254 abstracts found.



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Outcomes of patients with confirmed cancer of unknown primary: a 10-year analysis

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Aoife Gatenby1, Mark Stares1, Karin Purshouse2, Gillian Knowles1, Rachel Haigh1, Jenny Irvine1, Rebekah Patton1, Jo McGinty1, Alan Christie1, Marjory MacLennan1, Colin Barrie1, Sally Clive1
1Edinburgh Cancer Centre, 2University of Edinburgh

Associations between markers of social functioning and depression and quality-of-life among head and neck cancer survivors: findings from the HN5000 study

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Linda Sharp1, Liya Lu1, Laura-Jane Watson2, Sam Harding3, Joanne Patterson4
1Newcastle University, 2South Tyneside and Sunderland NHS Foundation Trust, 3North Bristol NHS Trust, 4University of Liverpool

Trial recruitment challenges – lessons from the ROCS study of radiotherapy after stent insertion in incurable oesophageal cancer

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Anthony Byrne1, Douglas Adamson2, Noreen Hopewell-Kelly3, Lisette Nixon4, Debbie Forbes2, Mim Evans5, Catharine Porter4, Jane Blazeby6, Gareth Griffiths7, Annmarie Nelson1, Martina Svobodova4, Jim Fitzgibbon1, Stephen Thomas8, Anthony Millin9, Tom Crosby9, John Staffurth1, Christopher Hurt4
1Cardiff University, 2NHS Tayside, 3University of the West of England (UWE), 4Cardiff University – Centre for Trials Research, 5Cardiff and Vale University Health Board (CVUHB), 6University of Bristol, 7University of Southampton, 8Patient, 9Velindre Cancer Centre

Knowledge, Perceptions and Practice of physical activity in high-grade glioma patients in Bangladesh: a mixed-method study protocol

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Ishrat Islam1, Silvia Goss1, Annmarie Nelson1, Anthony Byrne2
1Cardiff University, 2NHS

Tepotinib in patients with MET exon 14 (METex14) skipping NSCLC (VISION trial results) — METex14 should be added to UK testing directory

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Shobhit Baijal1, Wanda Cui2, Xiuning Le3, Enriqueta Felip4, Hiroshi Sakai5, Marina Chiara Garassino6, Remi Veillon5, Egbert Smit7, Audrey Seronde5, Christoph Menzel5, Rolf Bruns5, Gordon Otto5, Paul Paik8
1Heart of England NHS Foundation Trust, 2Royal Marsden NHS Foundation Trust, 3MD Anderson Cancer Center, 4Vall d’Hebron Institute of Oncology, 5Other, 6Fondazione IRCCS Istituto Nazionale dei Tumori, 7Netherlands Cancer Institute, 8Memorial Sloan-Kettering Cancer Center

Infection risk and return to work advice in patients with solid tumours: a mixed methods study

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Louise Hancock1, Damien McElvenny1
1Other

An Apple A Day keeps the Doctor Away? A Review of the Impact of the Neutropenic Diet on Patients with a Haematological Malignancy.

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Gemma Spencer1, Jean Duckworth1, Hazel Partington1
1University of Central Lancashire

Screening asymptomatic men for prostate cancer: a comparison of international guidelines on PSA testing

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May de La Rue1, Thomas Greenslade1, Sherena Jackson1, Anna John1, Shahida Wahid1, Naomi Williams1, Emma Turner1, Richard Martin1
1University of Bristol

Effect of the electron return effect on acute rectal toxicity in moderately-hypofractionated and stereotactic ablative radiotherapy (SABR) prostate cancer treatment schedules: A preliminary study

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Milad Tavakoli1, Eliana Vasquez-Osorio1, Marcel Van Herk1, Gareth Price1, Rob Chuter1, Abigael Clough1, Robin Portner1, Ananya Choudhury1, Jane Shortall1
1The Christie NHS Foundation Trust

PERSPECTIVE: Tepotinib + cetuximab for RAS/BRAF wild-type left-sided metastatic colorectal cancer (mCRC) and acquired resistance to anti-EGFR antibody therapy due to MET amplification (METamp)

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Stephen Falk1, David Cunningham2, Janet Graham3, Justin Mencel2, Paul Ross4, Barbara Ellers-Lenz1, Gordon Otto1, Audrey Seronde1, Josep Tabernero5
1Other, 2Royal Marsden NHS Foundation Trust, 3Beatson West of Scotland Cancer Centre, 4Guy’s and St Thomas’ NHS Foundation Trust, 5Vall d’Hebron Institute of Oncology

Exploring the role of RFWD3 in chemosensitivity of high grade serous ovarian cancer.

