661 abstracts found.



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Development of the Resource Utilisation Inventory for Economic Evaluation (RUtInETM)

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Kyriaki Giorgakoudi1
1City, University of London and NIHR Biomedical Research Centre at the Royal Marsden NHS Foundation Trust and the Institute of Cancer Research, London

CRISPR/Cas9 mediated PTEN knockout induces EMT through Akt/β-Catenin/Snail signaling in non-small cell lung carcinoma cells

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Perumal Elumalai1,Kim So Youn1,Yeun Jun Chung1
1The Catholic University of Korea

Can we sub-select patients to be tested within the current NICE indications for Oncotype in a South Yorkshire/Derbyshire early breast cancer population?

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Laura Kendal1,Alexander Burnett1,Matthew Winter1,Caroline Wilson1
1Sheffield Teaching Hospitals

Colorectal cancer stratification using a novel high throughput transcriptomic assay

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Gerard Quinn1,Wendy Allen1,Sarah Maguire1,Daniel Longley1,Bruce Seligmann2,Simon McDade1
1Queen's University Belfast,2Biospyder Technologies

Metastatic Renal Cancer: How many patients are we treating?

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Kate Fife1,Jessica Clifton2,Sarah Nolasco1,Athena Matakidou1,Sarah Welsh1,Tim Eisen1
1Cambridge University Hospitals NHS Foundation Trust,2Cambridge University Medical School

POSNOC – Positive Sentinel Node: Adjuvant therapy alone versus adjuvant therapy plus clearance or axillary radiotherapy(ISRCTN54765244, Clinicaltrials.gov NCT02401685)

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Amit Goyal1
1Royal Derby Hospital

Epithelial-to-mesenchymal transition signature assessment in colorectal cancer quantifies tumour stromal content rather than true transition

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Amy McCorry1,Maurice Loughrey2,Mark Lawler1,Philip Dunne1
1Queen's University Belfast,2Belfast Health and Social Care Trust

Investigating Aspirin and Ticagrelor for the prevention of tumour cell-induced platelet aggregation.

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Meera Chauhan1,David Adlam1,Anne Thomas1,Alison Goodall1,Joy Wright1
1University of Leicester

METASTASIS GENE DISCOVERY:- A WHOLE GENOME CRISPR KNOCKOUT SCREEN AND MURINE ENDOSCOPY IDENTIFIES FOXF1 AS A SUPPRESSOR OF COLORECTAL CANCER METASTASIS

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Lennard YW Lee1,Connor Woolley2,Ian Tomlinson2
1Institute of Cancer Sciences, Universityof Birmingham,2Institute of Cancer Sciences, University of Birmingham

Diet, nutrition, physical activity and the risk of aerodigestive cancers from the WCRF/ AICR Third Expert Report

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Isobel Bandurek1,Giota Mitrou1,Ifigeneia Bourgiezi1,Michelle McCully1,Susannah Brown1,Nigel Brockton2,Deirdre McGinley-Gieser2,Martin J. Wiseman1,Kate Allen1,Emily Almond1
1World Cancer Research Fund International,2American Institute for Cancer Research

Characterising the metabolic fate of (2S, 4R)-4[¹⁹F]-fluoroglutamine in cancer cells using ¹⁹F-MRS

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Nhat Nguyen1,Andreas Doepner1,Graham Smith1,Yuen-Li Chung1
1The Institute of Cancer Research

Developing new paradigms for overcoming drug resistance in cancer using novel humanised mouse models

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Colin Henderson1,Yury Kapelyukh1,Kenneth MacLeod2,De Lin1,Aileen McLaren1,Roland Wolf1
1University of Dundee,2Concept Life Sciences

Structure-based virtual screening identifies pranlukast as a CD49f antagonist that reduces stemness in MDA-MB-231 breast cancer cells

