22 abstracts found.



Reduction of full-length transglutaminase 2 (TG2-L) expression decreases cisplatin chemoresistance in an MCF-7 model of hormone-positive breast cancer

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Peter Coussons1,Ebidor Lawani-Luwaji1,Claire Pike1
1Anglia Ruskin University

Inhibition of prostate cancer cell growth, motility and ability to alter monocyte/macrophage lineage commitment by a novel TRAF6 inhibitor

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Denise Giovana Carrasco Gonzalez1,Ryan T. Bishop2,Antonio Maurizi3,Silvia Marino4,Anna Sparatore5,Mattia Capulli3,Aymen I. Idris1
1University of Sheffield,2Moffitt Cancer Centre,3University of L’Aquila,4Indiana University,5University of Milano

Nischarin and ShcD interaction:  A novel mechanism to control cell migration and affecting patients’ overall survival

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Samrein Ahmed1
1University of Sharjah

Serum hormones and prostate cancer incidence and mortality in UK Biobank

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Ruth Travis1,Eleanor Watts1,Georgina Fensom1,Aurora Perez-Cornago1,Anika Knuppel1,Naomi Allen1,Marc Gunter2,Richard Martin3,Karl Smith Byrne2,Neil Murphy2,Kostas Tsilidis4,Tim Key1
1University of Oxford,2International Agency for Research on Cancer,3University of Bristol,4University of Ioannina

Critical role of autophagy induction in tumor growth and activation of cancer metabolism by leptin in breast cancer Cells

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Nirmala Tilija Pun1,Duc-Vinh Pham1,Pawan Kumarraut1,Ananda Baral1,Su-min Lee1,Thi-Hong-Van Tran2,Pil-Hoon Park*1
1Yeungnam University,2Yeungnam Univesity

Does augmenting the complement system improve Rituximab induced cell lysis?

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Katy Plant1
1Cardiff University School of Medicine

Genomic Profiling of Saudi patients with Colorectal Cancer using Next Generation Sequencing

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Saleh Alghamdi1,Alhanouf Alomani2,Bader Almuzaini2,Abdullah Alsharm1,Fida Aljaser3
1KFMC,2KAIMRC,3KSU

Mapping Cellular Subpopulations within Triple Negative Breast Tumors Provides a Tool for Cancer Sensitization to Radiotherapy

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Ariel M. Rubinstein1,Heba Alkhatib1,Swetha Vasudevan1,Shira Stefansky1,Tamar Peretz-Yablonsky2,Avital Granit2,Amichai Meirovich2,Nataly Kravchenko-Balasha1
1Hebrew University of Jerusalem,2Hadassah Medical Center

The effects of indigenous South African plant extracts (Cotyledon orbiculata and Tulbaghia. Violacea) on triple negative breast cancer cells

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Mohammed Alaouna1,Rodney Hull2,Clem Penny3,Zodwa Dlamini4
1witwatersrand university,2Pretoria University,3University of the Witwatersrand,4University of Pretoria

CD99 regulation of cancer cell dynamics and tumour formation

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Adam Odell1,Aarren Mannion2,Alison Taylor3,Pam Jones3,Graham Cook3
1York St. John University,2Karolinska Institute,3University of Leeds

Optimisation of a Selection Strategy for Drug Resistance Osteosarcoma Cell Lines

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Kaan Low1,Frank Hills1,Helen Roberts1,Britta Stordal1
1Middlesex University

High-content Profiling in Oesophageal Adenocarcinoma Identified Selectively Active Compounds for Repurposing and Novel Drug Discovery

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Rebecca Hughes1,Richard Elliott2,Ashraff Makda2,Robert O'Neill3,Ted Hupp2,Neil Carragher2
1University of Edinburgh,2UNIVERSITY OF EDINBURGH,3Cambridge Oesophagogastric Unit

Endothelial cell function is disrupted by viral inactivation of p53

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Adam Odell1,Aarren Mannion2,Pam Jones3,Graham Cook3
1York St. John University,2Karolinska Institute,3University of Leeds

Combination of caloric restriction and lysine-specific demethylase 1 (LSD1) inhibition in the treatment of acute myeloid leukemia

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Rani Pallavi1,Luca Mazzarella1,Tiphanie Durfort1,Elena Gatti1,Bruno Achutti Duso1,Massimo Stendardo1,Luciano Giaco1,Ciro Mercurio2,Mario Varasi2,Marco Giorgio1,Saverio Minucci1,Pier Giuseppe Pelicci1
1European Institute of Oncology,2FIRC Institute of Molecular Biology

Mamma globin-A peptide specific cytotoxic CD8+T Lymphocyte Response Against Breast cancer cells.

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Sarika Mehta1,Sarika Mehta2
1nil,2lab technician

Transcriptome-wide Mendelian randomisation identifying brain-specific causal genes influencing glioma

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Jamie Robinson1,Richard Martin1,Amy Howell1,Spiridon Tsavachidis2,Georgina Armstrong2,Caroline Relton1,Melissa Bondy2,Jie Zheng1,Kathreena Kurian1
1University of Bristol,2Baylor College of Medicine

Phospho-protein arrays: a useful tool for identification of kinase inhibitors targets in personalized treatment of pediatric refractory solid tumors

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Jakub Neradil1
1Faculty of Medicine, Masaryk University

Adiponectin suppresses inflammasomes activation in breast cancer cells via sestrin-2 induction

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Duc-Vinh Pham1,Pawan Kumar Raut1,Ananda Baral1,Su-min Lee1,Thi-Hong-Van Tran1,Pil-Hoon Park1
1Yeungnam University

A ‘Beyond Genomics’ Approach to Precision Oncology: Development of a Protein Profiling Platform for Tumor and Tumor Organoid Samples

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Christoph Sachse1,Gerrit Erdmann1,Anja Briese1,Przemyslaw Dudys1,Ulrike Pfohl2,Markus Templin3,Christian Regenbrecht4
1NMI TT Pharmaservices,2Institute of Pathology University Clinic Magdeburg,3NMI Natural and Medical Sciences Institute at the University of Tübingen,4Institute of Pathology University Clinic Magdeburg, CELLphenomics GmbH, ASC Oncology GmbH

Hedgehog signals inhibitors reverse sorafenib resistance in patient-derived organoids models with hepatocellular carcinoma

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Siqi Wang1,Jiye Zhu1,Zhao Li1,Yang Wang1
1Department of Hepatobiliary Surgery, Peking University People’s Hospital

Protein Phosphatase 4 Regulatory Subunit 3A regulates leukemic cell survival independent of PP4 catalytic subunit

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Mirna Mourtada-Maarabouni1,Nadieh Kavousi2
1Keele University,2University of Keele

Genome-wide CRISPR screen in 3D intestinal organoids to define novel mechanisms critical for colorectal tumorigenesis

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Patrizia Cammareri1,Eline Janssen2,Caroline Billard2,Michela Raponi2,Victoria Gudino2,Stuart Aitken2,Alfonso Bolado Carrancio2,Alex Von Kriegsheim2,Abdolrahman Nateri3,Kevin Myant2
1ECRC,2Cancer Research UK Edinburgh Centre, The Institute of Genetics and Molecular Medicine,3Cancer Biology Unit, Division of Cancer & Stem Cells. School of Medicine, University of Nottingham