna Birch2,Anthony Chalmers2,Fiona Thomson2,Jeff Evans2
1Institute of Cancer Science, Wolfson Wohl Cancer Research Centre, University of Glasgow,2University of Glasgow

XIST and miRNA sequestration: Insights into lncRNA-mediated gene regulation

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Erin A Marshall1,Greg L Stewart1,Adam P Sage1,Wan L Lam1,Carolyn J Brown2
1BC Cancer Research Centre,2University of British Columbia

Selective vulnerability of colorectal cancer (CRC) organoids to hypoxia-mimetic drug

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Chiara Asselborn1,Kevin Myant1,Alex von Kriegsheim1
1University of Edinburgh

Identification of C1orf106 as a TGF-β target gene which promotes clonogenicity and anchorage-independent growth

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Lauren Strathearn1,Susan Mason2,Lindsay Spender1,Karen Blyth2,Gareth Inman1
1University of Dundee,2CRUK Beatson Institute

Antibiotic use and efficacy of small molecule inhibitors in patients with advanced cancer

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Grace Tan1,Nadina Tinsley2,Cong Zhou1,Shaun Villa2,Paul Lorigan2,Fiona Blackhall2,Matthew Krebs2,Louise Carter2,Fiona Thistlethwaite2,Andrew Hughes1,Natalie Cook2
1University of Manchester,2Christie NHS Foundation Trust

Blood vessel abnormalities in glioblastoma: characterization at baseline, at recurrence and following radiotherapy suggest a therapy induced phenotype

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Anastasia Widyadari1,Anastasia Widyadari2,Michael Grant2,Aruna Chakrabarty3,Valerie Speir4,Susan Short2,Georgia Mavria2
1Leeds Institue of Medical Sciences,2Leeds Institute of Medical Sciences,3LEEDS TEACHING HOSPITALS NHS TRUST,4University of Aberdeen