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Sarah Taylor1, Robb Hollis2, Charlie Gourley2, Simon Herrington2, Mark Arends2, Simon Langdon2
1Cancer Research UK (CRUK) Edinburgh Centre, 2Edinburgh Cancer Centre

Outcomes of Patients with Locally Advanced Pancreatic Cancer in a Large University Hospital

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Gemma Searle1, Arvind Tripathy2, Sharmila Sothi2, Hannah Tween2, Jawad Ahmad2, Gabriele Marangoni2, Saboor Khan2, For Tai Lam2, Martin Scott-Brown2
1Other, 2University Hospitals Coventry and Warwickshire NHS Trust

Strategies for improving access to clinical trials by teenagers and young adults with cancer: A qualitative study of health professionals’ views

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Angela Jesudason1, Dorothy Boyle2, David Cameron3, Fiona Cowie4, Larry Hayward2, Nicholas Heaney4, Julia Lawton3
1NHS Lothian, 2Edinburgh Cancer Centre, 3University of Edinburgh, 4Beatson West of Scotland Cancer Centre

Evaluation of MRI for detection and staging of relapse in stage I seminoma: Data from independent central scan review in the randomised TRial of Imaging and Surveillance in Seminoma Testis (TRISST)

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Aslam Sohaib1, Sarah Swift2, Laura Murphy3, Fay Cafferty3, Robert Huddart1, Gordon Rustin4, Dipa Noor3, Simona Wade3, Francesca Schiavone3, Elizabeth James3, Richard Kaplan3, Johnathan Joffe5
1Institute of Cancer Research (ICR), 2St James’s Hospital, 3Other, 4Mount Vernon Cancer Centre, 5Calderdale and Huddersfield NHS Foundation Trust

Efforts to achieve earlier diagnosis of renal tumours in childhood are required to improve survival rates in the UK and Ireland

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Reem Al-Saadi1, Oystein Olsen2, Tom Watson2, Susan Shelmerdine2, Gordan Vujanic3, Richard Williams4, Mark Weeks1, Jessica Bate5, Jesper Brok3, Sabine Irtan3, Kristina Dzhuma2, Minou Oostveen2, Vesna Pavasovic2, Angela Lopez2, Suzanne Tugnait6, Mark Powis7, Dan Saunders8, Sucheta Vaidya9, Lisa Howell10, Tanzina Chowdury2, Kathy Pritchard-Jones6
1UCL Great Ormond Street Institute of Child Health, 2Great Ormond Street Hospital for Children NHS Foundation Trust, 3Other, 4Imperial College London, 5University Hospital Southampton NHS Foundation Trust, 6University College London (UCL), 7Leeds Teaching Hospitals NHS Trust, 8The Christie NHS Foundation Trust, 9Royal Marsden NHS Foundation Trust, 10Alder Hey Children’s NHS Foundation Trust

Optimising systemic therapy for octogenarians with lung cancer

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George Kostopoulos1, Colin Lindsay2
1No affiliation, 2NHS

SELIMETRY: resensitising iodine refractory differentiated thyroid cancer to radioiodine

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Jon Wadsley1, Gemma Ainsworth2, Matthew Beasley3, Sarah Brown2, Amy Coulson2, Yong Du4, Kate Farnell5, Glenn Flux4, Kate Garcez6, Matthew Griffin7, Helen Howard2, Jennifer Marshall8, Laura Moss9, Kate Newbold4, Abigail Pascoe7, Jayne Swain2, Jan Taprogge4, Andrew Weaver10, Katie Wood11
1Sheffield Teaching Hospitals NHS Foundation Trust, 2University of Leeds, 3University Hospitals Bristol NHS Foundation Trust, 4Royal Marsden NHS Foundation Trust, 5Butterfly Thyroid Cancer Trust, 6The Christie NHS Foundation Trust, 7Nottingham University Hospitals NHS Trust, 8University Hospital Southampton NHS Foundation Trust, 9Velindre Cancer Centre, 10Oxford University Hospitals NHS Foundation Trust, 11Royal Surrey NHS Foundation Trust