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Marco Velasco-Velazquez1,Inés Velázquez-Quesada1,Angel Ruiz-Moreno1,Diana Casique-Aguirre1,Charmina Aguirre-Alvarado1,Fabiola Cortés-Mendoza1,Marisol de la Fuente-Granada1,Mayra Pérez-Tapia2,Aliesha Gonzalez-Arenas1,Aldo Segura-Cabrera3
1National Autonomous University of Mexico,2National Polytechnic Institute,3EMBL-EBI

OVPSYCH2: A randomised study of psychological support versus standard of care following chemotherapy for ovarian cancer

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Sarah Blagden1,Sarah Blagden2,Gianfilippo Bertelli3,Eleni Frangou4,Chrissie Butcher5,Sharon Love4,Melanie McKean6,Ros Glasspol7,Audrey Cook8,Shibani Nicum2,Rosemary Lord9,Michelle Ferguson10,Rene Roux2,Maria Martinez11,Susanna Black12,Anwen James12,Helen Palmer13,Sarah Hughes12,Claire Marriott13,Lesley Howells14
1University of Oxford,2Churchill Hospital, University of Oxford, Oxford,3Sussex Cancer Centre, Brighton,4University of Oxford Centre for Statistics & Medicine,5Oncology Clinical Trials Office, University of Oxford,6Edinburgh Cancer Centre, Western General Hospital, Edinburgh,7Beatson West of Scotland Cancer Centre, Glasgow,8Gloucester Oncology Centre, Cheltenham,9Clatterbridge Cancer Center, Wirral,10Ninewells Hospital, Dundee,11Department of Surgery and Cancer, Imperial College London,12Maggie's Swansea Centre,13Maggie's Oxford Centre,14Maggie's Centres Research

An exploratory study on the use of game-based learning using Microsoft Kinect to teach oncology phase I clinical trial designs

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Alan Bilsland1,Caroline Kelly2,Jennifer Roccisana3,James Paul2,Rob Jones2,Joanne Edwards3,Antonia Roseweir4,Torsten Stein3,Katherine West5
1Institute of Cancer Science, Wolfson Wohl Cancer Research Centre, University of Glasgow,2Cancer Research UK Clinical Trials Unit, Institute of Cancer Science, University of Glasgow,3Institute of Cancer Science, University of Glasgow,4School of Medicine, Dentistry and Nursing, University of Glasgow,5School of Life Sciences, University of Glasgow

Information Giving in Breast Cancer: A Service Review of the Mid-Yorks NHS Trust

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Georgina Appleyard1,Hannah Jones1,Jay Naik2
1University of Leeds,2Mid Yorks NHS

Exploring experiences of referral for diagnostic investigations and attitudes towards the new Faster Diagnostic Standard

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Marianne Coleman1,Georgia Black2,Dorothee Amelung1,Emily Power3,Katriina Whitaker1
1University of Surrey,2University College London,3Cancer Research UK

Analysis of putative biomarkers of resistance to retinoids in neuroblastoma cells and tumor tissue samples

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Viera Dobrotkova1,Petr Chlapek1,Katerina Adamkova2,Marta Jezova3,Pavel Mazanek3,Jaroslav Sterba3,Renata Veselska4
1Masaryk University, International Clinical Research Center, St. Anne’s University Hospital Brno,2Masaryk University,3University Hospital Brno, Masaryk University,4Masaryk University, International Clinical Research Center, St. Anne’s University Hospital Brno, University Hospital Brno, Masaryk University

Glyoxalase 1 expression, copy number and survival analysis in clinical treatment of breast cancer

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Muhanad Alhujaily1,Mingzhan Xue1,Naila Rabbani1,Paul Thornalley1
1University of Warwick

Improving the intra-operative diagnosis of high-grade glioma using a fluorescence biomarker – result of the UK NCRI GALA-BIDD study

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Colin Watts1,Keyoumars Ashkan2,Michael Jenkinson3,Kathreena Kurian4,Wendi Qian5,Stephen Price5,Tomasz Matys6,Gail Doughton5,Andrea Machin5,Josephine Jung2,Ibrahim Jalloh3,Chloe Harman5,Katrina Gatley5,Gemma Young5,Richard Hardy5,Alimu Dayimu7

