809 abstracts found.



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Cancer care in 2011 is disease based, not discipline based

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Murray Brennan1
1Memorial Sloan-Kettering Cancer Center, New York, USA

The different genetic alterations between Western and Chinese prostate cancers indicate the aetiology

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Xueying Mao1, Nuria Coll Bastus1, Lara Boyd1, Yongwei Yu2, Guoping Ren1,3, Lius Beltran4, Tim Oliver1, Bryan Young1, Daniel Berney1, Yong-Jie Lu1
1Queen Mary University of London, London, UK, 2Changhai Hospital, Shanghai, China, 3Zhijiang University Medical College, Hangzhou, China, 4Whipps Cross Hospital, London, UK

Identification and characterisation of GSK3b-phosphorylation dependent interactions of tumour suppressor gene Fbxw7

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Ranjithmeon Muraleedharan1, Bradley Spencer-Dene2, Abdolrahman S. Nateri1
1Cancer Genetics and Stem Cell Group, School of Clinical Sciences, University of Nottingham, Nottingham, UK, 2Experimental Pathology Laboratory, CR-UK London Research Institute, London, UK

Mechanisms of monoubiquitination in the Fanconi Anemia tumour suppressor pathway.

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Jennifer Miles1, Ateesh Sidhu1, Helen Walden1
1CR-UK London Research Institute, London, UK

Population-based data on lung cancer from the UK: The National Audit and beyond

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Michael Peake1
1Glenfield Hospital, Leicester, UK

Modern radiotherapy techniques and progress in non-small cell lung cancer

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Suresh Senan1
1VU University Medical Center, Asterdam, The Netherlands

Patient-specific mathematical radiation oncology: Integrating clinical imaging and modeling to improve outcomes

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Kristin Swanson1
1University of Washington, Seattle, WA, USA

Aberrant cell signalling in cancer

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Chris Marshall1
1Institute of Cancer Research, London, UK

Introduction: Genomics analysis of intratumour heterogeneity and drug resistance mechanisms in cancer medicine

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Charles Swanton1
1CR-UK London Research Institute, London, UK

Stratified medicine in colorectal cancer: Current state and challenges ahead

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Sabine Tejpar1
1Digestive Oncology and Center for Human Genetics, University Hospital Leuven, Leuven, Belgium

Breast cancer intratumour heterogeneity: A challenge for personalised medicine

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James Hicks1
1Cold Spring Harbor Laboratory

Evolution of the cancer genome

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Michael R. Stratton1
1Wellcome Trust Sanger Institute, Cambridge, UK

Dissecting mechanisms of cancer drug resistance through functional genetics

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Rene Bernards1
1Netherlands Cancer Institute, Amsterdam, The Netherlands

Intratumoural heterogeneity and the evolution of drug resistance in high-grade serous ovarian cancer

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James Brenton1
1Cancer Research UK Cambridge Research Institute, Cambridge, UK

Introduction: Genetic predisposition to cancers – future implications for selective screening, surveillance and management

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Ros Eeles1
1ICR, Sutton, UK

Predicting cancer risk using genetic variation

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Douglas Easton1
1University of Cambridge, Cambridge, UK

Genetic predisposition to cancer – implications for selective screening

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Harry de Koning1
1Erasmus MC & Johns Hopkins Bloomberg School of Public Health, Rotterdam, The Netherlands

Using germline susceptibility testing to inform the treatment of newly-diagnosed cancer patients

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Mark Robson1
1Memorial Sloan-Kettering Cancer Center, New York, NY, USA

Introduction: Genomic instability and cancer: Lessons from analysis of Bloom’s syndrome

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Ian Hickson1
1University of Copenhagen, Copenhagen, Denmark

Regulation of recombination-mediated DSB repair and its importance for genome stability

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Stephen West1
1London Research Institute, South Mimms, UK

The human mismatch repair interactome

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Josef Jiricny1
1Institute of Molecular Cancer Research, Zurich, Switzerland

The BRCA1-BRCA2 pathway of homologous recombination

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Simon Powell1
1Memorial Sloan-Kettering, New York, USA

Introduction: Lung cancer treatment: We have lift off!