Patients’ perspectives on a talking therapy for cancer aftercare

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Sheila Donovan1, Elisavet Moschopoulou1, Damien Ridge2, Trudie Chalder3, Imran Khan1, Stephanie Taylor1
1Queen Mary University of London, 2University of Westminster, 3King’s College London (KCL)

Palliative radiotherapy after oesophageal cancer stent insertion: a multicentre, phase 3, randomised controlled trial (ROCS)

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Douglas Adamson1, Anthony Byrne1, Catharine Porter1, Jane Blazeby1, Gareth Griffiths1, Annmarie Nelson1, Bernadette Sewell1, Mari Jones1, Martina Svobodova1, Deborah Fitzsimmons1, Lisette Nixon1, Jim Fitzgibbon2, Stephen Thomas2, Anthony Millin3, Tom Crosby3, John Staffurth3, Christopher Hurt1
1Other, 2No affiliation, 3Velindre Cancer Centre

Mesothelioma patient and carer experience research: a Research Prioritisation Exercise

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Bethany Taylor1, Clare Gardiner1, Stephanie Ejegi-Memeh1, Madeleine Harrison1, Michaela Senek1, Virginia Sherborne1, Angela Tod1
1University of Sheffield

Survival outcomes and treatment decisions in breast cancer patients following complete pathological response to neoadjuvant chemotherapy

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Natalie Martin1, Julia Pasztorova1, Isabella Hibell1, Duncan Wheatley2
1University of Exeter, 2Royal Cornwall Hospitals NHS Trust

REmote Follow-up – Lessons and Experiences during Covid-19 Time In ONcology Services (REFLECTIONS) -service evaluation

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Richard Simcock1, Val Jenkins2, Rachel Starkings2, Leroy Okonta3, Susan Catt2
1University Hospitals Sussex, 2Brighton and Sussex Medical School, 3Brighton and Sussex University Hospitals NHS Trust

Cancer incidence by broad ethnic group, England, 2013-2017

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Christine Delon1, Katrina Brown1, Nick Payne1, Yannis Kotrotsios1, Sally Vernon2, Jon Shelton1
1Cancer Research UK (CRUK), 2Public Health England

Modelling the episodes of care for iron deficiency anaemia patients in a secondary-care centre using continuous-time multi-state Markov chain

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Orouba Almilaji1, Jonathon Snook2, Sharon Docherty1
1Bournemouth University, 2Poole Hospital NHS Foundation Trust

How do people with advanced cancer, and their close persons, experience continuity in primary care? A mixed-methods systematic review

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Emilie Couchman1, Steph Ejegi-Memeh1, Sarah Mitchell1, Clare Gardiner1
1University of Sheffield

Research, Response and Recovery: Clatterbridge Cancer Centre and the COVID-19 pandemic

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Maria Maguire1, Emma Whitby1, Jane Tinsley1, Michelle Moffitt1, Fiona Keys1, Gillian Heap1, Nagesh Kalakonda1, Sheena Khanduri1
1Clatterbridge Cancer Centre NHS Foundation Trust

Incidence and Clinical Significance of NUDT15 enzyme polymorphisms in a London population of paediatric Acute Lymphoblastic Leukaemia (ALL) patients treated at Great Ormond Street Hospital, London.

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Lamia Samrin-Balch1, Sujith Samarasinghe1, Ajay Vora Vora1
1Great Ormond Street Hospital for Children NHS Foundation Trust

Rectal radiotherapy during the COVID-19 pandemic

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Stephen Robinson1, Fatima Mahmood2, Marib Khan2, Peter Dunn2, Rizvana Ahmad3, Dolan Basak2, Susan Cleator2, Shiva Gayadeen2, Kitrick Perry2, Pippa Riddle3
1Imperial College Healthcare Trust, 2Imperial College Healthcare NHS Trust, 3West Middlesex University Hospital

Investigating workforce barriers to radiotherapy clinical trials delivery

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Amy Taylor1, Pam Shuttleworth2
1Sheffield Teaching Hospitals NHS Foundation Trust, 2Leeds Teaching Hospitals NHS Trust

Can the gut microbiota both radiosensitise tumours and spare normal tissue toxicity?