1University of Birmingham,2Kings College Hospital,3University of Liverpool,4Southmead Hospital,5Cambridge University Hospitals NHS Foundation Trust,6University of Cambridge,7Shandong University


Understanding the role of multimorbidity on symptomatic presentation and early diagnosis of cancer

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Katriina Whitaker1
1University of Surrey

Circulating tumour DNA as a tool to guide clinical decision making in melanoma

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Rebecca Lee1
1CRUK MI

Lung Cancer IO – hi ho

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Mary O'Brien1
1Royal Marsden NHS Hospital

Effect of a low-intensity PSA-based screening intervention on prostate cancer mortality: the CAP randomized clinical trial

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Richard Martin1
1University of Bristol

The role of individual and system factors on inequalities in cancer care and outcomes

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Bernard Rachet1
1London School of Hygiene and Tropical Medicine

Acting on BRCA: Breaking down barriers to save lives. Recommendations for the UK Government on BRCA testing and patient management from Ovarian Cancer Action.

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Marie-Claire Platt1,Joanne Stanford1,Georgina Tharp1
1Ovarian Cancer Action

Use of Virtual Reality in patient education improves understanding of radiotherapy treatment and reduces anxiety: a retrospective single-centre study

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Vanita Gandhi1,Shrinivas Kuthpady1,Sarah Needleman1
1Royal Free NHS Trust

Performance Status, hypoalbuminemia and leucocytosis as prognostic factors for Cancer of Unknown Primary (CUP)

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Bradley Lonergan1,Marwan Bukhari1,David Fyfe1
1University Hospital of Morecambe Bay (UHMB) Trust

The impact of sarcopenia on mortality following elective colorectal cancer resection.

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Daniel Dolan1,Katrina Knight1,Susan Moug2
1University of Glasgow,2NHS Greater Glasgow & Clyde

MLH1 Promoter Hypermethylation: Development and Preliminary Validation of a Methylation-Specific High Resolution Melt Curve Analysis (MS-HRM) Assay for use in a Lynch Syndrome Pre-Screen Pathway

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Diana Pelka1,Sasha Hansel1,Ben Poskitt1,David Moore1,Phil Bennett1,Gareth Gerrard1
1Sarah Cannon Molecular Diagnostics, HCA Healthcare UK

ROS and mitochondrial genetic abnormalities as novel indicators for anti-cancer drug sensitivity

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Tarek Zaidieh1,Qian An2
1Portsmouth University,2University of Portsmouth

Renal function assessment in head and neck cancer patients receiving chemotherapy: An audit of local practice.

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Anna Anosova1,Nida Pasha1,Suzanne Douglas2,Kevin Chiu1,Catherine Lemon1,Kee Howe Wong1
1Mount Vernon Cancer Centre,2Mount Vernon Cancer Centre Nuclear Medicine Department

Translocation renal cell carcinoma: Evidence for activity of current VEGF-directed therapies.

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Claire Pettinger1,Jahangeer Malik2,Marie O'Donnell3,Stefan Symeonides4
1University of Edinburgh,2Edinburgh Cancer Centre, NHS Lothian,3Department of Pathology, NHS Lothian,4University of Edinburgh & Edinburgh Cancer Centre

Malignant Spinal Cord Compression (MSCC) – How can we do better?

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Sarah Slater1,Saurabh Vohra1,Robert Rulach1,Carrie Featherstone1,Derek Grose1,Cathy Hutchison1
1Beatson West of Scotland Cancer Centre

Development of the biomarker panel risk score for early detection of pancreatic cancer

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Oleg Blyuss1,Stephen W. Duffy1,Tatjana Crnogorac-Jurcevic1
1Queen Mary University of London

Anticancer Properties of the Foliose Lichen, Heterodermia diademata (Taylor) Awasthi against Breast Cancer Cell Lines

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Jijo Francis1
1Sacred Heart College

A decision analysis of screening for renal cancer using focused renal ultrasound

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Sabrina Rossi1,Grant Stewart1,Edward Wilson1
1University of Cambridge

Development of lung metastases in new animal models of OSCC

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Sabrina Marcazzan1,Ali Dadbin2,Giulia Brachi3,Elvin Blanco2,Elena Maria Varoni1,Giovanni Lodi1,Mauro Ferrari2
1University of Milan,2Houston Methodist Research Institute,3Politecnico di Torino

Therapeutic potential of novel thiosemicarbazones in pediatric oncology: combined treatment with vinca alkaloids.

