¹University of Liverpool,²Paul Strickland Scanner Centre, Mount Vernon Hospital, Middlesex, UK,³Royal Liverpool and Broadgreen University Hospitals NHS Trust,⁴Faculty of Medicine, University of Southampton, Southampton, UK.,⁵Department of Surgery, University Hospital Southampton NHS Foundation Trust, Southampton, UK.,⁶Department of Radiology, Portsmouth Hospitals NHS Trust, Portsmouth, UK.,⁷Department of Gastrointestinal Surgery, Leeds Teaching Hospitals NHS Trust, Leeds, UK.,⁸Department of Radiology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.,⁹Department of Surgery, Glasgow Royal Infirmary - NHS Greater Glasgow and Clyde, Glasgow, UK.,¹⁰Department of Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.,¹¹Barts Cancer Institute, Barts and the London, London, UK.,¹²Gastrointestinal and Lymphoma Unit, Royal Marsden NHS Foundation Trust, London, UK.,¹³Institute for Liver and Digestive Health, University College London Hospitals NHS Foundation Trust, London, UK.,¹⁴Department of Surgery, Royal Free London NHS Foundation Trust, London, UK.,¹⁵Department of Surgery, Royal Blackburn Hospital- East Lancashire Hospitals NHS Trust, Blackburn,UK.,¹⁶Department of Surgery, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.,¹⁷Paul Strickland Scanner Centre, Mount Vernon Hospital, Middlesex, UK.,¹⁸Department of Mathematics and Statsistics, Lancaster University, Lancaster, UK,¹⁹Department of Mathematics and Statsistics, Lancaster University, Lancaster, UK.,²⁰Centre for Health Economics and Medicines Evaluation, Bangor University, Lancaster, UK.,²¹Centre for Health Economics and Medicines Evaluation, Bangor University, Bangor, UK.,²²Liverpool Cancer Research UK Cancer Trials Unit, University of Liverpool, Liverpool, UK,²³Department Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK.

¹University College London,²UCL,³NCI

¹Memorial Sloan-Kettering Cancer Center and Weill Cornell Medical College,²Oncology Institute of Veneto IRCCS,³University of Colorado Cancer Center,⁴Maria Sklodowska-Curie Memorial Cancer Center & Institute of Oncology,⁵Hospital de la Timone,⁶Texas Oncology-Baylor Charles A. Sammons Cancer Center,⁷University of Michigan,⁸Department of Dermatology, University of Essen,⁹European Institute of Oncology,¹⁰Cross Cancer Institute,¹¹Universitäts Spital,¹²Tasman Oncology Research,¹³Netherlands Cancer Institute,¹⁴University Hospital of Siena,¹⁵Peter MacCallum Cancer Centre,¹⁶Bristol-Myers Squibb,¹⁷Royal Marsden Hospital,¹⁸Dana-Farber Cancer Institute

¹Queen Elizabeth Hospital Birmingham

¹CCRCB Queen's University Belfast,²QUB

¹The Francis Crick Institute, London, UK / Human Genome Laboratory, Department of Human Genetics, University of Leuven, Leuven, Belgium,²Laboratory of Reproductive Genomics, Department of Human Genetics, University of Leuven, Leuven, Belgium / Single-cell Genomics Centre, Wellcome Trust Sanger Institute, Hinxton, UK,³Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway / K.G. Jebsen Center for Breast Cancer Research, Institute for Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway,⁴Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK,⁵Institute for Genomics & Systems Biology and Department of Human Genetics, University of Chicago, Chicago, Illinois, USA / (Present address) Laboratory of Genetics, University of Wisconsin, Madison, Wisconsin, USA,⁶Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway / Division of Surgery and Cancer Medicine, Department of Oncology, Oslo University Hospital, Radiumhospitalet, Oslo, Norway / (Present address) Department of Oncology, Akershus University Hospital, Lørenskog, Norway,⁷Department of Pathology, Oslo University Hospital, Radiumhospitalet, Oslo, Norway,⁸Laboratory of Reproductive Genomics, Department of Human Genetics, University of Leuven, Leuven, Belgium,⁹Institute for Genomics & Systems Biology and Department of Human Genetics, University of Chicago, Chicago, Illinois, USA,¹⁰Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway / (Present address) Department of Pediatric Research, Women and Children's Division, Oslo University Hospital, Rikshospitalet, Oslo, Norway,¹¹K.G. Jebsen Center for Breast Cancer Research, Institute for Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway / Division of Surgery and Cancer Medicine, Department of Oncology, Oslo University Hospital, Radiumhospitalet, Oslo, Norway

