212 abstracts found.



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Thyroid toxicities of Immune checkpoint inhibitors, Experience from Emirate of Dubai, UAE

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Mohamed Omara, Muhammad Latif, Elamin Abdelgader, Fatheya Alawadi, Faraz Khan, Maroun Elkhoury, Dalia Elshourbagy, Dina Hamza, S Hammad Tirmazy

Focal therapy compared to radical prostatectomy for non-metastatic prostate cancer: a propensity score matched study

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Deepika Reddy, Taimur Shah, Max Peters, Raj Persad, Manit Arya, Enrique Gomez-Gomes, Saiful Miah, David Eldred-Evans, Stephanie Guillaumier, Peter S.N. van Rossum, Marieke van Son, Feargus Hosking-Jervis, Tim Dudderidge, Richard Hindley, Emr Amara, Stuart McCracken, Damian Greene, Raj Nigam, Neil McCartan, Massimo Valerio, Suks Minhas, Naveed Afzal, Caroline Moore, Mark Emberton, Mathias Winkler, Hashim Ahmed

The importance of being given the name of a Clinical Nurse Specialist for experiences of cancer care: Population-based study using linked CPES-NCRAS Dataset

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Saleh Alessy1, Margreet Lüchtenborg, Janette Rawlinson, Matthew Baker, Elizabeth Davies
1King's College London

The acceptability and feasibility of a physical activity and metformin supplementation intervention in men with prostate cancer

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Megan Denne, Luke Robles, Lucy Hackshaw-McGeagh, Sally Adams, Richard Martin, Athene Lane

Breast Cancer Management Pathways during the COVID-19 pandemic. Outcomes from the UK ‘alert level 4’ phase of the B-MaP-C study.

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Baek Kim, Rajiv Dave1, Alona Courtney, Rachel O'Connell, Tim Rattay, Vicky P Taxiarchi, Jamie J Kirkham, Elizabeth Camacho, Patricia Fairbrother, Nisha Sharma, Christopher WJ Cartlidge, Kieran Horgan, Stuart A McIntosh, Daniel R Leff, Raghavan Vidya, Shelley Potter, Chris Holcombe, Ellen Copson, Charlotte E Coles, Ramsey I Cutress, Ashu Gandhi, Cliona Kirwan
1Manchester University NHS Foundation Trust

Deep Learning Auto-segmentation of Prostate Cancer from MRI data

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David Gillespie, Ian S. Boon, Connah Kendrick, Cheng S. Boon1, Moi Hoon Yap
1Clatterbridge Cancer Centre

Radiation and DMXAA limit tumour development in a urethane-induced lung cancer model through inflammatory response

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Kay Shigemori, Yanyan Jiang, Stephen Stribbling, Jennifer C. Martin, Luiza H.M. Lourenco, Anderson J. Ryan

Linking molecular signatures and gene regulatory programmes in Lung Carcinoids

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Clara Domingo-Sabugo1, Amit Mandal, Sarah Dwyer, Matthew Edwards, Deborah Morris-Rosendahl, Eric Lim, Andrew G. Nicholson, Mark Lathrop, William Cookson, Miriam Moffatt
1Imperial College London

Developing adaptive therapy to suppress the evolution of treatment resistance in high-gradeserous ovarian cancer

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Helen Hockings, Huang W, Lakatos E, Graham T, Lockley M

A novel ATM-Chk2-INCENP pathway delays abscission to prevent chromosome breakage in cytokinesis with chromatin bridges

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George Zachos, Eleni Petsalaki

The impact of the COVID-19 pandemic on thyroid cancer patients​

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Nikita Chander, Kate Farnell, Neil Tolley

Breast Cancer Hormone Receptor Status by Germline Cancer Predisposition Genes

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Grace Wei, Xia Wang

Optimal patient selection for personalized treatment in Georgian Gastric Cancer population

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Archil Aladashvili1, Roland Croner, Ia Pantsulaia, Natia Tchkadua, Irine Eliava, Nino Chigvinadze
1Tbilisi State medical University

Feasibility of manufacturing-scale bioproduction of novel next-generation 3D organoidcancer models in support of the Human Cancer Models Initiative

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Nirmal Perera, James Clinton, Penney McWilliams-Koeppen, Siddhartha Paul, Allison Ruchinskas, Dexhong Yin, Robert Newman

How do we manage brain metastases in the real world setting for patients with metastatic melanoma receiving immune checkpoint inhibition? Our experience within the North East of England.

