48 abstracts found.



Assessing the immunomodulatory activity of cancer prevention agents using an ex vivo tumour explant model

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Sam Khan1,Ankur Karmokar1,Zahirah Sidat2,Nalini Foreman1,David Moore3,Anne Thomas1,Karen Brown1
1Leicester Cancer Research Centre, Robert Kilpatrick Clinical Sciences Building, University of Leicester, Leicester,2Hope Clinical Trials Facility, Leicester Royal Infirmary, Leicester,3University College London Hospitals NHS Foundation Trust, London

Coffee consumption by type and risk of digestive cancer: A large prospective cohort study.

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Kim Tu Tran1,Helen Coleman1,Úna McMenamin1,Chris Cardwell1
1Queen's University Belfast

Depressive symptoms and participation in breast and cervical cancer screening

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Claire Niedzwiedz1,Kathryn Robb1,Srinivasa Vittal Katikireddi1,Jill Pell1,Daniel Smith1
1University of Glasgow, Glasgow, UK

Meat intake and cancer risk: prospective analyses in UK Biobank

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Anika Knuppel1,Keren Papier1,Georgina K. Fensom1,Paul N. Appleby1,Julie A. Schmidt1,Tammy Y. N. Tong1,Ruth C. Travis1,Timothy J. Key1,Aurora Perez-Cornago1
1Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford

Identifying health workers’ knowledge and beliefs regarding cervical cancer and screening, and its impact on screening utilisation in Gujarat, India

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Amanpreet Mundair1
1University of Leeds

Adolescent cancer risk exposures predict intermediate cancer risk exposures at age 24 years: A longitudinal analysis using ALSPAC data

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Caroline Wright1,Richard Martin1,Rona Campbell1,Ruth Kipping1,Matthew Hickman1,Jon Heron1
1University of Bristol

The association between fasting blood glucose and lung cancer risk in Chinese: a population-based prospective study

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Zhangyan Lyu1,Ni Li2,Fengwei Tan2,Jiang Li2,Chunqing Lin2,Hongda Chen2,Jiansong Ren2,Jufang Shi2,Kai Su2,Fang Li2,Xiaoshuang Feng2,Luopei Wei2,Xin Li2,Yan Wen2,Gang Wang3,Shuohua Chen4,Shouling Wu4,Min Dai2,Jie He2
1National Cancer Center, Beijing, China, National Clinical Research Center for Cancer, Beijing, China, Cancer Hospital, Beijing, China, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China,2National Cancer Center / National Clinical Research Center for Cancer / Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College,3Kailuan General Hospital,4Kailuan (group)

Metabolic syndrome and renal cell cancer risk in Chinese males: a population-based prospective study.

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Xin Li1,Gang Wang2,Xiaoshuang Feng1,Zhangyan Lyu1,Luopei Wei1,Yan Wen1,Shuohua Chen3,Shouling Wu3,Hongda Chen1,Ni Li1,Min Dai1,Jie He1
1National Cancer Center/ National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College,2Kailuan General Hospital,3Health Department of Kailuan (Group)

Participant views of taking part in a tailored cancer awareness intervention: Preliminary participant interview findings from the Awareness and Beliefs About Cancer Trial (ABACus3)

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Harriet Quinn-Scoggins1,Yvonne Moriarty2,Fiona Wood1,Julia Townson2,Kate Brain1
1Division of Population Medicine, School of Medicine, Cardiff University,2Centre for Trials Research, Cardiff University

Curcumin as an agent for cancer prevention in colorectal cancer

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Sam Khan1,Ankur Karmokar1,Zahirah Sidat2,Nalini Foreman1,David Moore3,Anne Thomas1,Karen Brown1
1Leicester Cancer Research Centre, Robert Kilpatrick Clinical Sciences Building, University of Leicester, Leicester,2Hope Clinical Trials Facility, Leicester Royal Infirmary, Leicester,3University College London Hospitals NHS Foundation Trust, London

Breast adipocyte diameter, adult weight gain, anthropometry and lifestyle habits in women with breast cancer

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Sofia Laforest1,Francine Durocher1,André Tchernof1,Caroline Diorio1
1Université Laval

Impact of body fatness and metabolic traits on colorectal cancer

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Emma Vincent1,Caroline Bull1,Joshua Bell1,Neil Murphy1,Nicholas Timpson1,Marc Gunter2
1University of Bristol,2International Agency of Research on Cancer

Smoking cessation for cancer prevention: Can incentives play a role? Evidence from a Cochrane review

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Caitlin Notley1,Sarah Gentry2,Jonathan Livingstone-Banks3,Linda Bauld4,Rafael Perera3,Jamie Hartman-Boyce3
1Norwich Medical School, Norwich, UK,2University of East Anglia, Norwich, UK,3Cochrane, University of Oxford, Oxford, UK,4University of Edinburgh, Edinburgh, UK

Population-based genetic testing of 16,000 healthy Australian women for germline mutations in hereditary breast and ovarian cancer predisposition genes

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Ian Campbell1,Lisa Devereux1,Simone Rowley1,Na Li1,Alison Trainer1,Paul James1
1Peter MacCallum Cancer Centre

Serum biomarkers of iron status and risk of primary liver cancer: A systematic review and meta-analysis.