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Chee Kin Then1, Salome Paillas1, Xuedan Wang2, Anne E Kiltie1
1Oxford Institute for Radiation Oncology, 2University of Oxford

The effect of clinical decision-making for starting systemic anti-cancer treatments in response to the coronavirus pandemic in England: A Retrospective Analysis

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James Clark1, Dominic Dwyer2, Nina Pinwill2, Peter Clark2, Peter Johnson2, Allan Hackshaw3
1Imperial College London, 2NHS England, 3University College London (UCL)

Estimating prognosis in patients with metastatic solid tumours; do oncologists and non-cancer clinicians agree and what implications are there?

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Caroline Michie1, Maithili Vijayakumar2, Rebecca Muirhead3, Heather Molyneux4, Jahangeer Malik4, Colin Barrie4, Sarah McKelvie5
1Edinburgh Cancer Centre, 2No affiliation, 3University of Oxford, 4NHS Lothian, 5Oxford University Hospitals NHS Foundation Trust

Is A Body Shape Index (ABSI) associated with incident cancer? – Findings from the UK Biobank prospective cohort study

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Solange Parra Soto1, Fiona C Malcomson2, Jill P Pell1, Frederick K Ho1, Linda Sharp2, John C Mathers2, Carlos Celis-Morales1
1University of Glasgow, 2Newcastle University

Cost-effectiveness of eRAPID eHealth intervention for online symptom management during chemotherapy

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Galina Velikova1, Bryony Dawkins1, Kate Absolom1, Lorraine Warrington1, Jenny Hewison1, Eleanor Hudson1, Andrea Gibson1, Marie Holmes1, Zoe Rogers1, Robert Carter1, Julia Brown1, Claire Hulme2
1University of Leeds, 2University of Exeter

Urine metabolites predict the last weeks and days of life in lung cancer patients

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Seamus Coyle1, James Baker2, Hannah Coleman3, Elinor Chapman3, Brendan Norman3, Andrew Davison4, Stephen Mason3, David Hughes3, Mark Boyd3, John Ellershaw3, Chris Probert3
1Clatterbridge Cancer Centre NHS Foundation Trust, 2No affiliation, 3University of Liverpool, 4Liverpool University Hospitals NHS Foundation Trust

Multimorbidity in patients living with and beyond cancer: protocol for a scoping review

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Tahania Ahmad1, Tahania Ahmad1, Dipesh Gopal1, Steph Taylor1, Dayem Ullah1
1Queen Mary University of London

Bladder empty radiotherapy for prostate cancer (BERP-A) – a single centre feasibility study.

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Kimberley Durno1, Mark Prentice1, Sarah Needleman1
1Royal Free London NHS Foundation Trust

Please write to me. An audit of content and readability in oncology correspondence

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Sahiti Siri Kalapu1, Richard Simcock2
1Brighton and Sussex Medical School, 2Brighton and Sussex University Hospitals NHS Trust

TBX2/TBX3-targeting non-oncological drugs limit glioblastoma cell viability

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Arish Mudra Rakshasa-Loots1, Saif Khan2, Victoria Damerell2, Sharon Prince2
1University of Edinburgh, 2University of Cape Town

Real-world effectiveness of CDK4/6 inhibitors for metastatic hormone receptor-positive and HER2-negative breast cancer

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Hiu Kwan Carolyn Tang1, Christina Peters1, Sasagu Kuozumi2, Sarah Khan1
1Nottingham City Hospital, 2Other

Adjusting for co-morbidity in observational cancer studies; a systematic review to assess alignment between index and study

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Antonio Borrelli1, Katie Spencer2, Rebecca Birch3
1University of Leeds, 2Leeds Teaching Hospitals NHS Trust, 3Leeds Institute of Data Analytics (LIDA)

The HER2-RADiCAL study (Response ADaptive CAre pLan) – Tailoring treatment for HER2 positive early breast cancer

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Iain Macpherson1, Stuart McIntosh2, Lucy Kilburn3, Holly Tovey3, Sarah Kernaghan3, Katie Goddard3, Indrani Bhattacharya4, Clinton Boyd5, Charlotte Coles6, Cliona Kirwan7, Mairead Mackenzie8, Ciara O’Brien7, Alistair Ring9, Claire Snowdon3, Hilary Stobart8, Duncan Wheatley10, Andrew Wardley11, Abeer Shaaban12, Peter Hall13, David Cameron13, Judith Bliss3
1University of Glasgow, 2Queen’s University Belfast, 3Institute of Cancer Research (ICR), 4Cambridge University Hospitals NHS Foundation Trust, 5Belfast Health and Social Care Trust, 6University of Cambridge, 7The Christie NHS Foundation Trust, 8Independent Cancer Patients’ Voice (ICPV), 9Royal Marsden NHS Foundation Trust, 10Royal Cornwall Hospitals NHS Trust, 11Other, 12University Hospitals Birmingham NHS Foundation Trust, 13University of Edinburgh