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Abigail Gault, Nicola Cresti, Ruth Plummer

A multicentre analysis of safety of focal therapy for non-metastatic prostate cancer during the COVID-19 pandemic

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Deepika Reddy, Gaelle Fiard, Mariana Bertoncelli Tanaka, Juliet McQueen, Mohamed Noureldin, Tim - University Hospital Southampton Dudderidge, Richard Hindley, Amr Emara, Clement Orczyk, Caroline Moore, Manit Arya, Mark Emberton, Hashim Ahmed

Beyond skin deep: assessing outcomes of a ScarWork clinic treating people living with and beyond cancer from a range of tumour sites

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Beverley de Valois, Teresa Young, Clare Scarlett, Katrina Mindel

Results of a randomised phase III trial of dysphagia-optimised intensity modulated radiotherapy (Do-IMRT) versus standard IMRT (S-IMRT) in head and neck cancer.

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Chris Nutting, Keith Rooney, Bernadette Foran, Laura Pettit, Matthew Beasley, Laura Finneran, Justin Roe, Justine Tyler, Tom Roques, Audrey Cook, Imran Petkar, Shree Bhide, Devraj Srinivasan, Cheng Boon, Emma de Winton, Robert Frogley, Mark Sydenham, Marie Emson, Clare Griffin, Emma Hall, On behalf of DARS TMG

The Impact of COVID-19 on Wellbeing and Work Ability in the NHS Oncology Workforce: Initial results of the COVID-NOW Study

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Susana Banerjee1, Jonathan Lim, Eleanor Thorne, Konstantinos Kamposioras, Anna-Marie Stevens, Clare Shaw, Emma Foreman, Rachel Broadbent, Jennifer Cotton, Joanne Droney, Michael Flynn, James Stewart, Kylie Fitch, Laura Pope, Sara Lister, Claire Hardy
1The Royal Marsden NHS Foundation Trust

Deep learning-based segmentation and quantification of temporalis muscle for sarcopenia assessment is an independent prognostic factor in glioblastoma

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Ella Mi, Radvile Mauricaite, Lillie Pakzad-Shahabi, Katherine Pike, Matthew Williams

CD4 and CD8 T-cells contribute to the efficacy of the T-cell redirecting antibody CEA-TCB and TGFβ dampens its activity in in vitro colorectal cancer models

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Maria Semiannikova, Alice Newey, Fredrik Wallberg, Marina Bacac, Alan Melcher, Naureen Starling, David Cunningham, Ben Challoner, Andrew Woolston, Louise Barber, Marco Gerlinger

A qualitative study exploring weight management support for people living with and beyond cancer in Scotland. The patient perspective.

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Karen Barnett, Meena Bhagat, Robert Steele, Annie Anderson

Feasibility and acceptability of a community pharmacy referral service for suspected lung cancer symptoms

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Daniella Holland-Hart, Grace McCutchan, Harriet Quinn-Scoggings, Lucy Hill, Rachel Gemine, Savita Shanbag, Michael Abel, Kelly White, Angela Evans, Sarah Rees, Sarah Bowen, Gareth Collier, Kate Brain

Src kinase promotes actin patch formation to prevent chromosome breakage in cytokinesis with chromatin bridges

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Eleni Petsalaki, Sofia Balafouti, George Zachos

Effect of clinical parameters and demographics on outcomes in haemato-oncology patients with SARS-COV-2 infection: an inpatient analysis

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Shafaq Lashari, Sobia Sharif, Varun Mehra

Evaluation of a multi-stage AI analysis system to support prostate cancer diagnostic imaging

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Antony Rix, Jakub Suchanek, Aman Mehan, Chris Doran, Anwar Padhani, Christof Kastner, Tristan Barrett, Evis Sala

Does geodemographic segmentation explain differences in route of cancer diagnosis above and beyond person-level sociodemographic variables?