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Kim Tu Tran1,Helen Coleman1,Robert McCain1,Chris Cardwell1
1Queen's University Belfast

Resveratrol’s effects on a BRAF mutant mouse model of colorectal carcinogenesis

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Grandezza Aburido1,Hong Cai1,Raj Singh1,Don Jones1,Rob Britton1,Karen Brown1
1University of Leicester

Predictive risk factors of venousthromboembolism (VTE) associated withperipherally inserted central catheters(PICC) in ambulant solid cancer patients:retrospective single Centre cohort study

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Osamah al-asadi1
1nhs

Genetic inhibition of HMG-CoA reductase and epithelial ovarian cancer risk: a Mendelian randomization analysis

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James Yarmolinsky1,Caroline Bull1,Emma Vincent1,Jamie Robinson1,Axel Walther1,George Davey Smith1,Sarah Lewis1,Caroline Relton1,Richard Martin1
1University of Bristol

Longitudinal Changes in Fasting Blood Glucose and Cancer Risk in Chinese Population Without Diabetes

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Xiaoshuang Feng1,Gang Wang2,Zhangyan Lyu1,Shuohua Chen3,Luopei Wei1,Xin Li1,Yan Wen1,Yuheng Chen1,Shuanghua Xie1,Hong Cui1,Hongda Chen1,Jiang Li1,Chunqing Lin1,Jiansong Ren1,Jufang Shi1,Shouling Wu4,Min Dai1,Ni Li1,Jie He1
1National Cancer Center / National Clinical Research Center for Cancer / Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College,2Kailuan general hospital,3Health department of Kailuan Group,4Health Department of Kailuan Group

Statin use and risk of liver cancer: evidence from two population-based studies.

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Kim Tu Tran1,Úna McMenamin1,Helen Coleman1,Chris Cardwell1,Peter Murchie2,Lisa Iversen2,Amanda Lee2,Aaron Thrift3
1Queen's University Belfast,2University of Aberdeen,3Baylor College of Medicine

Exploring the causal role of the human gut microbiome on colorectal cancer: Application of Mendelian randomization

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Kaitlin Wade1,Long Nguyen2,Amit Joshi2,Robert Carreras-Torres3,Andrew Chan2,Marc Gunter4,Yi Lin5,Graham Casey6,Jane Figueiredo7,Stephen Gruber8,Jochen Hampe9,Heather Hampel10,Mark Jenkins11,Temitope Keku12,Ulrike Peters13,Catherine Tangen14,Anna Wu15,David Hughes1,Malte Rühlemann16,Jeroen Raes17,Nicholas Timpson1

1MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School,2Massachusetts General Hospital,3IDIBELL Bellvitge Biomedical Research Institute,4International Agency for Research on Cancer,5Fred Hutchinson Cancer Research Center,6Center for Public Health Genomics,7Department of Medicine, Samuel Oschin Comprehensive Cancer Institute,8Department of Preventive Medicine, USC Norris Comprehensive Cancer Center,9Department of Medicine I, University Hospital Dresden,10Division of Human Genetics, Department of Internal Medicine, The Ohio State University,11Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health,12Center for Gastrointestinal Biology and Disease, University of North Carolina,13Public Health Sciences Division, Fred Hutchinson Cancer Research Center,14SWOG Statistical Center, Fred Hutchinson Cancer Research Center,15University of Southern California,16Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel,17Center for Microbiology, VIB, Department of Microbiology and Immunology, Rega Instituut

Investigating causal relationships between sleep characteristics and risk of breast cancer: a Mendelian randomization study

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Rebecca Richmond1,Emma Anderson1,Hassan Dashti2,Samuel Jones3,Jacqueline Lane2,Caroline Relton1,Marcus Munafò4,Debbie Lawlor1,Martin Rutter5,Richa Saxena2,Mike Weedon3,Richard Martin1,George Davey Smith1

1University of Bristol,2Massachusetts General Hospital, Boston,3University of Exeter,4University of Bristol, UK,5University of Manchester

Effective chemoprevention strategies in APC driven mouse models of intestinal tumourigenesis

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Michael Hodder1,Patrizia Cammareri1,Dennis Timmerman1,Owen Sansom1