Female immunity protects from cutaneous squamous cell carcinoma

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Timothy Budden1, Caroline Gaudy-Marqueste2, Sarah Craig1, Yuan Hu2, Charles Earnshaw1, Shilpa Gurung1, Amelle Ra2, Victoria Akhras2, Patrick Shenjere3, Ruth Green4, Lynne Jamieson4, John Lear4, Luisa Motta4, Carlos Caulin2, Deemish Oudit3, Simon Furney5, Amaya Viros1
1Cancer Research UK (CRUK) Manchester Institute, 2Other, 3The Christie NHS Foundation Trust, 4Salford Royal NHS Foundation Trust, 5Royal College of Surgeons in Ireland

Outcomes of treatment modalities for melanoma metastatic to the gastrointestinal tract

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Azreen Afzal1, Grace Williams1, Maria Marples2
1University of Leeds, 2Leeds Teaching Hospitals NHS Trust

Outcomes of patients who progressed while receiving avelumab + axitinib (A + Ax) and received subsequent treatment (Tx) in JAVELIN Renal 101

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Laurence Albiges1, Paul Nathan2, Martin Voss3, Brian Rini4, Gwenaëlle Gravis1, Marc-Oliver Grimm1, Georg Bjarnason1, Yoshihiko Tomita1, Konstantin Penkov1, Bradley McGregor5, Bo Huang6, Despina Thomaidou6, Mariangela Mariani1, Alessandra di Pietro1, Toni Choueiri5
1Other, 2Mount Vernon Cancer Centre, 3Memorial Sloan-Kettering Cancer Center, 4Vanderbilt-Ingram Cancer Center, 5Dana-Farber Cancer Institute, 6Pfizer

Genome-wide association study to identify genetic markers predictive of early-onset capecitabine-induced toxicity

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Ik Shin Chin1, David Church2, Rachel Kerr2, David Kerr2, Claire Palles1
1University of Birmingham, 2University of Oxford

Risk of bowel obstruction in patients undergoing neoadjuvant chemotherapy for high-risk colon cancer: A nested case-control matched analysis of an international randomised controlled trial (FOxTROT)

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James Glasbey1, Prof. Dion G Morton1, . FOxTROT Collaborating Group1
1University of Birmingham

A predictive tool for assessing bone lesions in malignancy of undefined primary origin

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Sean O’Reilly1, Dylan Guo Liang Yong2, Rachel Haigh3, Gillian Knowles3, Jackie Brown3, Colin Barrie3, Sally Clive3, Mark Stares1
1University of Edinburgh, 2NHS Lothian, 3Edinburgh Cancer Centre

Identifying molecular mediators of the relationship between body mass index and endometrial cancer risk: a Mendelian randomization analysis

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Emma Hazelwood1, Richard Martin1, James Yarmolinsky1
1University of Bristol

Adiposity, exercise, diet, and outcomes after breast cancer diagnosis: World Cancer Research Fund (WCRF)/American Institute for Cancer Research (AICR) systematic literature review and meta-analysis.

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Margarita Cariolou1, Katia Balducci1, Nerea Becerra-Tomás1, Leila Abar1, Dagfinn Aune1, Georgios Markozannes1, Neesha Nanu1, Ana Rita Vieira1, Edward L Giovannucci2, Marc J Gunter3, Alan Jackson4, Ellen Kampman2, Viv Lund2, Kate Allen5, Nigel Brockton6, Helen Crocker5, Daphne Katsikioti5, Deirdre McGinley-Gieser6, Panagiota Mitrou5, Martin Wiseman5, Anne McTiernan7, Steven Clinton2, Teresa Norat1, Konstantinos K Tsilidis1, Doris S.M Chan1
1Imperial College London, 2Other, 3International Agency for Research on Cancer (IARC), 4University of Southampton, 5World Cancer Research Fund International, 6American Institute for Cancer Research, 7Fred Hutchinson Cancer Research Center