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Chloe Bright, Carolynn Gildea, Jennifer Lai, Lucy Elliss-Brookes, Georgios Lyratzopoulos

Standardising evaluation and reporting of outcomes of innovative invasive procedures and devices: the COHESIVE core outcome set

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Kerry Avery, Christin Hoffmann, Rhiannon Macefield, Nicholas Wilson, Angus McNair, Shelley Potter

Macrophages Mediate Response to PARP Inhibitor Treatment in Homologous Recombination-Proficient High-Grade Serous Ovarian Cancer

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Josip Vrancic, Susan Mason, Suzanne Dowson, Anna Kilbey, Sergio Lilla, Sara Zanivan, Iain McNeish, Karen Blyth, Seth Coffelt, Patricia Roxburgh

Estimating the risk of death from COVID Infection in Adult Cancer Patients

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Matthew Williams, Ella Mi, Kerlann Le Calvez, Jiarong Chen, Lillie Pakzad-Shahabi, Seema Dadhania, James Wang, Andrew Ho, Simon Rabinowicz

Unplanned hospital admissions toward the end of life for patients who received palliative chemotherapy for breast cancer

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Chloe Bright, Casey Dunlop, Rebecca Smittenaar, Cong Chen, Sean McPhail, David Dodwell, Mick Peake, Kathy Prichard-Jones, Emma Kipps

Living beyond cancer – survival outcomes after palliative radiotherapy

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Shelly English, Mohammed Abdul-Latif, Atia Khan, Anna Thompson

Embedding trials into clinical practice – Learning from the Covid -19 crisis

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Helen Winter1, Natalie Blencowe, Stephen Lang, Jeremy Bewley, Ben Gibbison, Jane Blazeby
1University of Bristol

Optimised radiation dose decisions using AI deep learning & reinforcement learning in small cell lung cancer.

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Deva Reddy1
1Care Oncology Clinic

Deconvolution of global gene expression profiles identifies differentially expressed immune-related gene profiles on aromatase inhibitor-resistant estrogen receptor positive tumours

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Milana Bergamino Sirvén1, Gabriele Morani, Joel Parker, Gene Schuster, Elena López-Knowles, Judith Bliss, Mitch Dowsett, Maggie Cheang
1Institute of Cancer Research (ICR)

Body mass index does not impact survival in colorectal cancer: An individual participant data meta-analysis of 9333 patients from seven randomized controlled trials (OCTOPUS Consortium)

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Lana Lai, Corinna Slawinski, Lee Malcomson, Richard Wilson, Richard Riley, Matthew Sperrin, Andrew G Renehan

The role of the RNA binding protein LARP-1 in the post-transcriptional regulation of cisplatin resistant ovarian cancer

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Chara Stavraka

Chmp4c is a novel kinetochore component that is required for optimal kinetochore-microtubule attachment and spindle checkpoint signaling

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Eleni Petsalaki, Maria Dandoulaki, George Zachos

Accuracy of cancer specific cause of death assigned through machine learning compared to an independent cause of death committee in a Cluster randomised trial of PSA testing for prostate cancer (CAP).