1CRUK Beatson Institute

Communicating messages about alcohol-related BC risk: the Alcohol and Breast Cancer (ABC) study

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Emma Miller1,Paul Ward1,Ian Olver2,Samantha Meyer3,Darlene McNaughton1,Lillian Mwanri1,Kristen Foley1,Sara Macdonald4
1Flinders University,2University of South Australia,3University of Waterloo,4University of Glasgow

Mediterranean diet adherence and risk of pancreatic cancer: a pooled analysis of two Dutch cohorts

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Maya Schulpen1,Petra H. Peeters2,Piet A. van den Brandt1
1Maastricht University,2University Medical Centre Utrecht

European Cancer Incidence is Significantly Reduced in Huntington’s Disease Patients – Unravelling it’s Protective Mechanisms.

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Paul McNulty1,Raviram Ramesh1,Richard Pilcher1,Renata Neciunaite1,Lesley Jones1,Alys Hughes1,Daniel Farewell1,Timothy Stone1,Peter Holmes1

1Cardiff University

A cluster randomised feasibility study of an adolescent incentive intervention to increase uptake of HPV vaccination

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Alice Forster1,Victoria Cornelius2,Lauren Rockliffe1,Laura Marlow1,Helen Bedford1,Jo Waller1
1UCL,2Imperial College London

A novel application of two-step Mendelian randomization: applying the results of small feasibility studies of interventions to infer causal effects on clinical endpoints

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Meda R. Sandu1,Rhona Beynon1,Rebecca Richmond1,Diana L. Santos Ferreira1,J Athene Lane1,Richard M. Martin1
1University of Bristol

Beliefs about medication and uptake of preventive therapy in women at increased risk of breast cancer: Results from a multi-centre prospective study

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Rachael Thorneloe1,Rob Horne2,Lucy Side3,Michael Wolf4,Samuel Smith1
1Leeds Institute of Health Sciences, University of Leeds,2Centre for Behavioural Medicine, School of Pharmacy, University College London,3Wessex Clinical Genetics Service, University Hospitals Southampton,4Division of General Internal Medicine and Geriatrics, Northwestern University

Acting on BRCA: Breaking down barriers to save lives. Recommendations for the UK Government on BRCA testing and patient management from Ovarian Cancer Action.

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Marie-Claire Platt1,Joanne Stanford1,Georgina Tharp1
1Ovarian Cancer Action

Modulation of Phospho Tensin Homolog (PTEN) in Cancer Cells and Lipid Peroxides in Peripheral Blood Mononuclear Cells (PBMCs) Following Exposure to Flavonoids

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William Boadi1,William Boadi1,Alekzander Garcia1,Elbert Myles1
1Tennessee State University

Cancer, risk and decision making in vulnerable women: An exploratory study

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Sarah Hanson1,Duncan Gilbert2,Rebecca Landy3,Grace Okoli4,Cornelia Guell5
1UEA,2Brighton and Sussex University Hospitals,3National Cancer Institute,4Queen Mary University London,5European Centre for Environment and Human Health, University of Exeter Medical School, Truro

Increasing Dietary Soy for Breast Cancer Prevention: Building the Evidence for a Soy Intervention Study among Asian Women

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Nadia Rajaram1,Mikael Eriksson2,Geok Lin Khor3,Cheng Har Yip4,Per Hall2,Nur Aishah Mohd Taib5,Weang Kee Ho6,Soo Hwang Teo1
1Cancer Research Malaysia,2Karolinska Institutet,3International Medical University,4Subang Jaya Medical Centre,5University of Malaya Medical Centre,6University of Nottingham Malaysian Campus

Diet, nutrition, physical activity and the risk of aerodigestive cancers from the WCRF/ AICR Third Expert Report

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Isobel Bandurek1,Giota Mitrou1,Ifigeneia Bourgiezi1,Michelle McCully1,Susannah Brown1,Nigel Brockton2,Deirdre McGinley-Gieser2,Martin J. Wiseman1,Kate Allen1,Emily Almond1
1World Cancer Research Fund International,2American Institute for Cancer Research

Deciphering preventive and prognostic biomarkers of liver cancer

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Salvatore Papa1,Nathan Lee1,Concetta Bubici2
1Cell Signaling and Cancer Laboratory, Leeds Institute of Cancer and Pathology, Faculty of Medicine and Health, University of Leeds, St James’ University Hospital, Beckett Street, Leeds, UK,2College of Health and Life Sciences, Department of Life Sciences, Institute of Environment, Health and Societies, Division of Biosciences, Brunel University London, Uxbridge, UK

Genetic determinants underlying the variation in response to cancer chemoprevention agents