¹National Cancer Research Institute,²University College London Hospitals NHS Foundation Trust

¹University of Manchester,²Manchester Royal Infirmary,³Mount Vernon Hospital

¹Glasgow Centre for Cancer Research

¹Cardiff University

¹Clatterbridge Cancer Centre,²Royal Liverpool and Broadgreen University Hospital,³Department of Cellular and Molecular Physiology,University of Liverpool

¹NHS

¹Centre for Cancer Research and Cell Biology,²Centre for Cancer Research and Cell Biology, Queen's University Belfast,³Northern Ireland Cancer Centre, Belfast Health and Social Care Trust

¹Ministry of Health, Sri Lanka,²Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.,³German Cancer Research Center (DKFZ), Heidelberg, Germany.,⁴The Christie NHS Foundation Trust,⁵Universtiy of Leicester, United Kingdom,⁶University of Leicester, United Kingdom,⁷Institute of Cancer Sciences, University of Manchester, UK.

¹University of Michigan

¹NCRI,²NCRI Consumer Forum

¹Clatterbridge Cancer Centre

¹UT MD Anderson Cancer Center,²MD Anderson

¹University of New South Wales

¹Cancer Research UK Manchester Institute

¹MAASTRO clinic/Maastricht University

¹Media Futures

¹University of Leeds,²University of Birmingham,³University Hospitals Bristol NHS Foundation Trust,⁴University of Bristol / University Hospitals Bristol NHS Foundation Trust,⁵University of Leeds / Leeds Teaching Hospitals NHS Trust

¹University of Zurich

¹University of Warwick

¹University of Manchester

¹Stanford University

¹University of St Andrews

¹University of Leicester

¹Policy Research Centre for Cancer Prevention, Cancer Research UK

¹Guy's and St Thomas' NHS Trust Foundation,²King's College London,³Karolinska Institute,⁴Karolinske Institute

¹MRC Biostatistics Unit

¹National Cancer Institute

¹Hasselt University

¹Cancer Research UK Clinical Trials Unit, University of Birmingham,²Leeds Teaching Hospitals NHS Trust, Leeds,³Royal Marsden Hospital and Institute of Cancer Research, London,⁴The Christie NHS Foundation Trust, Manchester,⁵King's College London, and Guy's and St Thomas’ NHS Foundation Trust, London,⁶Cancer Research UK, London,⁷Royal Marsden Hospital and Imperial College, London,⁸Institute of Immunology and Immunotherapy, University of Birmingham

¹Newcastle University

¹CRUK Manchester Institute,²Central Manchester NHS Foundation Trust (CMFT),³Christie NHS Foundation Trust, Manchester

¹Cancer Research UK Cambridge Institute, University of Cambridge

¹University of Nottingham

¹Swinburne University of Technology

¹VU University Medical Center

¹University of Sheffield Medical School,²ScHARR, University of Sheffield,³Sheffield Hallam University,⁴The University of Nottingham,⁵University of Leicester,⁶University of Liverpool,⁷The University of Sheffield,⁸Brighton and Sussex Medical School

¹Frimley Health,²

¹University Hospitals of North Midlands Stoke-on-Trent

¹University of Southampton

¹The Royal Marsden Hospital

¹The Royal Marsden Hospital

¹London Breast Institute

¹King's College London,²Guy's and St Thomas' NHS Foundation Trust,³Sagentia,⁴Lighpoint Medical Ltd,⁵St George's University Hospital NHS Foundation Trust

¹Royal Liverpool University Hospital,²University of Liverpool