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Silvia Chovanova1,Maria Krchniakova2,Petr Chlapek2,Jaroslav Sterba3,Des Richardson4,Renata Veselska5
1,2Department of Experimental Biology, Faculty of Science, Masaryk University, Brno; International Clinical Research Center, St. Anne's University Hospital, Brno,3Department of Pediatric Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno,4Molecular Pharmacology and Pathology Program, Department of Pathology and Bosh Institute, University of Sydney, Sydney,5Department of Experimental Biology, Faculty of Science, Masaryk University, Brno; International Clinical Research Center, St. Anne's University Hospital, Brno; Department of Pediatric Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno

Public awareness of and responses to media coverage of invitation errors in the Breast Screening Programme in England: A population survey

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Alex Ghanouni1,Christian von Wagner1,Jo Waller1
1University College London

Dental pre-assessment prior to bisphosphonates for breast cancer: a quality improvement project in Glasgow

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Yun Yi Tan1,Lucy Scott1,Sophie Barrett1
1Beatson West of Scotland Cancer Centre

Is radiological sarcopenia a biomarker for poor outcome in advanced lung cancer?

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Iain Phillips1,Adele Hug1,Lindsey Allan1,Laurensius Mainsiouw1,Louise Newton1,Emily Hotson2,Jeewaka Mendis2,Veni Ezhil1
1Royal Surrey County Hospital,2University of Surrey

Association of Vitamin D receptor and group-specific component gene polymorphisms with prostate cancer

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Farhad Mashayekhi1,Alireza Lotfabadi2
1University of Guilan, Rasht,2University of Guilan, Iran

Hoping against hope: Are patients’ understanding and expectations about therapeutic aims of novel drugs similar to their oncologists?

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Lucy Matthews1,Shirley May1,Valerie Jenkins1,Susan Catt1,Valerie Shilling1,Lesley Fallowfield1
1SHORE-C

The relationship between features of the tumour microenvironment and survival in primary operable breast cancer

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Elizabeth Morrow1,Fadia Gujam2,Zara Mohammed Adams3,Antonia Roseweir2,Joanne Edwards2
1,2University of Glasgow,3Omar El-Mukhtar University

Dysfunctional mitochondria are exported from myeloma cells to the bone marrow microenvironment

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Yu Sun1,Yu Sun1,Christopher Marlein1,Charlotte Hellmich1,Kristian Bowles1,Stuart Rushworth1
1University of East Anglia

Pimozide: An antipsychotic drug suppresses brain tumor growth by targeting STAT3 signaling.

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Itishree Kaushik1,Alok Ranjan2,Blake Schwettmann3,Sanjay Srivastava4
1Texas tech university health sciences center,2NIH Clinical Center (CC),3not known,4Texas Tech University Health Sciences Center

Selective vulnerability of colorectal cancer (CRC) organoids to hypoxia-mimetic drug

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Chiara Asselborn1,Kevin Myant1,Alex von Kriegsheim1
1University of Edinburgh

Wnt/beta-catenin synergises with FOXG1 to drive exit from quiescence in neural stem cells, including glioblastoma stem cells

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Faye Robertson1,Harry Bulstrode1,Maria-Angeles Marques Torrejon1,Eoghan O'Duibhir1,Steve Pollard1
1University of Edinburgh

Tackling the Tgf-beta paradox via engineered organoids

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Michela Raponi1,Rene Jackstadt2,Stuart Aitken1,Philip Dunne3,Owen Sansom2,Kevin Myant1
1University of Edinburgh,2University of Glasgow,3Queens's University Belfast