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Salwa Almayouf1,David B.H. Barton1,Yue Hu1,Edward J. Louis1,Steven S. Foster1
1University of Leicester

Exercise and Metformin intervention for men with prostate cancer: a feasibility study

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Hilary Taylor1,Lucy Hackshaw-McGeagh1,Richard Martin1,Athene Lane1
1University of Bristol

Piperlongumine, a novel treatment option to overcome BRAF inhibitor resistance in melanoma

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Sharavan Ramachandran1,Neel Fofaria1,Sahdeo Prasad1,Sanjay Srivastava1
1Texas Tech University Health Sciences Center

A two nation’s comparative study of perception towards prevention and early detection of breast cancer: with role of collagen as histopathological differentiators

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Abdelbaset Elasbali1
1University of Jouf

Investigating the effects of dietary and physical activity interventions on the metabolome of men with prostate cancer: The PrEvENT randomised controlled trial

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Meda R. Sandu1,Diana L. Santos Ferreira1,Rebecca Richmond1,Lucy Hackshaw-McGeagh1,Rhona Beynon1,Richard M. Martin2,J Athene Lane1
1University of Bristol,2university of Bristiol

Conversation Time: Development of an Ecological Momentary Assessment tool for exploring predictors of receptiveness to a discussion about physical activity and cancer prevention at cancer screening

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Rebecca Beeken1,Claire Stevens2,Rachael Thorneloe1,William Goodman2,Mangesh Thorat3,Meghana Kamble4,Grace Okoli5,Katherine Bradbury6,Daniel Powell7
1University of Leeds,2University College London,3Queen Mary University of London,4University of East Anglia,5Kings College London,6University of Southampton,7University of Aberdeen

Systematic assessment of risk factors for epithelial ovarian cancer: a Mendelian randomization analysis of up to 66,450 women

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James Yarmolinsky1,Caroline Relton1,Kenneth Muir2,Artitaya Lophatananon2,Usha Menon3,Aleksandra Gentry-Maharaj3,Axel Walther1,Jie Zheng1,George Davey Smith1,Richard Martin1,Sarah Lewis1
1University of Bristol,2University of Manchester,3University College London

Patterns in pre-diagnostic metabolite profile are associated with risk of more aggressive prostate cancer: a prospective study of 3057 matched case-controls sets from EPIC

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Julie Schmidt1,Georgina Fensom1,Sabina Rinaldi2,Augustin Scalbert2,Paul Appleby1,David Achaintre2,Audrey Gicquiau2,Marc Gunter2,Pietro Ferrari2,Nada Assi2,Tim Key1,Ruth Travis1
1University of Oxford,2International Agency for Research on Cancer

Using Mendelian randomization to investigate the causal effect of diet on prostate cancer

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Sarah Lewis1
1University of Bristol

Identifying smoking-independent targets for lung cancer prevention: a systematic Mendelian randomization study

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Nabila Kazmi1,Kaitlin Wade1,Aayah Nounu1,Ryan Langdon1,Vanessa Tan1,James Yarmolinsky1,Jie Zheng1,Gibran Hemani1,Robert Torres2,Mattias Johansson2,Tom Gaunt1,Rayjean Hung3,Chris Amos4,Sarah Lewis1,Richard Martin1,Paul Brennan2,Caroline Relton1,George Smith1,Phili Haycock1
1University of Bristol,2International Agency for Research on Cancer (IARC),3Sinai Health System,4Baylor College of Medicine

A novel gene expression score accurately predicts biochemical recurrence of prostate cancer after radical prostatectomy using TCGA dataset

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Nahaa Alsubaie1
1Wolfson Institute of Preventive Medicine

Identification of novel pyrazolopyrimidine compounds that modulate the shelterin complex and telomere length regulation via phosphoglycerate kinase 1 and stress sensor DJ1

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W. Nicol Keith1,Alan Bilsland2,Yu Liu2,Andrew Turnbull3,David Sumpton4,Katrina Stevenson2,Claire Cairney2,Susan Boyd5,Jon Roffey3,David Jenkinson3,W. Nicol Keith2
1University of glasgow,2University of Glasgow,3Cancer Research Technology,4Beatson Institute for Cancer Research,5CompChem Solutions Ltd

What is fuelling overweight and obesity and which policy actions are needed? : WCRF/ AICR Third Expert Report

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Michelle McCully1,Giota Mitrou1,Susannah Brown1,Isobel Bandurek1,Louise Meincke1,Bryony Sinclair1,Ifigeneia Bourgiezi1,Nigel Brockton2,Deirdre McGinley-Gieser2,Martin J. Wiseman1,Kate Allen1
1World Cancer Research Fund International,2American Institute for Cancer Research