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Emma Turner1, Chris McWilliams, Eleanor Walsh, Raul Santos-Rodriguez, Avon Huxor, Richard Martin
1University of Bristol

Can we screen for pancreatic cancer? Identifying a sub-population of patients at high risk of subsequent diagnosis using machine learning techniques applied to primary care data

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Ananya Malhotra, Bernard Rachet, Audrey Bonaventure, Stephen Pereira, Laura Woods

Circulating insulin-like growth factor-I (IGF-I) concentrations and risk of 30 cancers: prospective analyses in UK Biobank

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Anika Knuppel1, Georgina K. Fensom, Eleanor L. Watts, Marc J. Gunter, Neil Murphy, Keren Papier, Aurora Perez-Cornago, Julie A. Schmidt, Karl Smith Byrne, Ruth C. Travis, Timothy J. Key
1Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford

Development and evaluation of a novel online training platform for genomics education in cancer care; preparing cancer clinicians for “Generation Genome”

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Alice Coulson, Vishakha Tripathi, Emma Cox, Johann Malawana, Zeina Beydoun, Vanessa Reeve, Anju Kulkarni

Cancer Catabolism reflected by Prognostic Nutritional Index (PNI) is a better predictor of prognosis in early bladder cancers than Systemic Inflammation measured by Neutrophil Lymphocyte Ratio (NLR)

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Jessica Davies, Santhanam Sundar

Systemic anti cancer therapy during COVID-19 pandemic, Dubai hospital experience

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Muhammad Farooq Latif1, Syed Hammad Hassan Tirmazy, Dalia Mahmoud El Shourbagy, Abdul Basit, Dina Hamza, Kaltar Das, Mohamed Hussien, Susheel Kumar, S Sajan, S Anto
1North wales cancer Treatment Centre

Shared Lives: Cancer – Developing an Online Resource to Support People Affected by Cancer through Making Academic Research Publicly Accessible.

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Heidi Green, David Nelson, Ros Kane, Kathie McPeake, Ruth Willis

Development of a model to predict hospital admission and severe outcome in cancer patients with COVID-19

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Rohan Shotton, Cong Zhou, Rebecca Lee, Ann Tivey, Talvinder Bhogal, Oskar Wysoki, Elena Dickens, Prerana Huddar, Hayley McKenzie, Hayley Boyce, Alec Maynard, Michael Rowe, Sam Khan, Leonie Eastlake, Angelos Angelakas, Mark Baxter, Ellen Copson, Laura Horsley, Anne Thomas, Caroline Wilson, Tim Cooksley, Andre Freitas, Carlo Palmieri, Caroline Dive, Anne Armstrong

Prostate  cancer detection using Artificial Intelligence in MRI

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Reddy Reddy, Dr.sanjai Addla, Dr.raghu Nath

Eosinophils are critical for response to immune checkpoint blockade in breast cancer and other cancer types

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Hannah Garner, Olga Blomberg, Lorenzo Spagnuolo, Leonie Voorwerk, Ewald van Dyk, Myriam Chalabi, Olga Isaeva, Noor Bakker, Kelly Kersten, Chris Klaver, Maxime Duijst, Dorien Pastoors, Cheei-Sing Hau, Kim Vrijland, Elisabeth Raeven, Louisa Hoes, Willemijn Theelen, Paul Baas, Emile Voest, Lodewyk Wessels, Karin de Visser, Marleen Kok

The provision of nutritional advice and care for cancer patients: a UK national survey of health care professionals

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Jane Murphy, Fehmidah Munir, Fiona Davey, Laura Miller, Ramsey Cutress, Rhys White, Megan Lloyd, Justin Roe, Carol Granger, Sorrel Burden, Lesley Turner

Deciphering epigenetic encoding, heritability and plasticity of glioma transcriptional cell states via single-cell multi-omics

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Federico Gaiti, Ronan Chaligne, Dana Silverbush, Joshua Schiffman, Hannah Weisman, Lloyd Kluegel, Simon Gritsch, Sunil Deochand, Alyssa Richman, Johanna Klughammer, Tommaso Biancalani, Christoph Muus, Caroline Sheridan, Alicia Alonso, Franco Izzo, Orit Rozenblatt-Rosen, Aviv Regev, Mario Suvà, Dan Landau