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Marianne Nicolson1
1Aberdeen Royal Infirmary, Aberdeen, UK

Lessons from the small DNA tumour viruses

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Daniel DiMaio1
1Yale University School of Medicine, New Haven, CT, USA

Strategies for radiosensitisation targetting the tumour microenvironment

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Ruth Muschel1
1University of Oxford, Oxford, UK

Mechanisms of human papillomavirus-induced malignancy

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Lawrence Banks1
1International Centre for Genetic Engineering and Biotechnology, Trieste, Italy

The role of functional imaging in developing strategies towards a patient-tailored approach in prostate cancer

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Karin Haustermans1
1University Hospital, Leuven, Belgium

Mechanisms of Epstein-Barr virus lymphomagenesis

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Martin Rowe1
1University of Birmingham, Birmingham, UK

Introduction: Deregulated expression of the translation machinery in cancer

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Robert White1
1Beatson Institute for Cancer Research, Glasgow, UK

Translating the PI3K/mTOR pathway and translational control to radiation therapy

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Robert Schneider1
1New York, NY, New York, NY, USA

Translational control of pancreatic carcinogenesis

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Stéphane Pyronnet1
1INSERM U1037, Toulouse, France

Deregulation of gene expression at the level of translation in diffuse large B-cell lymphoma

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Anne Willis1
1MRC Toxicology Unit, Leicester, UK

Introduction: Biomarker validation and adaptive clinical trial design

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Caroline Dive1
1Paterson Institute for Cancer Research, Manchester, UK

Fit-for-purpose biomarker validation

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Howard Scher1
1Memorial Sloan-Kettering Cancer Center

Biomarkers in early drug development

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Josep Tabernero1
1Val d'Hebron University Hospital, Barcelona, Spain

Adaptive trial design that incorporates biomarkers

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Lucinda Billingham1
1MRC Midland Hub for Trials Methodology Research & Cancer Research UK Clinical Trials Unit, University of Birmingham

Introduction: Cancer awareness and early diagnosis: International perspectives

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Amanda Ramirez1
1King's College London, London, UK

International differences in cancer awareness and beliefs: The International Cancer Benchmarking Partnership

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Lindsay Forbes1
1King's College London, London, UK

Cancer awareness and early diagnosis in Denmark: A rewarding intervention?

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Peter Vedsted1
1Research Centre for Cancer Diagnosis in Primary Care, Aarhus University, Denmark

Public attitudes and awareness of cancer risks and early detection: a Canadian perspective

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Heather Bryant1
1Canadian Partnership Against Cancer, Toronto, ON, Canada

Introduction: The first century of human tumour virology

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Chris Boshoff1
1University College London Cancer Institute

Introduction: Clinical and translational approaches to radiotherapy

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Gillie McKenna1
1Gray Institute for Radiation Oncology & Biology, University of Oxford, Oxford, UK

The tumour vasculature in metastatic CRC: Beyond the obvious

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Lee Ellis1
1MD Anderson Cancer Center, Houston, Texas, USA

Exploiting knowledge of DNA damage repair to improve treatment for patients with colorectal cancer

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Ricky Sharma1
1University of Oxford, Oxford, UK

Molecular selection of therapy in colorectal cancer: Clinical trials

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Richard Wilson1
1Queen's University Belfast

Introduction: Paediatric oncology: Survivorship from Childhood Cancer

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Adam Glaser1
1St James's Hospital, Leeds, UK

Detection of the late effects of cancer: Surveillance and the role of genetic risk factors

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Kevin Oeffinger1
1Memorial Sloan-Kettering Cancer Center, New York, NY, USA

Cardiac toxicity in survivors of childhood cancer

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Leontien C. Kremer1
1University of Amsterdam, Amsterdam, The Netherlands

Screening, preventative and chronic disease care in cancer survivors

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Nada Khan1
1University of Oxford, Oxford, UK

Introduction: Phosphoinositol signalling and cancer

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Bart Vanhaesebroeck1
1Barts Cancer Centre, London, UK